Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
Toce_1679D-proline reductase (dithiol); KEGG: cbf:CLI_3802 glycine/sarcosine/betaine reductase, component B, subunits alpha and beta; PRIAM: D-proline reductase (dithiol); SPTR: Glycine/sarcosine/betaine reductase, component B, subunits alpha and beta; PFAM: Glycine/sarcosine/betaine reductase component B subunits. (292 aa)    
Predicted Functional Partners:
Toce_1681
KEGG: aoe:Clos_0030 D-proline reductase (dithiol); PRIAM: D-proline reductase (dithiol); SPTR: D-proline reductase (Dithiol); PFAM: Glycine/sarcosine/betaine reductase selenoprotein B (GRDB); TIGRFAM: selenoprotein B, glycine/betaine/sarcosine/D-proline reductase family.
  
 0.996
Toce_1678
D-proline reductase (dithiol); InterPro IPR015417; KEGG: cbl:CLK_1856 PrdE protein; PFAM: Glycine/sarcosine/betaine reductase complex protein B alpha and beta subunits; PRIAM: D-proline reductase (dithiol); SPTR: D-proline reductase (Dithiol); PFAM: Glycine/sarcosine/betaine reductase component B subunits.
   
 0.995
Toce_1677
COGs: COG3938 Proline racemase; InterPro IPR008794:IPR020053; KEGG: amt:Amet_0671 proline racemase; PFAM: proline racemase; PRIAM: Proline racemase; SPTR: Proline racemase; PFAM: Proline racemase; Belongs to the proline racemase family.
 
  
 0.991
Toce_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.965
Toce_1683
D-proline reductase (dithiol); InterPro IPR015417; KEGG: cbl:CLK_3050 glycine/sarcosine/betaine reductase, component B, subunits alpha and beta; PFAM: Glycine/sarcosine/betaine reductase complex protein B alpha and beta subunits; PRIAM: D-proline reductase (dithiol); SPTR: Glycine/sarcosine/betaine reductase, component B, subunits alpha and beta; PFAM: Glycine/sarcosine/betaine reductase component B subunits.
 
  
0.961
Toce_1680
KEGG: cbf:CLI_2520 putative D-proline reductase, PrdB subunit, selenocysteine-containing; SPTR: Putative D-proline reductase, PrdB subunit, selenocysteine-containing.
 
     0.914
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 0.910
Toce_1489
Dihydrodipicolinate reductase; COGs: COG3804 conserved hypothetical protein related to dihydrodipicolinate reductase; InterPro IPR000846; KEGG: tte:TTE1234 hypothetical protein; PFAM: dihydrodipicolinate reductase; SPTR: Putative uncharacterized protein; PFAM: Dihydrodipicolinate reductase, N-terminus.
     
 0.906
Toce_1684
Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; COGs: COG4656 NADH:ubiquinone oxidoreductase subunit RnfC; InterPro IPR011538:IPR019554; KEGG: cbl:CLK_3051 respiratory-chain NADH dehydrogenase family protein; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Soluble ligand binding domain; SPTR: Respiratory-chain NADH dehydrogenase family protein; PFAM: Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain; TIGRFAM: electron transport complex, RnfABCDGE type, C subunit.
 
   
 0.890
Toce_1214
Metallophosphoesterase; COGs: COG0420 DNA repair exonuclease; InterPro IPR004843; KEGG: cth:Cthe_0945 metallophosphoesterase; PFAM: metallophosphoesterase; SPTR: Metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase.
   
 0.882
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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