Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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Toce_1688COGs: COG0793 Periplasmic protease; InterPro IPR004447:IPR001478:IPR005151; KEGG: tit:Thit_1774 carboxyl-terminal protease; PFAM: peptidase S41; PDZ/DHR/GLGF domain protein; PRIAM: C-terminal processing peptidase; SMART: peptidase S41; PDZ/DHR/GLGF domain protein; SPTR: Carboxyl-terminal protease; TIGRFAM: carboxyl-terminal protease; PFAM: Peptidase family S41; PDZ domain (Also known as DHR or GLGF); TIGRFAM: C-terminal peptidase (prc); Belongs to the peptidase S41A family. (415 aa)    
Predicted Functional Partners:
Toce_1588
COGs: COG0438 Glycosyltransferase; InterProIPR001296:IPR013216:IPR001173:IPR019734:IPR 013026:IPR000276; KEGG: tnp:Tnap_0554 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; Methyltransferase type 11; glycosyl transferase group 1; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase family 2; PFAM: Methyltransferase domain; Glycosyl transferases group 1; Glycosyl transferase family 2.
  
 
 0.869
Toce_1687
PDZ/DHR/GLGF domain protein; InterPro IPR001478; KEGG: tpd:Teth39_0567 PDZ/DHR/GLGF domain-containing protein; PFAM: PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: PDZ/DHR/GLGF domain protein; PFAM: PDZ domain (Also known as DHR or GLGF).
  
  
 0.856
Toce_1690
Protein of unknown function DUF214; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
     0.656
Toce_1689
Peptidase M23; COGs: COG4942 Membrane-bound metallopeptidase; InterPro IPR016047; KEGG: tte:TTE1975 membrane proteins related to metalloendopeptidase; PFAM: Peptidase M23; SPTR: Membrane proteins related to metalloendopeptidases; PFAM: Peptidase family M23.
   
 
 0.638
ftsE
Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
       0.582
Toce_1250
Membrane-associated zinc metalloprotease; COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR004387:IPR008915:IPR001478; KEGG: tte:TTE1401 membrane-associated Zn-dependent protease 1; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Predicted membrane-associated Zn-dependent protease 1; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP.
 
  
 0.515
Toce_0487
O-antigen polymerase; InterPro IPR019734:IPR013026:IPR007016; KEGG: tte:TTE0644 TPR repeat-containing protein; PFAM: O-antigen polymerase; SPTR: TPR-repeat-containing proteins; PFAM: O-Antigen ligase.
  
 
 0.451
secA
Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family.
 
  
 0.442
Toce_0197
S-layer domain protein; InterPro IPR001119; KEGG: tit:Thit_0105 S-layer domain protein; PFAM: S-layer domain protein; SPTR: S-layer domain protein; PFAM: S-layer homology domain.
    
 
 0.418
Toce_0616
NLP/P60 protein; COGs: COG0791 Cell wall-associated hydrolase (invasion-associated protein); InterPro IPR000064; KEGG: tle:Tlet_0253 NLP/P60 protein; PFAM: NLP/P60 protein; SPTR: NLP/P60 protein; PFAM: NlpC/P60 family; Bacterial SH3 domain.
    
 
 0.418
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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