Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ftsECell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. (228 aa)    
Predicted Functional Partners:
Toce_1690
Protein of unknown function DUF214; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
 0.999
Toce_2172
Protein of unknown function DUF214; COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: tit:Thit_0219 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: Putative uncharacterized protein; PFAM: Predicted permease.
   
 0.921
Toce_2163
Protein of unknown function DUF214; COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: aoe:Clos_2614 hypothetical protein; PFAM: protein of unknown function DUF214; SPTR: Putative uncharacterized protein; PFAM: Predicted permease.
   
 0.919
Toce_1571
Amino acid ABC transporter membrane protein, PAAT family; COGs: COG0765 ABC-type amino acid transport system permease component; InterPro IPR010065:IPR000515; KEGG: tex:Teth514_0469 polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Polar amino acid ABC transporter, inner membrane subunit; TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: amine acid ABC transporter, permease protein, 3-TM region, Hi [...]
    
 0.899
Toce_1689
Peptidase M23; COGs: COG4942 Membrane-bound metallopeptidase; InterPro IPR016047; KEGG: tte:TTE1975 membrane proteins related to metalloendopeptidase; PFAM: Peptidase M23; SPTR: Membrane proteins related to metalloendopeptidases; PFAM: Peptidase family M23.
 
   
 0.880
Toce_1687
PDZ/DHR/GLGF domain protein; InterPro IPR001478; KEGG: tpd:Teth39_0567 PDZ/DHR/GLGF domain-containing protein; PFAM: PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: PDZ/DHR/GLGF domain protein; PFAM: PDZ domain (Also known as DHR or GLGF).
  
  
 0.719
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
  
 0.603
scpA
Chromosome segregation and condensation protein ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
  
  
 0.595
Toce_1688
COGs: COG0793 Periplasmic protease; InterPro IPR004447:IPR001478:IPR005151; KEGG: tit:Thit_1774 carboxyl-terminal protease; PFAM: peptidase S41; PDZ/DHR/GLGF domain protein; PRIAM: C-terminal processing peptidase; SMART: peptidase S41; PDZ/DHR/GLGF domain protein; SPTR: Carboxyl-terminal protease; TIGRFAM: carboxyl-terminal protease; PFAM: Peptidase family S41; PDZ domain (Also known as DHR or GLGF); TIGRFAM: C-terminal peptidase (prc); Belongs to the peptidase S41A family.
       0.582
ecfT
Cobalt transport protein; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
    
 0.569
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (12%) [HD]