| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Toce_0607 | Toce_1588 | Toce_0607 | Toce_1588 | Arsenite methyltransferase; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: sus:Acid_4410 arsenite S-adenosylmethyltransferase; PFAM: Methyltransferase type 11; PRIAM: Arsenite methyltransferase; SPTR: Methyltransferase type 11; PFAM: Methyltransferase domain. | COGs: COG0438 Glycosyltransferase; InterProIPR001296:IPR013216:IPR001173:IPR019734:IPR 013026:IPR000276; KEGG: tnp:Tnap_0554 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; Methyltransferase type 11; glycosyl transferase group 1; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase family 2; PFAM: Methyltransferase domain; Glycosyl transferases group 1; Glycosyl transferase family 2. | 0.687 |
| Toce_0607 | Toce_1730 | Toce_0607 | Toce_1730 | Arsenite methyltransferase; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: sus:Acid_4410 arsenite S-adenosylmethyltransferase; PFAM: Methyltransferase type 11; PRIAM: Arsenite methyltransferase; SPTR: Methyltransferase type 11; PFAM: Methyltransferase domain. | Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: hmo:HM1_1960 heptaprenyl diphosphate synthase component II, putative; PFAM: Polyprenyl synthetase; SPTR: Heptaprenyl diphosphate synthase component ii, putative; PFAM: Polyprenyl synthetase; TIGRFAM: heptaprenyl diphosphate synthase component II; Belongs to the FPP/GGPP synthase family. | 0.532 |
| Toce_1253 | Toce_1730 | Toce_1253 | Toce_1730 | Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: hmo:HM1_1960 heptaprenyl diphosphate synthase component II, putative; PFAM: Polyprenyl synthetase; SPTR: Heptaprenyl diphosphate synthase component ii, putative; PFAM: Polyprenyl synthetase; TIGRFAM: heptaprenyl diphosphate synthase component II; Belongs to the FPP/GGPP synthase family. | 0.575 |
| Toce_1253 | ispH | Toce_1253 | Toce_1156 | Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.680 |
| Toce_1551 | Toce_1728 | Toce_1551 | Toce_1728 | UbiA prenyltransferase; COGs: COG1575 1 4-dihydroxy-2-naphthoate octaprenyltransferase; InterPro IPR000537; KEGG: cth:Cthe_3041 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: UbiA prenyltransferase; PFAM: UbiA prenyltransferase family. | UbiA prenyltransferase; COGs: COG1575 1 4-dihydroxy-2-naphthoate octaprenyltransferase; InterPro IPR000537:IPR005479; KEGG: tte:TTE2481 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: 1,4-dihydroxy-2-naphthoate octaprenyltransferase. | 0.925 |
| Toce_1551 | Toce_1729 | Toce_1551 | Toce_1729 | UbiA prenyltransferase; COGs: COG1575 1 4-dihydroxy-2-naphthoate octaprenyltransferase; InterPro IPR000537; KEGG: cth:Cthe_3041 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: UbiA prenyltransferase; PFAM: UbiA prenyltransferase family. | FMN-binding domain protein; COGs: COG4939 Major membrane immunogen membrane-anchored lipoprotein; InterPro IPR007329; KEGG: lsg:lse_2542 lipoprotein, putative; PFAM: FMN-binding domain protein; SPTR: Lmo2637 protein; PFAM: FMN-binding domain. | 0.719 |
| Toce_1551 | Toce_1730 | Toce_1551 | Toce_1730 | UbiA prenyltransferase; COGs: COG1575 1 4-dihydroxy-2-naphthoate octaprenyltransferase; InterPro IPR000537; KEGG: cth:Cthe_3041 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: UbiA prenyltransferase; PFAM: UbiA prenyltransferase family. | Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: hmo:HM1_1960 heptaprenyl diphosphate synthase component II, putative; PFAM: Polyprenyl synthetase; SPTR: Heptaprenyl diphosphate synthase component ii, putative; PFAM: Polyprenyl synthetase; TIGRFAM: heptaprenyl diphosphate synthase component II; Belongs to the FPP/GGPP synthase family. | 0.723 |
| Toce_1551 | Toce_1731 | Toce_1551 | Toce_1731 | UbiA prenyltransferase; COGs: COG1575 1 4-dihydroxy-2-naphthoate octaprenyltransferase; InterPro IPR000537; KEGG: cth:Cthe_3041 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: UbiA prenyltransferase; PFAM: UbiA prenyltransferase family. | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG1252 NADH dehydrogenase FAD-containing subunit; InterPro IPR013027:IPR011637; KEGG: hor:Hore_14860 NADH dehydrogenase, FAD-containing subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; DoxX family protein; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; DoxX. | 0.863 |
| Toce_1588 | Toce_0607 | Toce_1588 | Toce_0607 | COGs: COG0438 Glycosyltransferase; InterProIPR001296:IPR013216:IPR001173:IPR019734:IPR 013026:IPR000276; KEGG: tnp:Tnap_0554 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; Methyltransferase type 11; glycosyl transferase group 1; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase family 2; PFAM: Methyltransferase domain; Glycosyl transferases group 1; Glycosyl transferase family 2. | Arsenite methyltransferase; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: sus:Acid_4410 arsenite S-adenosylmethyltransferase; PFAM: Methyltransferase type 11; PRIAM: Arsenite methyltransferase; SPTR: Methyltransferase type 11; PFAM: Methyltransferase domain. | 0.687 |
| Toce_1588 | Toce_1730 | Toce_1588 | Toce_1730 | COGs: COG0438 Glycosyltransferase; InterProIPR001296:IPR013216:IPR001173:IPR019734:IPR 013026:IPR000276; KEGG: tnp:Tnap_0554 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; Methyltransferase type 11; glycosyl transferase group 1; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase family 2; PFAM: Methyltransferase domain; Glycosyl transferases group 1; Glycosyl transferase family 2. | Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: hmo:HM1_1960 heptaprenyl diphosphate synthase component II, putative; PFAM: Polyprenyl synthetase; SPTR: Heptaprenyl diphosphate synthase component ii, putative; PFAM: Polyprenyl synthetase; TIGRFAM: heptaprenyl diphosphate synthase component II; Belongs to the FPP/GGPP synthase family. | 0.680 |
| Toce_1588 | ispH | Toce_1588 | Toce_1156 | COGs: COG0438 Glycosyltransferase; InterProIPR001296:IPR013216:IPR001173:IPR019734:IPR 013026:IPR000276; KEGG: tnp:Tnap_0554 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; Methyltransferase type 11; glycosyl transferase group 1; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase family 2; PFAM: Methyltransferase domain; Glycosyl transferases group 1; Glycosyl transferase family 2. | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.699 |
| Toce_1728 | Toce_1551 | Toce_1728 | Toce_1551 | UbiA prenyltransferase; COGs: COG1575 1 4-dihydroxy-2-naphthoate octaprenyltransferase; InterPro IPR000537:IPR005479; KEGG: tte:TTE2481 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: 1,4-dihydroxy-2-naphthoate octaprenyltransferase. | UbiA prenyltransferase; COGs: COG1575 1 4-dihydroxy-2-naphthoate octaprenyltransferase; InterPro IPR000537; KEGG: cth:Cthe_3041 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: UbiA prenyltransferase; PFAM: UbiA prenyltransferase family. | 0.925 |
| Toce_1728 | Toce_1729 | Toce_1728 | Toce_1729 | UbiA prenyltransferase; COGs: COG1575 1 4-dihydroxy-2-naphthoate octaprenyltransferase; InterPro IPR000537:IPR005479; KEGG: tte:TTE2481 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: 1,4-dihydroxy-2-naphthoate octaprenyltransferase. | FMN-binding domain protein; COGs: COG4939 Major membrane immunogen membrane-anchored lipoprotein; InterPro IPR007329; KEGG: lsg:lse_2542 lipoprotein, putative; PFAM: FMN-binding domain protein; SPTR: Lmo2637 protein; PFAM: FMN-binding domain. | 0.787 |
| Toce_1728 | Toce_1730 | Toce_1728 | Toce_1730 | UbiA prenyltransferase; COGs: COG1575 1 4-dihydroxy-2-naphthoate octaprenyltransferase; InterPro IPR000537:IPR005479; KEGG: tte:TTE2481 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: 1,4-dihydroxy-2-naphthoate octaprenyltransferase. | Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: hmo:HM1_1960 heptaprenyl diphosphate synthase component II, putative; PFAM: Polyprenyl synthetase; SPTR: Heptaprenyl diphosphate synthase component ii, putative; PFAM: Polyprenyl synthetase; TIGRFAM: heptaprenyl diphosphate synthase component II; Belongs to the FPP/GGPP synthase family. | 0.704 |
| Toce_1728 | Toce_1731 | Toce_1728 | Toce_1731 | UbiA prenyltransferase; COGs: COG1575 1 4-dihydroxy-2-naphthoate octaprenyltransferase; InterPro IPR000537:IPR005479; KEGG: tte:TTE2481 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: 1,4-dihydroxy-2-naphthoate octaprenyltransferase. | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG1252 NADH dehydrogenase FAD-containing subunit; InterPro IPR013027:IPR011637; KEGG: hor:Hore_14860 NADH dehydrogenase, FAD-containing subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; DoxX family protein; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; DoxX. | 0.723 |
| Toce_1729 | Toce_1551 | Toce_1729 | Toce_1551 | FMN-binding domain protein; COGs: COG4939 Major membrane immunogen membrane-anchored lipoprotein; InterPro IPR007329; KEGG: lsg:lse_2542 lipoprotein, putative; PFAM: FMN-binding domain protein; SPTR: Lmo2637 protein; PFAM: FMN-binding domain. | UbiA prenyltransferase; COGs: COG1575 1 4-dihydroxy-2-naphthoate octaprenyltransferase; InterPro IPR000537; KEGG: cth:Cthe_3041 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: UbiA prenyltransferase; PFAM: UbiA prenyltransferase family. | 0.719 |
| Toce_1729 | Toce_1728 | Toce_1729 | Toce_1728 | FMN-binding domain protein; COGs: COG4939 Major membrane immunogen membrane-anchored lipoprotein; InterPro IPR007329; KEGG: lsg:lse_2542 lipoprotein, putative; PFAM: FMN-binding domain protein; SPTR: Lmo2637 protein; PFAM: FMN-binding domain. | UbiA prenyltransferase; COGs: COG1575 1 4-dihydroxy-2-naphthoate octaprenyltransferase; InterPro IPR000537:IPR005479; KEGG: tte:TTE2481 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: 1,4-dihydroxy-2-naphthoate octaprenyltransferase. | 0.787 |
| Toce_1729 | Toce_1730 | Toce_1729 | Toce_1730 | FMN-binding domain protein; COGs: COG4939 Major membrane immunogen membrane-anchored lipoprotein; InterPro IPR007329; KEGG: lsg:lse_2542 lipoprotein, putative; PFAM: FMN-binding domain protein; SPTR: Lmo2637 protein; PFAM: FMN-binding domain. | Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: hmo:HM1_1960 heptaprenyl diphosphate synthase component II, putative; PFAM: Polyprenyl synthetase; SPTR: Heptaprenyl diphosphate synthase component ii, putative; PFAM: Polyprenyl synthetase; TIGRFAM: heptaprenyl diphosphate synthase component II; Belongs to the FPP/GGPP synthase family. | 0.745 |
| Toce_1729 | Toce_1731 | Toce_1729 | Toce_1731 | FMN-binding domain protein; COGs: COG4939 Major membrane immunogen membrane-anchored lipoprotein; InterPro IPR007329; KEGG: lsg:lse_2542 lipoprotein, putative; PFAM: FMN-binding domain protein; SPTR: Lmo2637 protein; PFAM: FMN-binding domain. | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG1252 NADH dehydrogenase FAD-containing subunit; InterPro IPR013027:IPR011637; KEGG: hor:Hore_14860 NADH dehydrogenase, FAD-containing subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; DoxX family protein; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; DoxX. | 0.837 |
| Toce_1730 | Toce_0607 | Toce_1730 | Toce_0607 | Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: hmo:HM1_1960 heptaprenyl diphosphate synthase component II, putative; PFAM: Polyprenyl synthetase; SPTR: Heptaprenyl diphosphate synthase component ii, putative; PFAM: Polyprenyl synthetase; TIGRFAM: heptaprenyl diphosphate synthase component II; Belongs to the FPP/GGPP synthase family. | Arsenite methyltransferase; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: sus:Acid_4410 arsenite S-adenosylmethyltransferase; PFAM: Methyltransferase type 11; PRIAM: Arsenite methyltransferase; SPTR: Methyltransferase type 11; PFAM: Methyltransferase domain. | 0.532 |