Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Toce_1737COGs: COG0388 amidohydrolase; InterPro IPR003010:IPR001110; KEGG: gym:GYMC10_2272 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: Carbon-nitrogen hydrolase. (268 aa)    
Predicted Functional Partners:
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
 
  
 0.789
Toce_1740
ABC transporter related protein; COGs: COG4586 ABC-type uncharacterized transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: sth:STH1197 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter ATP-binding protein; PFAM: ABC transporter.
  
    0.662
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.660
Toce_1738
Protein of unknown function DUF990; COGs: COG3694 ABC-type uncharacterized transport system permease component; InterPro IPR010390; KEGG: sth:STH1199 hypothetical protein; PFAM: protein of unknown function DUF990; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF990).
       0.658
Toce_1739
Protein of unknown function DUF990; COGs: COG4587 ABC-type uncharacterized transport system permease component; InterPro IPR010390; KEGG: pjd:Pjdr2_3967 protein of unknown function DUF990; PFAM: protein of unknown function DUF990; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF990).
       0.658
Toce_2243
Peptidase M1 membrane alanine aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR014782; KEGG: tte:TTE2694 aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; SPTR: Aminopeptidase N; PFAM: Peptidase family M1.
   
 0.648
dapL
LL-diaminopimelate aminotransferase apoenzyme; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate.
 
  
 0.639
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
   
 0.634
Toce_0592
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
    
 0.608
cinA
Competence/damage-inducible protein cinA; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR001453:IPR008136:IPR008135; KEGG: dtu:Dtur_0064 competence/damage-inducible protein CinA; PFAM: CinA domain protein; molybdopterin binding domain; SPTR: CinA-like protein; TIGRFAM: competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor [...]
  
  
 0.588
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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