STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Toce_1759TrpR like protein, YerC/YecD; COGs: COG4496 conserved hypothetical protein; InterPro IPR013368:IPR000831; KEGG: dae:Dtox_0748 TrpR like protein, YerC/YecD; PFAM: Trp repressor; SPTR: TrpR like protein, YerC/YecD; TIGRFAM: TrpR like protein, YerC/YecD; PFAM: Trp repressor protein; TIGRFAM: TrpR-related protein YerC/YecD; trp operon repressor, proteobacterial. (102 aa)    
Predicted Functional Partners:
Toce_1758
COGs: COG0210 Superfamily I DNA and RNA helicase; InterProIPR005751:IPR000212:IPR014016:IPR014017:IPR 005829; KEGG: cth:Cthe_2876 ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; SPTR: ATP-dependent DNA helicase PcrA; TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; ATP-dependent DNA helicase PcrA.
       0.718
Toce_1760
Dipeptidase; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR010964:IPR002933:IPR011650:IPR001261; KEGG: tpd:Teth39_0750 dipeptidase PepV; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; TIGRFAM: dipeptidase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: dipeptidase, putative.
       0.705
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
       0.643
Toce_1762
UspA domain protein; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR006016; KEGG: tpd:Teth39_0454 osmosensitive K+ channel histidine kinase-like protein; PFAM: UspA domain protein; SPTR: UspA domain protein; PFAM: Universal stress protein family.
  
    0.517
Toce_1761
InterPro IPR000326:IPR001011; KEGG: tit:Thit_2198 phosphoesterase PA-phosphatase related protein; PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; SPTR: Phosphoesterase PA-phosphatase related protein; PFAM: PAP2 superfamily.
       0.501
Toce_1756
KEGG: kol:Kole_1817 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.475
Toce_0923
KEGG: amt:Amet_3028 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3048).
  
    0.404
Toce_1807
Transcriptional regulator, CdaR; COGs: COG3835 Sugar diacid utilization regulator; InterPro IPR002197; KEGG: ate:Athe_1802 transcriptional regulator, CdaR; PFAM: helix-turn-helix Fis-type; SPTR: Transcriptional regulator, CdaR.
  
     0.401
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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