| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Toce_0325 | Toce_1760 | Toce_0325 | Toce_1760 | Transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: gwc:GWCH70_2215 transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain. | Dipeptidase; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR010964:IPR002933:IPR011650:IPR001261; KEGG: tpd:Teth39_0750 dipeptidase PepV; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; TIGRFAM: dipeptidase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: dipeptidase, putative. | 0.629 |
| Toce_1758 | Toce_1759 | Toce_1758 | Toce_1759 | COGs: COG0210 Superfamily I DNA and RNA helicase; InterProIPR005751:IPR000212:IPR014016:IPR014017:IPR 005829; KEGG: cth:Cthe_2876 ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; SPTR: ATP-dependent DNA helicase PcrA; TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; ATP-dependent DNA helicase PcrA. | TrpR like protein, YerC/YecD; COGs: COG4496 conserved hypothetical protein; InterPro IPR013368:IPR000831; KEGG: dae:Dtox_0748 TrpR like protein, YerC/YecD; PFAM: Trp repressor; SPTR: TrpR like protein, YerC/YecD; TIGRFAM: TrpR like protein, YerC/YecD; PFAM: Trp repressor protein; TIGRFAM: TrpR-related protein YerC/YecD; trp operon repressor, proteobacterial. | 0.718 |
| Toce_1758 | Toce_1760 | Toce_1758 | Toce_1760 | COGs: COG0210 Superfamily I DNA and RNA helicase; InterProIPR005751:IPR000212:IPR014016:IPR014017:IPR 005829; KEGG: cth:Cthe_2876 ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; SPTR: ATP-dependent DNA helicase PcrA; TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; ATP-dependent DNA helicase PcrA. | Dipeptidase; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR010964:IPR002933:IPR011650:IPR001261; KEGG: tpd:Teth39_0750 dipeptidase PepV; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; TIGRFAM: dipeptidase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: dipeptidase, putative. | 0.619 |
| Toce_1758 | Toce_1762 | Toce_1758 | Toce_1762 | COGs: COG0210 Superfamily I DNA and RNA helicase; InterProIPR005751:IPR000212:IPR014016:IPR014017:IPR 005829; KEGG: cth:Cthe_2876 ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; SPTR: ATP-dependent DNA helicase PcrA; TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; ATP-dependent DNA helicase PcrA. | UspA domain protein; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR006016; KEGG: tpd:Teth39_0454 osmosensitive K+ channel histidine kinase-like protein; PFAM: UspA domain protein; SPTR: UspA domain protein; PFAM: Universal stress protein family. | 0.455 |
| Toce_1759 | Toce_1758 | Toce_1759 | Toce_1758 | TrpR like protein, YerC/YecD; COGs: COG4496 conserved hypothetical protein; InterPro IPR013368:IPR000831; KEGG: dae:Dtox_0748 TrpR like protein, YerC/YecD; PFAM: Trp repressor; SPTR: TrpR like protein, YerC/YecD; TIGRFAM: TrpR like protein, YerC/YecD; PFAM: Trp repressor protein; TIGRFAM: TrpR-related protein YerC/YecD; trp operon repressor, proteobacterial. | COGs: COG0210 Superfamily I DNA and RNA helicase; InterProIPR005751:IPR000212:IPR014016:IPR014017:IPR 005829; KEGG: cth:Cthe_2876 ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; SPTR: ATP-dependent DNA helicase PcrA; TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; ATP-dependent DNA helicase PcrA. | 0.718 |
| Toce_1759 | Toce_1760 | Toce_1759 | Toce_1760 | TrpR like protein, YerC/YecD; COGs: COG4496 conserved hypothetical protein; InterPro IPR013368:IPR000831; KEGG: dae:Dtox_0748 TrpR like protein, YerC/YecD; PFAM: Trp repressor; SPTR: TrpR like protein, YerC/YecD; TIGRFAM: TrpR like protein, YerC/YecD; PFAM: Trp repressor protein; TIGRFAM: TrpR-related protein YerC/YecD; trp operon repressor, proteobacterial. | Dipeptidase; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR010964:IPR002933:IPR011650:IPR001261; KEGG: tpd:Teth39_0750 dipeptidase PepV; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; TIGRFAM: dipeptidase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: dipeptidase, putative. | 0.705 |
| Toce_1759 | Toce_1762 | Toce_1759 | Toce_1762 | TrpR like protein, YerC/YecD; COGs: COG4496 conserved hypothetical protein; InterPro IPR013368:IPR000831; KEGG: dae:Dtox_0748 TrpR like protein, YerC/YecD; PFAM: Trp repressor; SPTR: TrpR like protein, YerC/YecD; TIGRFAM: TrpR like protein, YerC/YecD; PFAM: Trp repressor protein; TIGRFAM: TrpR-related protein YerC/YecD; trp operon repressor, proteobacterial. | UspA domain protein; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR006016; KEGG: tpd:Teth39_0454 osmosensitive K+ channel histidine kinase-like protein; PFAM: UspA domain protein; SPTR: UspA domain protein; PFAM: Universal stress protein family. | 0.517 |
| Toce_1760 | Toce_0325 | Toce_1760 | Toce_0325 | Dipeptidase; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR010964:IPR002933:IPR011650:IPR001261; KEGG: tpd:Teth39_0750 dipeptidase PepV; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; TIGRFAM: dipeptidase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: dipeptidase, putative. | Transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: gwc:GWCH70_2215 transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain. | 0.629 |
| Toce_1760 | Toce_1758 | Toce_1760 | Toce_1758 | Dipeptidase; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR010964:IPR002933:IPR011650:IPR001261; KEGG: tpd:Teth39_0750 dipeptidase PepV; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; TIGRFAM: dipeptidase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: dipeptidase, putative. | COGs: COG0210 Superfamily I DNA and RNA helicase; InterProIPR005751:IPR000212:IPR014016:IPR014017:IPR 005829; KEGG: cth:Cthe_2876 ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; SPTR: ATP-dependent DNA helicase PcrA; TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; ATP-dependent DNA helicase PcrA. | 0.619 |
| Toce_1760 | Toce_1759 | Toce_1760 | Toce_1759 | Dipeptidase; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR010964:IPR002933:IPR011650:IPR001261; KEGG: tpd:Teth39_0750 dipeptidase PepV; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; TIGRFAM: dipeptidase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: dipeptidase, putative. | TrpR like protein, YerC/YecD; COGs: COG4496 conserved hypothetical protein; InterPro IPR013368:IPR000831; KEGG: dae:Dtox_0748 TrpR like protein, YerC/YecD; PFAM: Trp repressor; SPTR: TrpR like protein, YerC/YecD; TIGRFAM: TrpR like protein, YerC/YecD; PFAM: Trp repressor protein; TIGRFAM: TrpR-related protein YerC/YecD; trp operon repressor, proteobacterial. | 0.705 |
| Toce_1760 | Toce_1762 | Toce_1760 | Toce_1762 | Dipeptidase; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR010964:IPR002933:IPR011650:IPR001261; KEGG: tpd:Teth39_0750 dipeptidase PepV; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; TIGRFAM: dipeptidase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: dipeptidase, putative. | UspA domain protein; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR006016; KEGG: tpd:Teth39_0454 osmosensitive K+ channel histidine kinase-like protein; PFAM: UspA domain protein; SPTR: UspA domain protein; PFAM: Universal stress protein family. | 0.602 |
| Toce_1760 | Toce_1933 | Toce_1760 | Toce_1933 | Dipeptidase; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR010964:IPR002933:IPR011650:IPR001261; KEGG: tpd:Teth39_0750 dipeptidase PepV; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; TIGRFAM: dipeptidase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: dipeptidase, putative. | Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR001131:IPR001714:IPR000587:IPR000994; KEGG: cbl:CLK_3532 M24 family metallopeptidase; PFAM: peptidase M24; creatinase; SPTR: Peptidase M24; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain. | 0.605 |
| Toce_1760 | Toce_2243 | Toce_1760 | Toce_2243 | Dipeptidase; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR010964:IPR002933:IPR011650:IPR001261; KEGG: tpd:Teth39_0750 dipeptidase PepV; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; TIGRFAM: dipeptidase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: dipeptidase, putative. | Peptidase M1 membrane alanine aminopeptidase; COGs: COG0308 Aminopeptidase N; InterPro IPR014782; KEGG: tte:TTE2694 aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; SPTR: Aminopeptidase N; PFAM: Peptidase family M1. | 0.614 |
| Toce_1760 | argG | Toce_1760 | Toce_0156 | Dipeptidase; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR010964:IPR002933:IPR011650:IPR001261; KEGG: tpd:Teth39_0750 dipeptidase PepV; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; TIGRFAM: dipeptidase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: dipeptidase, putative. | COGs: COG0137 Argininosuccinate synthase; InterPro IPR001518:IPR018223; KEGG: gyc:GYMC61_0760 argininosuccinate synthase; PFAM: argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: Argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.622 |
| Toce_1760 | dapF | Toce_1760 | Toce_1018 | Dipeptidase; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR010964:IPR002933:IPR011650:IPR001261; KEGG: tpd:Teth39_0750 dipeptidase PepV; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; TIGRFAM: dipeptidase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: dipeptidase, putative. | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.949 |
| Toce_1760 | dapL | Toce_1760 | Toce_1019 | Dipeptidase; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR010964:IPR002933:IPR011650:IPR001261; KEGG: tpd:Teth39_0750 dipeptidase PepV; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; TIGRFAM: dipeptidase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: dipeptidase, putative. | LL-diaminopimelate aminotransferase apoenzyme; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. | 0.914 |
| Toce_1760 | guaB | Toce_1760 | Toce_2129 | Dipeptidase; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR010964:IPR002933:IPR011650:IPR001261; KEGG: tpd:Teth39_0750 dipeptidase PepV; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; TIGRFAM: dipeptidase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: dipeptidase, putative. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.673 |
| Toce_1762 | Toce_1758 | Toce_1762 | Toce_1758 | UspA domain protein; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR006016; KEGG: tpd:Teth39_0454 osmosensitive K+ channel histidine kinase-like protein; PFAM: UspA domain protein; SPTR: UspA domain protein; PFAM: Universal stress protein family. | COGs: COG0210 Superfamily I DNA and RNA helicase; InterProIPR005751:IPR000212:IPR014016:IPR014017:IPR 005829; KEGG: cth:Cthe_2876 ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; SPTR: ATP-dependent DNA helicase PcrA; TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; ATP-dependent DNA helicase PcrA. | 0.455 |
| Toce_1762 | Toce_1759 | Toce_1762 | Toce_1759 | UspA domain protein; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR006016; KEGG: tpd:Teth39_0454 osmosensitive K+ channel histidine kinase-like protein; PFAM: UspA domain protein; SPTR: UspA domain protein; PFAM: Universal stress protein family. | TrpR like protein, YerC/YecD; COGs: COG4496 conserved hypothetical protein; InterPro IPR013368:IPR000831; KEGG: dae:Dtox_0748 TrpR like protein, YerC/YecD; PFAM: Trp repressor; SPTR: TrpR like protein, YerC/YecD; TIGRFAM: TrpR like protein, YerC/YecD; PFAM: Trp repressor protein; TIGRFAM: TrpR-related protein YerC/YecD; trp operon repressor, proteobacterial. | 0.517 |
| Toce_1762 | Toce_1760 | Toce_1762 | Toce_1760 | UspA domain protein; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR006016; KEGG: tpd:Teth39_0454 osmosensitive K+ channel histidine kinase-like protein; PFAM: UspA domain protein; SPTR: UspA domain protein; PFAM: Universal stress protein family. | Dipeptidase; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR010964:IPR002933:IPR011650:IPR001261; KEGG: tpd:Teth39_0750 dipeptidase PepV; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; TIGRFAM: dipeptidase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: dipeptidase, putative. | 0.602 |