Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Toce_1762UspA domain protein; COGs: COG2205 Osmosensitive K+ channel histidine kinase; InterPro IPR006016; KEGG: tpd:Teth39_0454 osmosensitive K+ channel histidine kinase-like protein; PFAM: UspA domain protein; SPTR: UspA domain protein; PFAM: Universal stress protein family. (136 aa)    
Predicted Functional Partners:
Toce_1761
InterPro IPR000326:IPR001011; KEGG: tit:Thit_2198 phosphoesterase PA-phosphatase related protein; PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; SPTR: Phosphoesterase PA-phosphatase related protein; PFAM: PAP2 superfamily.
     
 0.769
Toce_2232
InterPro IPR018604; KEGG: tit:Thit_2308 protein of unknown function YycH; PFAM: Protein of unknown function YycH; SPTR: Putative uncharacterized protein; PFAM: YycH protein.
  
   
 0.689
luxS
Quorum-sensing autoinducer 2 (AI-2), LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
     
 0.645
Toce_0631
KEGG: tte:TTE0927 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.630
Toce_2233
YycH family protein; COGs: COG4863 conserved hypothetical protein; InterPro IPR009996; KEGG: amt:Amet_4755 hypothetical protein; PFAM: YycH family protein; SPTR: Putative uncharacterized protein; PFAM: YycH protein.
  
   
 0.611
Toce_1760
Dipeptidase; COGs: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR010964:IPR002933:IPR011650:IPR001261; KEGG: tpd:Teth39_0750 dipeptidase PepV; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; TIGRFAM: dipeptidase; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: dipeptidase, putative.
 
     0.602
Toce_0372
Diguanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160:IPR003018; KEGG: tte:TTE2335 diguanylate cyclase/phosphodiesterase; PFAM: GGDEF domain containing protein; GAF domain protein; PRIAM: Diguanylate kinase; SMART: GGDEF domain containing protein; GAF domain protein; SPTR: Diguanylate cyclase/phosphodiesterase domain 1 (GGDEF); TIGRFAM: diguanylate cyclase; PFAM: GAF domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
     
 0.594
Toce_0285
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: dae:Dtox_2625 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
  
 
 0.577
Toce_0967
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: chy:CHY_2047 DNA-binding response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: DNA-binding response regulator; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB.
  
 
 0.577
Toce_1455
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: mta:Moth_0827 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
  
 
 0.577
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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