Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Toce_1765COGs: COG1067 ATP-dependent protease; InterProIPR014251:IPR003959:IPR001984:IPR003593:IPR 008268; KEGG: drm:Dred_2560 ATPase central domain-containing protein; PFAM: AAA ATPase central domain protein; PRIAM: Endopeptidase La; SMART: AAA ATPase; SPTR: Endopeptidase La; TIGRFAM: ATP-dependent protease LonB; PFAM: ATPase family associated with various cellular activities (AAA); Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: ATP-dependent protease LonB; lon-related putative ATP-dependent protease. (555 aa)    
Predicted Functional Partners:
Toce_1321
InterPro IPR014198; KEGG: drm:Dred_1057 stage III sporulation protein SpoAB; PFAM: Sporulation stage III protein AB; SPTR: Stage III sporulation protein AB; TIGRFAM: stage III sporulation protein AB; PFAM: Stage III sporulation protein AB (spore_III_AB); TIGRFAM: stage III sporulation protein AB.
  
    0.774
lon
ATP-dependent proteinase; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.
 
  
0.703
Toce_1318
InterPro IPR014194; KEGG: dae:Dtox_2607 stage III sporulation protein AE; PFAM: Sporulation stage III protein AE; SPTR: Stage III sporulation protein AE; TIGRFAM: stage III sporulation protein AE; PFAM: Stage III sporulation protein AE (spore_III_AE); TIGRFAM: stage III sporulation protein AE.
  
    0.681
clpX
ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
  
  
 0.677
Toce_1133
KEGG: chy:CHY_0535 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.651
clpP
ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
  
  
 0.650
Toce_2262
Sporulation protein YyaC; InterPro IPR009665:IPR005080; KEGG: gyc:GYMC61_3551 sporulation protein YyaC; PFAM: protein of unknown function DUF1256; SPTR: Hypothetical conserved protein; TIGRFAM: sporulation protein YyaC; PFAM: Protein of unknown function (DUF1256); TIGRFAM: putative sporulation protein YyaC.
  
     0.635
Toce_1272
Stage II sporulation protein M; InterPro IPR014196:IPR002798; KEGG: aoe:Clos_1594 sporulation stage II protein M; PFAM: protein of unknown function DUF95 transmembrane; SPTR: Sporulation stage II protein M; TIGRFAM: stage II sporulation protein M; PFAM: Integral membrane protein DUF95; TIGRFAM: stage II sporulation protein M.
  
    0.633
Toce_0899
Membrane protein of unknown function; InterPro IPR007165; KEGG: mta:Moth_0580 hypothetical protein; PFAM: membrane protein of unknown function; SPTR: Putative uncharacterized protein; PFAM: Membrane protein of unknown function.
  
     0.632
Toce_1317
InterPro IPR014245; KEGG: amt:Amet_2497 sporulation stage III, protein AF; PFAM: Sporulation stage III protein AF; SPTR: Sporulation stage III, protein AF; TIGRFAM: stage III sporulation protein AF; PFAM: Stage III sporulation protein AF (Spore_III_AF); TIGRFAM: stage III sporulation protein AF.
  
     0.619
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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