Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Toce_1769Beta-phosphoglucomutase; COGs: COG0637 phosphatase/phosphohexomutase; InterProIPR010972:IPR010976:IPR006402:IPR005834:IPR 005833; KEGG: tte:TTE0802 phosphatase/phosphohexomutase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Predicted phosphatase/phosphohexomutase; TIGRFAM: beta-phosphoglucomutase; beta-phosphoglucomutase family hydrolase; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: beta-phosphoglucomutase; haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; beta-phosphog [...] (222 aa)    
Predicted Functional Partners:
Toce_1770
Glycoside hydrolase family 65 central catalytic; COGs: COG1554 Trehalose and maltose hydrolase (possible phosphorylase); InterPro IPR005196:IPR005195:IPR005194:IPR017045; KEGG: tpd:Teth39_1512 kojibiose phosphorylase; PFAM: glycoside hydrolase family 65 central catalytic; glycoside hydrolase family 65 domain protein; SPTR: Kojibiose phosphorylase; PFAM: Glycosyl hydrolase family 65, C-terminal domain; Glycosyl hydrolase family 65 central catalytic domain; Glycosyl hydrolase family 65, N-terminal domain.
 
 0.999
Toce_1051
Thioesterase superfamily protein; InterPro IPR001034:IPR006683:IPR017275; KEGG: tit:Thit_1285 protein for fatty acid biosynthesis transcriptional regulation; PFAM: thioesterase superfamily protein; regulatory protein DeoR; SPTR: Protein for fatty acid biosynthesis transcriptional regulation; manually curated; PFAM: Thioesterase superfamily; DeoR-like helix-turn-helix domain.
  
  
 0.683
Toce_1588
COGs: COG0438 Glycosyltransferase; InterProIPR001296:IPR013216:IPR001173:IPR019734:IPR 013026:IPR000276; KEGG: tnp:Tnap_0554 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; Methyltransferase type 11; glycosyl transferase group 1; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase family 2; PFAM: Methyltransferase domain; Glycosyl transferases group 1; Glycosyl transferase family 2.
  
  
 0.671
Toce_1771
Carbohydrate ABC transporter substrate-binding protein, CUT1 family; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: tit:Thit_0763 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein.
 
   
 0.630
Toce_1469
Domain of unknown function DUF1730; COGs: COG1600 Uncharacterized Fe-S protein; InterPro IPR013542:IPR017896:IPR017900; KEGG: gyc:GYMC61_1368 iron-sulfur cluster binding protein; PFAM: domain of unknown function DUF1730; SPTR: Hypothetical conserved protein; PFAM: 4Fe-4S binding domain; Domain of unknown function (DUF1730); TIGRFAM: iron-sulfur cluster binding protein, putative.
      0.591
Toce_1773
Carbohydrate ABC transporter membrane protein 1, CUT1 family; COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: tpd:Teth39_1515 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.
  
  
 0.570
Toce_1772
Carbohydrate ABC transporter membrane protein 2, CUT1 family; COGs: COG0395 ABC-type sugar transport system permease component; InterPro IPR000515; KEGG: tpd:Teth39_1514 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.
     
 0.525
Toce_1774
Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: tte:TTE0803 transcriptional regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: Transcriptional regulator; PFAM: Bacterial regulatory proteins, lacI family; family; TIGRFAM: catabolite control protein A.
 
   
 0.521
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.486
Toce_1741
Alpha amylase catalytic region; COGs: COG0366 Glycosidase; InterPro IPR006047:IPR006589; KEGG: ate:Athe_0165 alpha amylase catalytic region; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: Alpha amylase catalytic region; PFAM: Alpha amylase, catalytic domain.
  
  
 0.456
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (16%) [HD]