Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
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textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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Toce_1777Peptidase S8 and S53 subtilisin kexin sedolisin; COGs: COG1404 Subtilisin-like serine protease; InterPro IPR010259:IPR000209:IPR007280:IPR018247; KEGG: tex:Teth514_2192 peptidase S8 and S53, subtilisin, kexin, sedolisin; PFAM: peptidase S8 and S53 subtilisin kexin sedolisin; proteinase inhibitor I9 subtilisin propeptide; peptidase domain protein; SPTR: Peptidase S8 and S53, subtilisin, kexin, sedolisin; PFAM: Bacterial pre-peptidase C-terminal domain; Peptidase inhibitor I9; Subtilase family. (573 aa)    
Predicted Functional Partners:
Toce_1771
Carbohydrate ABC transporter substrate-binding protein, CUT1 family; COGs: COG1653 ABC-type sugar transport system periplasmic component; InterPro IPR006059; KEGG: tit:Thit_0763 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein.
 
     0.653
Toce_0496
S-layer domain protein; InterPro IPR001119; KEGG: gym:GYMC10_1663 S-layer domain protein; PFAM: S-layer domain protein; SPTR: S-layer associated multidomain endoglucanase; PFAM: S-layer homology domain.
 
 
 0.585
Toce_1032
COGs: COG0515 Serine/threonine protein kinase; InterProIPR020635:IPR002290:IPR005543:IPR017442:IPR 017441:IPR008271:IPR000719; KEGG: tpd:Teth39_1313 serine/threonine protein kinase with PASTA sensor(s); PFAM: Serine/threonine-protein kinase-like domain; PASTA domain containing protein; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; PASTA domain containing protein; SPTR: Serine/threonine protein kinase with PASTA sensor(S); PFAM: Protein kinase domain; PASTA domain.
 
 
 
 0.525
dinB
DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
  
 
 0.484
Toce_0881
ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG0474 Cation transport ATPase; InterProIPR001757:IPR018303:IPR006069:IPR004014:IPR 008250:IPR005834:IPR006068; KEGG: cpo:COPRO5265_1364 cation-transporting ATPase; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Cation-transporting ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; Cation transporter/ATPase, N-terminus; haloacid dehaloge [...]
   
 
 0.439
Toce_1342
ATPase, P-type (transporting), HAD superfamily, subfamily IC; COGs: COG0474 Cation transport ATPase; InterProIPR001757:IPR004014:IPR008250:IPR005834:IPR 006068:IPR018303:IPR000695; KEGG: tpd:Teth39_0231 calcium-translocating P-type ATPase, PMCA-type; PFAM: E1-E2 ATPase-associated domain protein; cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Calcium-translocating P-type ATPase, PMCA-type; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; Cation transporter/ [...]
   
 
 0.439
Toce_1223
DNA translocase FtsK; COGs: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related protein; InterPro IPR003593:IPR002543:IPR018541; KEGG: pth:PTH_1293 DNA segregation ATPase FtsK/SpoIIIE and related proteins; PFAM: cell divisionFtsK/SpoIIIE; DNA translocase ftsK gamma; SMART: AAA ATPase; SPTR: DNA segregation ATPase FtsK/SpoIIIE and related proteins; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family.
  
 
 0.437
Toce_1776
KEGG: cbe:Cbei_3683 cell wall-associated hydrolase-like protein; SPTR: Cell wall-associated hydrolase-like protein; PFAM: Orthopoxvirus protein of unknown function (DUF830).
       0.433
Toce_0347
S-layer domain protein; InterPro IPR001119:IPR001330; KEGG: pth:PTH_1483 hypothetical protein; PFAM: S-layer domain protein; Prenyltransferase/squalene oxidase; SPTR: Hypothetical membrane protein; PFAM: Prenyltransferase and squalene oxidase repeat; S-layer homology domain.
  
 
 0.413
Toce_0497
S-layer domain protein; InterPro IPR001119; KEGG: tex:Teth514_1781 alpha amylase, catalytic region; PFAM: S-layer domain protein; SPTR: Alpha amylase, catalytic region; PFAM: S-layer homology domain.
  
 
 0.413
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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