Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Toce_1805YheO domain protein; COGs: COG2964 conserved hypothetical protein; InterPro IPR013559; KEGG: chy:CHY_2461 PAC domain-containing protein; PFAM: YheO domain protein; SPTR: Putative PAC domain protein; PFAM: YheO-like PAS domain. (227 aa)    
Predicted Functional Partners:
Toce_1803
L-threonine ammonia-lyase; COGs: COG1171 Threonine dehydratase; InterPro IPR005789:IPR001926:IPR002912:IPR000634; KEGG: chy:CHY_2459 threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; amino acid-binding ACT domain protein; SPTR: Threonine dehydratase; TIGRFAM: threonine dehydratase; PFAM: ACT domain; Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine ammonia-lyase, biosynthetic, long form; threonine dehydratase, medium form.
       0.711
Toce_1804
Endoribonuclease L-PSP; COGs: COG0251 Putative translation initiation inhibitor yjgF family; InterPro IPR006056:IPR006175; KEGG: tit:Thit_1447 endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; SPTR: Putative endoribonuclease L-PSP; TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; TIGRFAM: endoribonuclease L-PSP, putative.
     
 0.705
Toce_1802
COGs: COG1760 L-serine deaminase; InterPro IPR004643:IPR005131:IPR002912; KEGG: tit:Thit_0968 L-serine dehydratase, iron-sulfur-dependent, beta subunit; PFAM: serine dehydratase beta chain; amino acid-binding ACT domain protein; PRIAM: L-serine ammonia-lyase; SPTR: L-serine dehydratase, iron-sulfur-dependent, beta subunit; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit; manually curated; PFAM: ACT domain; Serine dehydratase beta chain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, beta subunit.
 
    0.660
Toce_1801
COGs: COG1760 L-serine deaminase; InterPro IPR004642:IPR005130; KEGG: cno:NT01CX_1254 L-serine dehydratase, iron-sulfur-dependent, alpha subunit; PFAM: serine dehydratase alpha chain; PRIAM: L-serine ammonia-lyase; SPTR: L-serine dehydratase, iron-sulfur-dependent, alpha subunit; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, alpha subunit; PFAM: Serine dehydratase alpha chain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, alpha subunit.
 
    0.651
Toce_1806
Carbohydrate ABC transporter ATP-binding protein, CUT1 family; COGs: COG3839 ABC-type sugar transport systems ATPase components; InterPro IPR003439:IPR005116:IPR003593:IPR017871; KEGG: tte:TTE1979 ABC-type sugar/spermidine/putrescine/iron/thiamine transport systems, ATPase component; PFAM: ABC transporter related; TOBE domain protein; SMART: AAA ATPase; SPTR: ABC-type sugar/spermidine/putrescine/iron/thiamine transport systems, ATPase component; PFAM: ABC transporter; TOBE domain.
       0.481
Toce_1800
COGs: COG1301 Na+/H+-dicarboxylate symporter; InterPro IPR001991; KEGG: drm:Dred_0908 sodium:dicarboxylate symporter; PFAM: sodium:dicarboxylate symporter; SPTR: Serine/threonine transporter; PFAM: Sodium:dicarboxylate symporter family; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
       0.439
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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