Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Toce_1843Na+/solute symporter; COGs: COG4145 Na+/panthothenate symporter; InterPro IPR001734; KEGG: amt:Amet_2980 Na+/solute symporter; PFAM: Na+/solute symporter; SPTR: Na+/solute symporter; PFAM: Sodium:solute symporter family; TIGRFAM: SSS sodium solute transporter superfamily; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (487 aa)    
Predicted Functional Partners:
Toce_1844
COGs: COG5002 Signal transduction histidine kinase; InterProIPR003660:IPR003661:IPR003594:IPR004358:IPR 005467; KEGG: amt:Amet_2979 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: Sensor protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
     0.856
Toce_1841
COGs: COG2049 Allophanate hydrolase subunit 1; InterPro IPR010016:IPR003833; KEGG: tpd:Teth39_1158 allophanate hydrolase subunit 1; PFAM: Allophanate hydrolase subunit 1; SMART: Allophanate hydrolase subunit 1; SPTR: Allophanate hydrolase subunit 1; PFAM: Allophanate hydrolase subunit 1; TIGRFAM: conserved hypothetical protein TIGR00370.
 
   
 0.633
Toce_1840
Urea amidolyase related protein; COGs: COG1984 Allophanate hydrolase subunit 2; InterPro IPR003778; KEGG: tpd:Teth39_1159 UreA amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; PRIAM: Urea carboxylase; SMART: Allophanate hydrolase subunit 2; SPTR: Urea amidolyase related protein; TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; TIGRFAM: biotin-dependent carboxylase uncharacterized domain.
 
   
 0.610
pxpA
LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
 
     0.606
Toce_0361
Sodium:neurotransmitter symporter; COGs: COG0733 Na+-dependent transporter of the SNF family; InterPro IPR000175; KEGG: amt:Amet_0580 sodium:neurotransmitter symporter; PFAM: sodium:neurotransmitter symporter; SPTR: Transporter; PFAM: Sodium:neurotransmitter symporter family.
 
  
 0.596
Toce_1845
Two component, sigma54 specific, transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR001789:IPR002078:IPR002197:IPR020441:IPR 003593; KEGG: gsu:GSU2915 sigma-54 dependent DNA-binding response regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase; SPTR: Sigma-54 dependent DNA-binding response regulator; PFAM: Response regulator receiver domain; Bacterial regulatory pr [...]
     
 0.595
Toce_0046
Pur operon repressor; COGs: COG0503 Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein; InterPro IPR010078:IPR015265:IPR000836; KEGG: aoe:Clos_2648 pur operon repressor; PFAM: purine repressor; phosphoribosyltransferase; SPTR: Purine operon repressor, PurR; TIGRFAM: pur operon repressor; PFAM: Phosphoribosyl transferase domain; Bacterial purine repressor, N-terminal; TIGRFAM: pur operon repressor, Bacillus subtilis type.
   
  
 0.522
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
  
 0.522
Toce_1608
Domain of unknown function DUF1850; COGs: COG4729 conserved hypothetical protein; InterPro IPR015001; KEGG: drm:Dred_3212 hypothetical protein; PFAM: Domain of unknown function DUF1850; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF1850).
  
     0.447
Toce_1451
Amino acid carrier protein; COGs: COG1115 Na+/alanine symporter; InterPro IPR001463; KEGG: tex:Teth514_0910 amino acid carrier protein; PFAM: sodium:alanine symporter; SPTR: Amino acid carrier protein; TIGRFAM: amino acid carrier protein; PFAM: Sodium:alanine symporter family; TIGRFAM: amino acid carrier protein.
  
   
 0.434
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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