STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Toce_1876PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR002173:IPR011611; KEGG: ypz:YPZ3_1906 putative sugar kinase; PFAM: PfkB domain protein; SPTR: Putative sugar kinase; PFAM: pfkB family carbohydrate kinase. (319 aa)    
Predicted Functional Partners:
xylB
Xylulokinase; COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018483:IPR006000:IPR018484:IPR018485; KEGG: tpd:Teth39_2059 xylulokinase; PFAM: Carbohydrate kinase, FGGY-like; SPTR: Xylulokinase; TIGRFAM: xylulokinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: D-xylulose kinase.
 
  
 0.911
Toce_1875
COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771; KEGG: str:Sterm_0504 ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Putative uncharacterized protein; TIGRFAM: ketose-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases.
 
  
 0.885
rbsA
Monosaccharide ABC transporter ATP-binding protein, CUT2 family; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
 
  
 0.854
Toce_1877
D-lyxose ketol-isomerase; COGs: COG3822 ABC-type sugar transport system auxiliary component; KEGG: cce:Ccel_0320 YdaE; PRIAM: D-lyxose ketol-isomerase; SPTR: YdaE; PFAM: Protein of unknown function (DUF1498).
 
   
 0.849
Toce_1872
Monosaccharide ABC transporter membrane protein, CUT2 family; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: tte:TTE0764 ribose/xylose/arabinose/galactoside ABC-type transporter permease; PFAM: inner-membrane translocator; SPTR: Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; PFAM: Branched-chain amino acid transport system / permease component.
 
  
 0.841
Toce_1871
Periplasmic binding protein/LacI transcriptional regulator; COGs: COG1879 ABC-type sugar transport system periplasmic component; InterPro IPR001761; KEGG: tte:TTE0765 periplasmic sugar-binding proteins; PFAM: periplasmic binding protein/LacI transcriptional regulator; SPTR: Periplasmic sugar-binding proteins; PFAM: family.
 
  
 0.799
Toce_1878
Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: tte:TTE0760 transcriptional regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: Transcriptional regulator; PFAM: Bacterial regulatory proteins, lacI family; family.
 
  
 0.789
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.782
Toce_1750
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
    
 
 0.764
Toce_1870
KEGG: elf:LF82_p516 hypothetical protein; SPTR: Putative uncharacterized protein.
 
  
 0.731
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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