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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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Toce_1878Transcriptional regulator, LacI family; COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: tte:TTE0760 transcriptional regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: Transcriptional regulator; PFAM: Bacterial regulatory proteins, lacI family; family. (343 aa)    
Predicted Functional Partners:
xylB
Xylulokinase; COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018483:IPR006000:IPR018484:IPR018485; KEGG: tpd:Teth39_2059 xylulokinase; PFAM: Carbohydrate kinase, FGGY-like; SPTR: Xylulokinase; TIGRFAM: xylulokinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: D-xylulose kinase.
 
 
 
 0.823
Toce_0866
COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR000032:IPR005698:IPR001020:IPR002114; KEGG: tte:TTE1820 phosphotransferase system, HPr-related proteins; PFAM: phosphoryl transfer system HPr; SPTR: Phosphotransferase system, HPr-related proteins; TIGRFAM: phosphocarrier, HPr family; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family.
   
 
 0.815
Toce_0871
COGs: COG0469 Pyruvate kinase; InterProIPR001697:IPR018209:IPR015793:IPR015794:IPR 008279; KEGG: tte:TTE1815 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; SPTR: Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
   
 
 0.794
Toce_1876
PfkB domain protein; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR002173:IPR011611; KEGG: ypz:YPZ3_1906 putative sugar kinase; PFAM: PfkB domain protein; SPTR: Putative sugar kinase; PFAM: pfkB family carbohydrate kinase.
 
  
 0.789
Toce_1871
Periplasmic binding protein/LacI transcriptional regulator; COGs: COG1879 ABC-type sugar transport system periplasmic component; InterPro IPR001761; KEGG: tte:TTE0765 periplasmic sugar-binding proteins; PFAM: periplasmic binding protein/LacI transcriptional regulator; SPTR: Periplasmic sugar-binding proteins; PFAM: family.
 
  
 0.724
Toce_1872
Monosaccharide ABC transporter membrane protein, CUT2 family; COGs: COG1172 Ribose/xylose/arabinose/galactoside ABC-type transport systems permease components; InterPro IPR001851; KEGG: tte:TTE0764 ribose/xylose/arabinose/galactoside ABC-type transporter permease; PFAM: inner-membrane translocator; SPTR: Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components; PFAM: Branched-chain amino acid transport system / permease component.
 
  
 0.723
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
    
   0.688
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
   0.688
rbsA
Monosaccharide ABC transporter ATP-binding protein, CUT2 family; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family.
 
  
 0.684
Toce_1875
COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771; KEGG: str:Sterm_0504 ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Putative uncharacterized protein; TIGRFAM: ketose-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases.
   
 
 0.673
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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