| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Toce_0174 | Toce_1717 | Toce_0174 | Toce_1717 | Protein of unknown function DUF1393; COGs: COG4720 membrane protein; KEGG: aco:Amico_1479 protein of unknown function DUF1393; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1393). | Proton-coupled thiamine transporter YuaJ; COGs: COG3859 membrane protein; InterPro IPR012651; KEGG: chy:CHY_0230 proton-coupled thiamine transporter YuaJ; PFAM: thiamine transporter YuaJ; SPTR: Probable proton-coupled thiamine transporter YuaJ; TIGRFAM: proton-coupled thiamine transporter YuaJ; PFAM: Thiamine transporter protein (Thia_YuaJ); TIGRFAM: probable proton-coupled thiamine transporter YuaJ. | 0.491 |
| Toce_0174 | Toce_1895 | Toce_0174 | Toce_1895 | Protein of unknown function DUF1393; COGs: COG4720 membrane protein; KEGG: aco:Amico_1479 protein of unknown function DUF1393; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1393). | Conserved hypothetical protein; Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins; Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family. | 0.531 |
| Toce_0174 | Toce_2085 | Toce_0174 | Toce_2085 | Protein of unknown function DUF1393; COGs: COG4720 membrane protein; KEGG: aco:Amico_1479 protein of unknown function DUF1393; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1393). | COGs: COG4684 membrane protein; KEGG: tpd:Teth39_0308 membrane protein-like protein; SPTR: Membrane protein-like protein. | 0.405 |
| Toce_0174 | ecfT | Toce_0174 | Toce_0151 | Protein of unknown function DUF1393; COGs: COG4720 membrane protein; KEGG: aco:Amico_1479 protein of unknown function DUF1393; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1393). | Cobalt transport protein; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. | 0.852 |
| Toce_1695 | Toce_1893 | Toce_1695 | Toce_1893 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Peptidase M22 glycoprotease; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905; KEGG: cth:Cthe_1775 peptidase M22, glycoprotease; PFAM: peptidase M22 glycoprotease; SPTR: Putative uncharacterized protein; PFAM: Glycoprotease family. | 0.517 |
| Toce_1695 | Toce_1895 | Toce_1695 | Toce_1895 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Conserved hypothetical protein; Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins; Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family. | 0.517 |
| Toce_1695 | ribBA | Toce_1695 | Toce_1693 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.999 |
| Toce_1695 | ribH | Toce_1695 | Toce_1692 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.999 |
| Toce_1717 | Toce_0174 | Toce_1717 | Toce_0174 | Proton-coupled thiamine transporter YuaJ; COGs: COG3859 membrane protein; InterPro IPR012651; KEGG: chy:CHY_0230 proton-coupled thiamine transporter YuaJ; PFAM: thiamine transporter YuaJ; SPTR: Probable proton-coupled thiamine transporter YuaJ; TIGRFAM: proton-coupled thiamine transporter YuaJ; PFAM: Thiamine transporter protein (Thia_YuaJ); TIGRFAM: probable proton-coupled thiamine transporter YuaJ. | Protein of unknown function DUF1393; COGs: COG4720 membrane protein; KEGG: aco:Amico_1479 protein of unknown function DUF1393; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1393). | 0.491 |
| Toce_1717 | Toce_1895 | Toce_1717 | Toce_1895 | Proton-coupled thiamine transporter YuaJ; COGs: COG3859 membrane protein; InterPro IPR012651; KEGG: chy:CHY_0230 proton-coupled thiamine transporter YuaJ; PFAM: thiamine transporter YuaJ; SPTR: Probable proton-coupled thiamine transporter YuaJ; TIGRFAM: proton-coupled thiamine transporter YuaJ; PFAM: Thiamine transporter protein (Thia_YuaJ); TIGRFAM: probable proton-coupled thiamine transporter YuaJ. | Conserved hypothetical protein; Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins; Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family. | 0.615 |
| Toce_1717 | Toce_2085 | Toce_1717 | Toce_2085 | Proton-coupled thiamine transporter YuaJ; COGs: COG3859 membrane protein; InterPro IPR012651; KEGG: chy:CHY_0230 proton-coupled thiamine transporter YuaJ; PFAM: thiamine transporter YuaJ; SPTR: Probable proton-coupled thiamine transporter YuaJ; TIGRFAM: proton-coupled thiamine transporter YuaJ; PFAM: Thiamine transporter protein (Thia_YuaJ); TIGRFAM: probable proton-coupled thiamine transporter YuaJ. | COGs: COG4684 membrane protein; KEGG: tpd:Teth39_0308 membrane protein-like protein; SPTR: Membrane protein-like protein. | 0.603 |
| Toce_1717 | ecfT | Toce_1717 | Toce_0151 | Proton-coupled thiamine transporter YuaJ; COGs: COG3859 membrane protein; InterPro IPR012651; KEGG: chy:CHY_0230 proton-coupled thiamine transporter YuaJ; PFAM: thiamine transporter YuaJ; SPTR: Probable proton-coupled thiamine transporter YuaJ; TIGRFAM: proton-coupled thiamine transporter YuaJ; PFAM: Thiamine transporter protein (Thia_YuaJ); TIGRFAM: probable proton-coupled thiamine transporter YuaJ. | Cobalt transport protein; Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. | 0.643 |
| Toce_1892 | Toce_1893 | Toce_1892 | Toce_1893 | COGs: COG0456 Acetyltransferase; InterPro IPR006464:IPR000182; KEGG: bmq:BMQ_0258 ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: Ribosomal-protein (S18)-alanine acetyltransferase; TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: Acetyltransferase (GNAT) family; TIGRFAM: ribosomal-protein-alanine acetyltransferase. | Peptidase M22 glycoprotease; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905; KEGG: cth:Cthe_1775 peptidase M22, glycoprotease; PFAM: peptidase M22 glycoprotease; SPTR: Putative uncharacterized protein; PFAM: Glycoprotease family. | 0.998 |
| Toce_1892 | Toce_1894 | Toce_1892 | Toce_1894 | COGs: COG0456 Acetyltransferase; InterPro IPR006464:IPR000182; KEGG: bmq:BMQ_0258 ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: Ribosomal-protein (S18)-alanine acetyltransferase; TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: Acetyltransferase (GNAT) family; TIGRFAM: ribosomal-protein-alanine acetyltransferase. | Protein of unknown function UPF0079; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: amt:Amet_0803 hypothetical protein; PFAM: protein of unknown function UPF0079; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: conserved hypothetical nucleotide-binding protein. | 0.892 |
| Toce_1892 | Toce_1895 | Toce_1892 | Toce_1895 | COGs: COG0456 Acetyltransferase; InterPro IPR006464:IPR000182; KEGG: bmq:BMQ_0258 ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: Ribosomal-protein (S18)-alanine acetyltransferase; TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: Acetyltransferase (GNAT) family; TIGRFAM: ribosomal-protein-alanine acetyltransferase. | Conserved hypothetical protein; Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins; Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family. | 0.520 |
| Toce_1893 | Toce_1695 | Toce_1893 | Toce_1695 | Peptidase M22 glycoprotease; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905; KEGG: cth:Cthe_1775 peptidase M22, glycoprotease; PFAM: peptidase M22 glycoprotease; SPTR: Putative uncharacterized protein; PFAM: Glycoprotease family. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.517 |
| Toce_1893 | Toce_1892 | Toce_1893 | Toce_1892 | Peptidase M22 glycoprotease; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905; KEGG: cth:Cthe_1775 peptidase M22, glycoprotease; PFAM: peptidase M22 glycoprotease; SPTR: Putative uncharacterized protein; PFAM: Glycoprotease family. | COGs: COG0456 Acetyltransferase; InterPro IPR006464:IPR000182; KEGG: bmq:BMQ_0258 ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: Ribosomal-protein (S18)-alanine acetyltransferase; TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: Acetyltransferase (GNAT) family; TIGRFAM: ribosomal-protein-alanine acetyltransferase. | 0.998 |
| Toce_1893 | Toce_1894 | Toce_1893 | Toce_1894 | Peptidase M22 glycoprotease; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905; KEGG: cth:Cthe_1775 peptidase M22, glycoprotease; PFAM: peptidase M22 glycoprotease; SPTR: Putative uncharacterized protein; PFAM: Glycoprotease family. | Protein of unknown function UPF0079; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: amt:Amet_0803 hypothetical protein; PFAM: protein of unknown function UPF0079; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: conserved hypothetical nucleotide-binding protein. | 0.999 |
| Toce_1893 | Toce_1895 | Toce_1893 | Toce_1895 | Peptidase M22 glycoprotease; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905; KEGG: cth:Cthe_1775 peptidase M22, glycoprotease; PFAM: peptidase M22 glycoprotease; SPTR: Putative uncharacterized protein; PFAM: Glycoprotease family. | Conserved hypothetical protein; Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins; Belongs to the prokaryotic riboflavin transporter (P-RFT) (TC 2.A.87) family. | 0.520 |
| Toce_1894 | Toce_1892 | Toce_1894 | Toce_1892 | Protein of unknown function UPF0079; COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: amt:Amet_0803 hypothetical protein; PFAM: protein of unknown function UPF0079; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: conserved hypothetical nucleotide-binding protein. | COGs: COG0456 Acetyltransferase; InterPro IPR006464:IPR000182; KEGG: bmq:BMQ_0258 ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: Ribosomal-protein (S18)-alanine acetyltransferase; TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: Acetyltransferase (GNAT) family; TIGRFAM: ribosomal-protein-alanine acetyltransferase. | 0.892 |