STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Toce_1899COGs: COG2055 Malate/L-lactate dehydrogenase; InterPro IPR003767; KEGG: bbe:BBR47_30890 putative malate/L-sulfolactate dehydrogenase; PFAM: Malate/L-lactate dehydrogenase; SPTR: Malate/L-lactate dehydrogenase; PFAM: Malate/L-lactate dehydrogenase; Belongs to the LDH2/MDH2 oxidoreductase family. (349 aa)    
Predicted Functional Partners:
Toce_1898
Glyoxylate reductase; COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006140:IPR006139; KEGG: tpd:Teth39_2066 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; PRIAM: Glyoxylate reductase; SPTR: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain.
    
 0.738
Toce_1897
COGs: COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; InterPro IPR000887; KEGG: tit:Thit_0170 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; SPTR: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; TIGRFAM: Entner-Doudoroff aldolase.
       0.686
Toce_1900
PTS system sorbose subfamily IIB component; COGs: COG3444 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IIB; InterPro IPR004720; KEGG: tpd:Teth39_2067 PTS system sorbose subfamily IIB component; PFAM: PTS system sorbose subfamily IIB component; SPTR: PTS system sorbose subfamily IIB component; PFAM: PTS system sorbose subfamily IIB component.
       0.678
Toce_1901
COGs: COG2893 Phosphotransferase system mannose/fructose-specific component IIA; InterPro IPR004701; KEGG: tit:Thit_0165 PTS system fructose subfamily IIA component; PFAM: PTS system fructose subfamily IIA component; SPTR: PTS system fructose subfamily IIA component; PFAM: PTS system fructose IIA component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IIA component.
       0.635
Toce_1896
COGs: COG1023 6-phosphogluconate dehydrogenase; InterPro IPR006183:IPR004849:IPR006115:IPR006114; KEGG: cbk:CLL_A1312 6-phosphogluconate dehydrogenase-like protein; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; 6-phosphogluconate dehydrogenase domain protein; SPTR: 6-phosphogluconate dehydrogenase, decarboxylating; TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; 6-phosphogluconate dehydrogenase, C-terminal domain; TIGRFAM: 6-phosphogluconate dehydrogenase (decarboxylating); 6-phosphogluconate dehydrogenase, [...]
       0.476
Toce_1826
Fumarase alpha subunit; COGs: COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I N-terminal domain; InterPro IPR004646; KEGG: chy:CHY_0061 fumarate hydratase; PFAM: Fe-S type hydro-lyase tartrate/fumarate alpha region; PRIAM: Fumarate hydratase; SPTR: Fumarase alpha subunit; TIGRFAM: hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fumarate hydratase (Fumerase); TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha region.
     
 0.433
Toce_2204
InterPro IPR004995; KEGG: tit:Thit_2223 GerA spore germination protein; PFAM: GerA spore germination protein; SPTR: GerA spore germination protein; PFAM: Bacillus/Clostridium GerA spore germination protein.
   
    0.416
Toce_1902
PTS system IID component, Man family (TC 4.A.6); COGs: COG3716 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IID; InterPro IPR004704; KEGG: tpd:Teth39_2068 PTS system mannose/fructose/sorbose family IID component; PFAM: PTS system mannose/fructose/sorbose family IID component; SPTR: PTS system mannose/fructose/sorbose family IID component; PFAM: PTS system mannose/fructose/sorbose family IID component.
       0.415
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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