| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Toce_0521 | Toce_1913 | Toce_0521 | Toce_1913 | Transcriptional regulator/antitoxin, MazE; COGs: COG2336 Growth regulator; InterPro IPR007159; KEGG: gyc:GYMC61_2489 transcriptional regulator/antitoxin, MazE; PFAM: SpoVT/AbrB domain protein; SPTR: Suppressor of ppGpp-regulated growth inhibitor (ChpA/MazF); PFAM: SpoVT / AbrB like domain. | Transcriptional modulator of MazE/toxin, MazF; Toxic component of a type II toxin-antitoxin (TA) system. | 0.865 |
| Toce_1911 | Toce_1912 | Toce_1911 | Toce_1912 | Peptidase C26; COGs: COG2071 glutamine amidotransferase; InterPro IPR011697:IPR017926; KEGG: peptidase C26; PFAM: peptidase C26; SPTR: Peptidase C26; PFAM: Peptidase C26. | Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR003607:IPR006675:IPR006674; KEGG: mta:Moth_2495 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG. | 0.773 |
| Toce_1911 | Toce_1913 | Toce_1911 | Toce_1913 | Peptidase C26; COGs: COG2071 glutamine amidotransferase; InterPro IPR011697:IPR017926; KEGG: peptidase C26; PFAM: peptidase C26; SPTR: Peptidase C26; PFAM: Peptidase C26. | Transcriptional modulator of MazE/toxin, MazF; Toxic component of a type II toxin-antitoxin (TA) system. | 0.604 |
| Toce_1911 | Toce_1914 | Toce_1911 | Toce_1914 | Peptidase C26; COGs: COG2071 glutamine amidotransferase; InterPro IPR011697:IPR017926; KEGG: peptidase C26; PFAM: peptidase C26; SPTR: Peptidase C26; PFAM: Peptidase C26. | KEGG: aoe:Clos_2274 CopG family transcriptional regulator; SPTR: Putative transcriptional regulator, CopG family. | 0.604 |
| Toce_1911 | Toce_1915 | Toce_1911 | Toce_1915 | Peptidase C26; COGs: COG2071 glutamine amidotransferase; InterPro IPR011697:IPR017926; KEGG: peptidase C26; PFAM: peptidase C26; SPTR: Peptidase C26; PFAM: Peptidase C26. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.447 |
| Toce_1911 | acpS | Toce_1911 | Toce_1917 | Peptidase C26; COGs: COG2071 glutamine amidotransferase; InterPro IPR011697:IPR017926; KEGG: peptidase C26; PFAM: peptidase C26; SPTR: Peptidase C26; PFAM: Peptidase C26. | Holo-acyl-carrier-protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | 0.461 |
| Toce_1911 | nnrD | Toce_1911 | Toce_1916 | Peptidase C26; COGs: COG2071 glutamine amidotransferase; InterPro IPR011697:IPR017926; KEGG: peptidase C26; PFAM: peptidase C26; SPTR: Peptidase C26; PFAM: Peptidase C26. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.615 |
| Toce_1912 | Toce_1911 | Toce_1912 | Toce_1911 | Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR003607:IPR006675:IPR006674; KEGG: mta:Moth_2495 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG. | Peptidase C26; COGs: COG2071 glutamine amidotransferase; InterPro IPR011697:IPR017926; KEGG: peptidase C26; PFAM: peptidase C26; SPTR: Peptidase C26; PFAM: Peptidase C26. | 0.773 |
| Toce_1912 | Toce_1913 | Toce_1912 | Toce_1913 | Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR003607:IPR006675:IPR006674; KEGG: mta:Moth_2495 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG. | Transcriptional modulator of MazE/toxin, MazF; Toxic component of a type II toxin-antitoxin (TA) system. | 0.511 |
| Toce_1912 | Toce_1914 | Toce_1912 | Toce_1914 | Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR003607:IPR006675:IPR006674; KEGG: mta:Moth_2495 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG. | KEGG: aoe:Clos_2274 CopG family transcriptional regulator; SPTR: Putative transcriptional regulator, CopG family. | 0.511 |
| Toce_1912 | Toce_1915 | Toce_1912 | Toce_1915 | Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR003607:IPR006675:IPR006674; KEGG: mta:Moth_2495 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.405 |
| Toce_1912 | acpS | Toce_1912 | Toce_1917 | Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR003607:IPR006675:IPR006674; KEGG: mta:Moth_2495 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG. | Holo-acyl-carrier-protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | 0.405 |
| Toce_1912 | nnrD | Toce_1912 | Toce_1916 | Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR003607:IPR006675:IPR006674; KEGG: mta:Moth_2495 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.405 |
| Toce_1913 | Toce_0521 | Toce_1913 | Toce_0521 | Transcriptional modulator of MazE/toxin, MazF; Toxic component of a type II toxin-antitoxin (TA) system. | Transcriptional regulator/antitoxin, MazE; COGs: COG2336 Growth regulator; InterPro IPR007159; KEGG: gyc:GYMC61_2489 transcriptional regulator/antitoxin, MazE; PFAM: SpoVT/AbrB domain protein; SPTR: Suppressor of ppGpp-regulated growth inhibitor (ChpA/MazF); PFAM: SpoVT / AbrB like domain. | 0.865 |
| Toce_1913 | Toce_1911 | Toce_1913 | Toce_1911 | Transcriptional modulator of MazE/toxin, MazF; Toxic component of a type II toxin-antitoxin (TA) system. | Peptidase C26; COGs: COG2071 glutamine amidotransferase; InterPro IPR011697:IPR017926; KEGG: peptidase C26; PFAM: peptidase C26; SPTR: Peptidase C26; PFAM: Peptidase C26. | 0.604 |
| Toce_1913 | Toce_1912 | Toce_1913 | Toce_1912 | Transcriptional modulator of MazE/toxin, MazF; Toxic component of a type II toxin-antitoxin (TA) system. | Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR003607:IPR006675:IPR006674; KEGG: mta:Moth_2495 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG. | 0.511 |
| Toce_1913 | Toce_1914 | Toce_1913 | Toce_1914 | Transcriptional modulator of MazE/toxin, MazF; Toxic component of a type II toxin-antitoxin (TA) system. | KEGG: aoe:Clos_2274 CopG family transcriptional regulator; SPTR: Putative transcriptional regulator, CopG family. | 0.988 |
| Toce_1913 | Toce_1915 | Toce_1913 | Toce_1915 | Transcriptional modulator of MazE/toxin, MazF; Toxic component of a type II toxin-antitoxin (TA) system. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.630 |
| Toce_1913 | Toce_1961 | Toce_1913 | Toce_1961 | Transcriptional modulator of MazE/toxin, MazF; Toxic component of a type II toxin-antitoxin (TA) system. | COGs: COG1733 transcriptional regulator protein; InterPro IPR002577; KEGG: cbe:Cbei_3315 HxlR family transcriptional regulator; PFAM: helix-turn-helix HxlR type; SPTR: Transcriptional regulator, HxlR family; PFAM: HxlR-like helix-turn-helix. | 0.535 |
| Toce_1913 | Toce_2126 | Toce_1913 | Toce_2126 | Transcriptional modulator of MazE/toxin, MazF; Toxic component of a type II toxin-antitoxin (TA) system. | COGs: COG4463 Transcriptional repressor of class III stress genes; InterPro IPR008463; KEGG: chy:CHY_2351 transcriptional regulator CtsR; PFAM: Firmicute transcriptional repressor of class III stress genes; SPTR: Transcriptional regulator CtsR; PFAM: Firmicute transcriptional repressor of class III stress genes (CtsR); Belongs to the CtsR family. | 0.491 |