Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Toce_1914KEGG: aoe:Clos_2274 CopG family transcriptional regulator; SPTR: Putative transcriptional regulator, CopG family. (91 aa)    
Predicted Functional Partners:
Toce_1913
Transcriptional modulator of MazE/toxin, MazF; Toxic component of a type II toxin-antitoxin (TA) system.
  
 
 0.988
Toce_0520
Transcriptional modulator of MazE/toxin, MazF; COGs: COG2337 Growth inhibitor; InterPro IPR003477; KEGG: gka:GK1648 ppGpp-regulated growth inhibitor (ChpA/MazF); PFAM: PemK family protein; SPTR: PpGpp-regulated growth inhibitor (ChpA/MazF); manually curated; PFAM: PemK-like protein.
  
 
 0.861
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
       0.737
acpS
Holo-acyl-carrier-protein synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
       0.670
Toce_1915
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
       0.629
Toce_1318
InterPro IPR014194; KEGG: dae:Dtox_2607 stage III sporulation protein AE; PFAM: Sporulation stage III protein AE; SPTR: Stage III sporulation protein AE; TIGRFAM: stage III sporulation protein AE; PFAM: Stage III sporulation protein AE (spore_III_AE); TIGRFAM: stage III sporulation protein AE.
  
     0.622
Toce_1911
Peptidase C26; COGs: COG2071 glutamine amidotransferase; InterPro IPR011697:IPR017926; KEGG: peptidase C26; PFAM: peptidase C26; SPTR: Peptidase C26; PFAM: Peptidase C26.
       0.604
Toce_1411
Sporulation protein YtxC; InterPro IPR014199; KEGG: dae:Dtox_2403 sporulation protein YtxC; PFAM: Sporulation protein YtxC; SPTR: Putative uncharacterized protein; PFAM: YtxC-like family; TIGRFAM: putative sporulation protein YtxC.
  
     0.581
Toce_1051
Thioesterase superfamily protein; InterPro IPR001034:IPR006683:IPR017275; KEGG: tit:Thit_1285 protein for fatty acid biosynthesis transcriptional regulation; PFAM: thioesterase superfamily protein; regulatory protein DeoR; SPTR: Protein for fatty acid biosynthesis transcriptional regulation; manually curated; PFAM: Thioesterase superfamily; DeoR-like helix-turn-helix domain.
  
    0.575
Toce_1272
Stage II sporulation protein M; InterPro IPR014196:IPR002798; KEGG: aoe:Clos_1594 sporulation stage II protein M; PFAM: protein of unknown function DUF95 transmembrane; SPTR: Sporulation stage II protein M; TIGRFAM: stage II sporulation protein M; PFAM: Integral membrane protein DUF95; TIGRFAM: stage II sporulation protein M.
  
    0.562
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.