STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Toce_1930Type II secretion system protein E (GspE); COGs: COG2804 Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway ATPase PilB; InterPro IPR003593:IPR001482:IPR007831; KEGG: mta:Moth_1554 type II secretion system protein E; PFAM: type II secretion system protein E; General secretory system II protein E domain protein; SMART: AAA ATPase; SPTR: Type II secretion system protein E; PFAM: Type II/IV secretion system protein; GSPII_E N-terminal domain; TIGRFAM: type IV-A pilus assembly ATPase PilB; pilus retraction protein PilT; general secretory pathway protein E. (565 aa)    
Predicted Functional Partners:
Toce_1928
Type II secretion system F domain protein; COGs: COG1459 Type II secretory pathway component PulF; InterPro IPR001992:IPR003004:IPR018076; KEGG: mta:Moth_1552 type II secretion system protein; PFAM: Type II secretion system F domain; SPTR: Type II secretion system protein; PFAM: Bacterial type II secretion system protein F domain.
 
 0.976
Toce_1335
Type II secretion system F domain protein; COGs: COG1459 Type II secretory pathway component PulF; InterPro IPR018076:IPR003004; KEGG: tte:TTE1264 general secretory pathway protein F; PFAM: Type II secretion system F domain; SPTR: General secretory pathway protein F; PFAM: Bacterial type II secretion system protein F domain.
 
 
 0.960
Toce_1927
N-terminal methylation; COGs: COG2165 Type II secretory pathway pseudopilin PulG; InterPro IPR001120:IPR000983:IPR012902; KEGG: mta:Moth_1551 N-terminal methylation; SPTR: N-terminal methylation; PFAM: Prokaryotic N-terminal methylation motif; Bacterial type II secretion system protein G; TIGRFAM: general secretion pathway protein G; prepilin-type N-terminal cleavage/methylation domain.
 
 
 0.939
Toce_1926
Type 4 prepilin peptidase 1; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
 
 0.902
Toce_1929
Twitching motility protein; COGs: COG2805 Tfp pilus assembly protein pilus retraction ATPase PilT; InterPro IPR003593:IPR001482:IPR006321; KEGG: mta:Moth_1553 twitching motility protein; PFAM: type II secretion system protein E; SMART: AAA ATPase; SPTR: Twitching motility protein; TIGRFAM: twitching motility protein; PFAM: Type II/IV secretion system protein; TIGRFAM: pilus retraction protein PilT.
 
  
0.829
Toce_1922
COGs: COG4972 Tfp pilus assembly protein ATPase PilM; InterPro IPR005883; KEGG: mta:Moth_1545 pilus-associated protein PilM; SPTR: Pilus-associated protein pilM; TIGRFAM: type IV pilus assembly protein PilM; PFAM: Competence protein A; TIGRFAM: type IV pilus assembly protein PilM.
 
 
 0.821
Toce_1333
InterPro IPR012902; KEGG: dae:Dtox_2705 hypothetical protein; SPTR: N-terminal methylation protein; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain.
  
 
 0.790
Toce_1329
COGs: COG4972 Tfp pilus assembly protein ATPase PilM; InterPro IPR005883:IPR003494; KEGG: mxa:MXAN_5776 type IV pilus biogenesis protein PilM; PFAM: cell division protein FtsA; SPTR: Type IV pilus biogenesis protein PilM; TIGRFAM: type IV pilus assembly protein PilM; PFAM: Competence protein A; Cell division protein FtsA; TIGRFAM: type IV pilus assembly protein PilM.
 
 
 0.766
Toce_0773
Competence protein ComEA helix-hairpin-helix repeat protein; COGs: COG1555 DNA uptake protein and related DNA-binding protein; InterPro IPR003583:IPR004509:IPR019554:IPR000445; KEGG: mta:Moth_0570 competence protein ComEA helix-hairpin-helix region; PFAM: Soluble ligand binding domain; helix-hairpin-helix motif; SMART: Helix-hairpin-helix DNA-binding class 1; SPTR: Competence protein ComEA helix-hairpin-helix region; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: SLBB domain; Helix-hairpin-helix motif; TIGRFAM: competence protein ComEA helix-hairpin-helix r [...]
  
  
 0.749
Toce_1334
Conserved hypothetical protein; InterPro IPR012902:IPR001120:IPR000983; KEGG: tit:Thit_1059 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Prokaryotic N-terminal methylation motif; Bacterial type II secretion system protein G; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain.
 
 
 0.746
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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