Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Toce_1938DNA polymerase beta domain protein region; InterPro IPR002934; KEGG: chy:CHY_1896 nucleotidyltransferase domain-containing protein; PFAM: DNA polymerase beta domain protein region; SPTR: Nucleotidyltransferase domain protein; PFAM: Nucleotidyltransferase domain. (141 aa)    
Predicted Functional Partners:
Toce_1939
Protein of unknown function DUF86; COGs: COG2445 conserved hypothetical protein; InterPro IPR008201; KEGG: ckr:CKR_1141 hypothetical protein; PFAM: protein of unknown function DUF86; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function DUF86.
 
     0.949
Toce_2162
Protein of unknown function DUF86; COGs: COG2445 conserved hypothetical protein; InterPro IPR008201; KEGG: ate:Athe_0224 protein of unknown function DUF86; PFAM: protein of unknown function DUF86; SPTR: Putative toxin-antitoxin system, antitoxin component; PFAM: Protein of unknown function DUF86.
 
     0.743
Toce_0525
InterPro IPR010149; KEGG: csc:Csac_0076 CRISPR-associated Csm2 family protein; PFAM: CRISPR-associated protein TM1810 domain protein; SPTR: CRISPR-associated protein, Csm2 family; TIGRFAM: CRISPR-associated protein, Csm2 family; PFAM: Protein of unknown function (DUF310); TIGRFAM: CRISPR-associated protein, Csm2 family.
  
     0.523
Toce_0543
HEPN domain protein; COGs: COG2250 conserved hypothetical protein related to C-terminal domain of eukaryotic chaperone SACSIN; InterPro IPR007842; KEGG: tye:THEYE_A1691 HEPN domain, putative; PFAM: HEPN domain protein; SMART: HEPN domain protein; SPTR: Hepn domain, putative; PFAM: HEPN domain.
 
     0.519
Toce_0528
CRISPR-associated RAMP protein, Csm5 family; COGs: COG1332 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily); InterPro IPR010173:IPR005537; KEGG: ate:Athe_2700 CRISPR-associated RAMP protein, Csm5 family; PFAM: protein of unknown function DUF324; SPTR: CRISPR-associated RAMP protein, Csm5 family; TIGRFAM: CRISPR-associated RAMP protein, Csm5 family; PFAM: RAMP superfamily; TIGRFAM: CRISPR-associated RAMP protein, Csm5 family.
  
     0.474
Toce_1493
Protein of unknown function DUF1284; COGs: COG3543 conserved hypothetical protein; InterPro IPR009702; KEGG: adg:Adeg_0990 protein of unknown function DUF1284; PFAM: protein of unknown function DUF1284; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1284).
  
     0.474
Toce_0524
CRISPR-associated protein, Csm1 family; COGs: COG1353 hydrolase of the HD superfamily (permuted catalytic motifs); InterPro IPR000160:IPR013408; KEGG: ate:Athe_2704 metal dependent phosphohydrolase; SPTR: Metal dependent phosphohydrolase; TIGRFAM: CRISPR-associated protein, Csm1 family; PFAM: HD domain; TIGRFAM: CRISPR-associated protein, Csm1 family.
  
   
 0.419
Toce_0579
Protein of unknown function DUF820; COGs: COG4636 conserved hypothetical protein; InterPro IPR008538; KEGG: ate:Athe_0024 protein of unknown function DUF820; PFAM: protein of unknown function DUF820; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF820).
  
     0.419
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.