Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Toce_1961COGs: COG1733 transcriptional regulator protein; InterPro IPR002577; KEGG: cbe:Cbei_3315 HxlR family transcriptional regulator; PFAM: helix-turn-helix HxlR type; SPTR: Transcriptional regulator, HxlR family; PFAM: HxlR-like helix-turn-helix. (117 aa)    
Predicted Functional Partners:
Toce_0520
Transcriptional modulator of MazE/toxin, MazF; COGs: COG2337 Growth inhibitor; InterPro IPR003477; KEGG: gka:GK1648 ppGpp-regulated growth inhibitor (ChpA/MazF); PFAM: PemK family protein; SPTR: PpGpp-regulated growth inhibitor (ChpA/MazF); manually curated; PFAM: PemK-like protein.
   
    0.535
Toce_1913
Transcriptional modulator of MazE/toxin, MazF; Toxic component of a type II toxin-antitoxin (TA) system.
   
    0.535
Toce_1960
InterPro IPR000182; KEGG: pjd:Pjdr2_6089 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: Acetyltransferase; PFAM: Acetyltransferase (GNAT) family.
       0.525
Toce_1935
COGs: COG5015 conserved hypothetical protein; InterPro IPR011576; KEGG: drm:Dred_0307 pyridoxamine 5'-phosphate oxidase-related, FMN-binding; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; SPTR: Pyridoxamine 5'-phosphate oxidase-related, FMN-binding; PFAM: Pyridoxamine 5'-phosphate oxidase.
 
     0.408
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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