Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dacAProtein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (273 aa)    
Predicted Functional Partners:
Toce_1969
YbbR family protein; COGs: COG4856 conserved hypothetical protein; InterPro IPR012505; KEGG: tpd:Teth39_0458 YbbR family protein; PFAM: YbbR family protein; SPTR: YbbR family protein; PFAM: YbbR-like protein.
 
  
 0.976
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
   
 
 0.952
Toce_0825
COGs: COG1109 Phosphomannomutase; InterProIPR016066:IPR005841:IPR005844:IPR005845:IPR 005846:IPR005843; KEGG: tte:TTE0731 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: Phosphomannomutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, C [...]
   
 
 0.874
Toce_1971
KEGG: nth:Nther_2043 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.581
mutS2
MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
 
     0.576
Toce_2253
COGs: COG3887 signaling protein consisting of a modified GGDEF domain and a DHH domain; InterPro IPR000160:IPR001667:IPR003156; KEGG: aoe:Clos_2799 phosphoesterase domain-containing protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase RecJ domain protein; PFAM: DHH family; DHHA1 domain.
  
   
 0.575
Toce_1235
Phosphoesterase RecJ domain protein; COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667:IPR003156; KEGG: cth:Cthe_0989 phosphoesterase, RecJ-like protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase, RecJ-like protein; PFAM: DHH family; DHHA1 domain.
 
   
 0.569
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
     
 0.518
Toce_0738
Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
  
  
 0.511
Toce_1029
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
     
 0.502
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (34%) [HD]