| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Toce_0738 | dacA | Toce_0738 | Toce_1970 | Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Protein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.511 |
| Toce_0825 | dacA | Toce_0825 | Toce_1970 | COGs: COG1109 Phosphomannomutase; InterProIPR016066:IPR005841:IPR005844:IPR005845:IPR 005846:IPR005843; KEGG: tte:TTE0731 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: Phosphomannomutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, C [...] | Protein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.874 |
| Toce_1029 | Toce_1235 | Toce_1029 | Toce_1235 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Phosphoesterase RecJ domain protein; COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667:IPR003156; KEGG: cth:Cthe_0989 phosphoesterase, RecJ-like protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase, RecJ-like protein; PFAM: DHH family; DHHA1 domain. | 0.447 |
| Toce_1029 | dacA | Toce_1029 | Toce_1970 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Protein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.502 |
| Toce_1029 | dapA | Toce_1029 | Toce_0017 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). | 0.434 |
| Toce_1029 | mutS2 | Toce_1029 | Toce_1392 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. | 0.401 |
| Toce_1235 | Toce_1029 | Toce_1235 | Toce_1029 | Phosphoesterase RecJ domain protein; COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667:IPR003156; KEGG: cth:Cthe_0989 phosphoesterase, RecJ-like protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase, RecJ-like protein; PFAM: DHH family; DHHA1 domain. | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.447 |
| Toce_1235 | Toce_2253 | Toce_1235 | Toce_2253 | Phosphoesterase RecJ domain protein; COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667:IPR003156; KEGG: cth:Cthe_0989 phosphoesterase, RecJ-like protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase, RecJ-like protein; PFAM: DHH family; DHHA1 domain. | COGs: COG3887 signaling protein consisting of a modified GGDEF domain and a DHH domain; InterPro IPR000160:IPR001667:IPR003156; KEGG: aoe:Clos_2799 phosphoesterase domain-containing protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase RecJ domain protein; PFAM: DHH family; DHHA1 domain. | 0.451 |
| Toce_1235 | dacA | Toce_1235 | Toce_1970 | Phosphoesterase RecJ domain protein; COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667:IPR003156; KEGG: cth:Cthe_0989 phosphoesterase, RecJ-like protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase, RecJ-like protein; PFAM: DHH family; DHHA1 domain. | Protein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.569 |
| Toce_1969 | Toce_1971 | Toce_1969 | Toce_1971 | YbbR family protein; COGs: COG4856 conserved hypothetical protein; InterPro IPR012505; KEGG: tpd:Teth39_0458 YbbR family protein; PFAM: YbbR family protein; SPTR: YbbR family protein; PFAM: YbbR-like protein. | KEGG: nth:Nther_2043 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.581 |
| Toce_1969 | Toce_2253 | Toce_1969 | Toce_2253 | YbbR family protein; COGs: COG4856 conserved hypothetical protein; InterPro IPR012505; KEGG: tpd:Teth39_0458 YbbR family protein; PFAM: YbbR family protein; SPTR: YbbR family protein; PFAM: YbbR-like protein. | COGs: COG3887 signaling protein consisting of a modified GGDEF domain and a DHH domain; InterPro IPR000160:IPR001667:IPR003156; KEGG: aoe:Clos_2799 phosphoesterase domain-containing protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase RecJ domain protein; PFAM: DHH family; DHHA1 domain. | 0.436 |
| Toce_1969 | dacA | Toce_1969 | Toce_1970 | YbbR family protein; COGs: COG4856 conserved hypothetical protein; InterPro IPR012505; KEGG: tpd:Teth39_0458 YbbR family protein; PFAM: YbbR family protein; SPTR: YbbR family protein; PFAM: YbbR-like protein. | Protein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.976 |
| Toce_1969 | glmM | Toce_1969 | Toce_1968 | YbbR family protein; COGs: COG4856 conserved hypothetical protein; InterPro IPR012505; KEGG: tpd:Teth39_0458 YbbR family protein; PFAM: YbbR family protein; SPTR: YbbR family protein; PFAM: YbbR-like protein. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.730 |
| Toce_1971 | Toce_1969 | Toce_1971 | Toce_1969 | KEGG: nth:Nther_2043 hypothetical protein; SPTR: Putative uncharacterized protein. | YbbR family protein; COGs: COG4856 conserved hypothetical protein; InterPro IPR012505; KEGG: tpd:Teth39_0458 YbbR family protein; PFAM: YbbR family protein; SPTR: YbbR family protein; PFAM: YbbR-like protein. | 0.581 |
| Toce_1971 | dacA | Toce_1971 | Toce_1970 | KEGG: nth:Nther_2043 hypothetical protein; SPTR: Putative uncharacterized protein. | Protein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.581 |
| Toce_1971 | glmM | Toce_1971 | Toce_1968 | KEGG: nth:Nther_2043 hypothetical protein; SPTR: Putative uncharacterized protein. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.483 |
| Toce_2253 | Toce_1235 | Toce_2253 | Toce_1235 | COGs: COG3887 signaling protein consisting of a modified GGDEF domain and a DHH domain; InterPro IPR000160:IPR001667:IPR003156; KEGG: aoe:Clos_2799 phosphoesterase domain-containing protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase RecJ domain protein; PFAM: DHH family; DHHA1 domain. | Phosphoesterase RecJ domain protein; COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667:IPR003156; KEGG: cth:Cthe_0989 phosphoesterase, RecJ-like protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase, RecJ-like protein; PFAM: DHH family; DHHA1 domain. | 0.451 |
| Toce_2253 | Toce_1969 | Toce_2253 | Toce_1969 | COGs: COG3887 signaling protein consisting of a modified GGDEF domain and a DHH domain; InterPro IPR000160:IPR001667:IPR003156; KEGG: aoe:Clos_2799 phosphoesterase domain-containing protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase RecJ domain protein; PFAM: DHH family; DHHA1 domain. | YbbR family protein; COGs: COG4856 conserved hypothetical protein; InterPro IPR012505; KEGG: tpd:Teth39_0458 YbbR family protein; PFAM: YbbR family protein; SPTR: YbbR family protein; PFAM: YbbR-like protein. | 0.436 |
| Toce_2253 | dacA | Toce_2253 | Toce_1970 | COGs: COG3887 signaling protein consisting of a modified GGDEF domain and a DHH domain; InterPro IPR000160:IPR001667:IPR003156; KEGG: aoe:Clos_2799 phosphoesterase domain-containing protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase RecJ domain protein; PFAM: DHH family; DHHA1 domain. | Protein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.575 |
| dacA | Toce_0738 | Toce_1970 | Toce_0738 | Protein of unknown function DUF147; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.511 |