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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Toce_1987tRNA (adenine-58-N(1)-) methyltransferase; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA. (255 aa)    
Predicted Functional Partners:
Toce_1816
PP-loop domain protein; COGs: COG0037 ATPase of the PP-loop superfamily protein implicated in cell cycle control; InterPro IPR011063:IPR012089; KEGG: ate:Athe_0195 PP-loop domain protein; PFAM: PP-loop domain protein; SPTR: PP-loop domain protein; PFAM: PP-loop family; TIGRFAM: conserved hypothetical protein TIGR00269; Belongs to the TtcA family.
 
  
 0.841
bpsA
Protein of unknown function DUF43; Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.
  
     0.716
mobA
Molybdenum cofactor guanylyltransferase; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
       0.714
Toce_1553
23S rRNA m(5)U-1939 methyltransferase; COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; InterPro IPR001566:IPR002792:IPR010280; KEGG: tpd:Teth39_0686 RNA methyltransferase; PFAM: (Uracil-5)-methyltransferase; deoxyribonuclease/rho motif-related TRAM; SPTR: RNA methyltransferase, TrmA family; TIGRFAM: RNA methyltransferase, TrmA family; PFAM: TRAM domain; tRNA (Uracil-5-)-methyltransferase; TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
   
  
 0.662
Toce_0479
tRNA pseudouridine synthase D TruD; COGs: COG0585 conserved hypothetical protein; InterPro IPR011760:IPR020119:IPR001656; KEGG: csc:Csac_1232 tRNA pseudouridine synthase D, TruD; PFAM: tRNA pseudouridine synthase D TruD; SPTR: tRNA pseudouridine synthase D, TruD; PFAM: tRNA pseudouridine synthase D (TruD); TIGRFAM: conserved hypothetical protein TIGR00094.
  
  
 0.544
Toce_1588
COGs: COG0438 Glycosyltransferase; InterProIPR001296:IPR013216:IPR001173:IPR019734:IPR 013026:IPR000276; KEGG: tnp:Tnap_0554 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; Methyltransferase type 11; glycosyl transferase group 1; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase family 2; PFAM: Methyltransferase domain; Glycosyl transferases group 1; Glycosyl transferase family 2.
 
    0.496
cysS
COGs: COG0215 Cysteinyl-tRNA synthetase; InterPro IPR015803:IPR002308:IPR015273; KEGG: tit:Thit_1996 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; PRIAM: Cysteine--tRNA ligase; SPTR: Cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
   0.495
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
   
  
 0.482
Toce_1989
Transposase IS4 family protein; COGs: COG3666 Transposase and inactivated derivatives; InterPro IPR002559; KEGG: tte:TTE2646 transposase; PFAM: transposase IS4 family protein; SPTR: Transposase; PFAM: Transposase DDE domain; Transposase domain (DUF772).
       0.462
rsmA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
  
  
 0.459
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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