node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Toce_0310 | Toce_0321 | Toce_0310 | Toce_0321 | precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR003722; KEGG: tit:Thit_0351 precorrin-8X methylmutase; PFAM: Precorrin-8X methylmutase CbiC/CobH; PRIAM: Precorrin-8X methylmutase; SPTR: Precorrin-8X methylmutase CbiC/CobH; PFAM: Precorrin-8X methylmutase. | COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR003043:IPR006366:IPR000878:IPR003754; KEGG: tex:Teth514_0319 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | 0.945 |
Toce_0310 | Toce_1422 | Toce_0310 | Toce_1422 | precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR003722; KEGG: tit:Thit_0351 precorrin-8X methylmutase; PFAM: Precorrin-8X methylmutase CbiC/CobH; PRIAM: Precorrin-8X methylmutase; SPTR: Precorrin-8X methylmutase CbiC/CobH; PFAM: Precorrin-8X methylmutase. | L-threonine-O-3-phosphate decarboxylase; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR005860:IPR004839:IPR004838; KEGG: cpe:CPE1040 threonine-phosphate decarboxylase; PFAM: aminotransferase class I and II; SPTR: Putative L-threonine-O-3-phosphate decarboxylase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: Aminotransferase class I and II; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; histidinol-phosphate aminotransferase. | 0.694 |
Toce_0310 | Toce_1423 | Toce_0310 | Toce_1423 | precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR003722; KEGG: tit:Thit_0351 precorrin-8X methylmutase; PFAM: Precorrin-8X methylmutase CbiC/CobH; PRIAM: Precorrin-8X methylmutase; SPTR: Precorrin-8X methylmutase CbiC/CobH; PFAM: Precorrin-8X methylmutase. | GHMP kinase; COGs: COG4542 Protein involved in propanediol utilization and related protein (includes coumermycin biosynthetic protein) possible kinase; InterPro IPR006204:IPR013750:IPR012363; KEGG: mta:Moth_1103 GHMP kinase; PFAM: GHMP kinase; GHMP kinase domain protein; SPTR: GHMP kinase; PFAM: GHMP kinases C terminal; GHMP kinases N terminal domain. | 0.696 |
Toce_0310 | Toce_2006 | Toce_0310 | Toce_2006 | precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR003722; KEGG: tit:Thit_0351 precorrin-8X methylmutase; PFAM: Precorrin-8X methylmutase CbiC/CobH; PRIAM: Precorrin-8X methylmutase; SPTR: Precorrin-8X methylmutase CbiC/CobH; PFAM: Precorrin-8X methylmutase. | KEGG: hmo:HM1_1579 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.440 |
Toce_0310 | cobD | Toce_0310 | Toce_1421 | precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR003722; KEGG: tit:Thit_0351 precorrin-8X methylmutase; PFAM: Precorrin-8X methylmutase CbiC/CobH; PRIAM: Precorrin-8X methylmutase; SPTR: Precorrin-8X methylmutase CbiC/CobH; PFAM: Precorrin-8X methylmutase. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.883 |
Toce_0310 | cobS | Toce_0310 | Toce_1420 | precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR003722; KEGG: tit:Thit_0351 precorrin-8X methylmutase; PFAM: Precorrin-8X methylmutase CbiC/CobH; PRIAM: Precorrin-8X methylmutase; SPTR: Precorrin-8X methylmutase CbiC/CobH; PFAM: Precorrin-8X methylmutase. | Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.745 |
Toce_0310 | hemL | Toce_0310 | Toce_0323 | precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR003722; KEGG: tit:Thit_0351 precorrin-8X methylmutase; PFAM: Precorrin-8X methylmutase CbiC/CobH; PRIAM: Precorrin-8X methylmutase; SPTR: Precorrin-8X methylmutase CbiC/CobH; PFAM: Precorrin-8X methylmutase. | Glutamate-1-semialdehyde-2,1-aminomutase; COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; InterPro IPR005814:IPR006367:IPR004639; KEGG: tex:Teth514_0321 glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; SPTR: Glutamate-1-semialdehyde-2,1-aminomutase; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; siroheme synthase; PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; siroheme synthase, N-terminal domain; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. | 0.922 |
Toce_0321 | Toce_0310 | Toce_0321 | Toce_0310 | COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR003043:IPR006366:IPR000878:IPR003754; KEGG: tex:Teth514_0319 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | precorrin-8X methylmutase; COGs: COG2082 Precorrin isomerase; InterPro IPR003722; KEGG: tit:Thit_0351 precorrin-8X methylmutase; PFAM: Precorrin-8X methylmutase CbiC/CobH; PRIAM: Precorrin-8X methylmutase; SPTR: Precorrin-8X methylmutase CbiC/CobH; PFAM: Precorrin-8X methylmutase. | 0.945 |
Toce_0321 | Toce_0791 | Toce_0321 | Toce_0791 | COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR003043:IPR006366:IPR000878:IPR003754; KEGG: tex:Teth514_0319 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | KEGG: amt:Amet_2095 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D). | 0.551 |
Toce_0321 | Toce_1422 | Toce_0321 | Toce_1422 | COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR003043:IPR006366:IPR000878:IPR003754; KEGG: tex:Teth514_0319 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | L-threonine-O-3-phosphate decarboxylase; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR005860:IPR004839:IPR004838; KEGG: cpe:CPE1040 threonine-phosphate decarboxylase; PFAM: aminotransferase class I and II; SPTR: Putative L-threonine-O-3-phosphate decarboxylase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: Aminotransferase class I and II; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; histidinol-phosphate aminotransferase. | 0.708 |
Toce_0321 | Toce_1423 | Toce_0321 | Toce_1423 | COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR003043:IPR006366:IPR000878:IPR003754; KEGG: tex:Teth514_0319 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | GHMP kinase; COGs: COG4542 Protein involved in propanediol utilization and related protein (includes coumermycin biosynthetic protein) possible kinase; InterPro IPR006204:IPR013750:IPR012363; KEGG: mta:Moth_1103 GHMP kinase; PFAM: GHMP kinase; GHMP kinase domain protein; SPTR: GHMP kinase; PFAM: GHMP kinases C terminal; GHMP kinases N terminal domain. | 0.513 |
Toce_0321 | Toce_2006 | Toce_0321 | Toce_2006 | COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR003043:IPR006366:IPR000878:IPR003754; KEGG: tex:Teth514_0319 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | KEGG: hmo:HM1_1579 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.454 |
Toce_0321 | cobD | Toce_0321 | Toce_1421 | COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR003043:IPR006366:IPR000878:IPR003754; KEGG: tex:Teth514_0319 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.775 |
Toce_0321 | cobS | Toce_0321 | Toce_1420 | COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR003043:IPR006366:IPR000878:IPR003754; KEGG: tex:Teth514_0319 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | Cobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.775 |
Toce_0321 | hemL | Toce_0321 | Toce_0323 | COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR003043:IPR006366:IPR000878:IPR003754; KEGG: tex:Teth514_0319 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | Glutamate-1-semialdehyde-2,1-aminomutase; COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; InterPro IPR005814:IPR006367:IPR004639; KEGG: tex:Teth514_0321 glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; SPTR: Glutamate-1-semialdehyde-2,1-aminomutase; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; siroheme synthase; PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; siroheme synthase, N-terminal domain; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. | 0.999 |
Toce_0788 | Toce_0791 | Toce_0788 | Toce_0791 | KEGG: dhd:Dhaf_2572 protein of unknown function DUF1638; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1638). | KEGG: amt:Amet_2095 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D). | 0.781 |
Toce_0788 | Toce_2006 | Toce_0788 | Toce_2006 | KEGG: dhd:Dhaf_2572 protein of unknown function DUF1638; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1638). | KEGG: hmo:HM1_1579 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.470 |
Toce_0791 | Toce_0321 | Toce_0791 | Toce_0321 | KEGG: amt:Amet_2095 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D). | COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR003043:IPR006366:IPR000878:IPR003754; KEGG: tex:Teth514_0319 uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | 0.551 |
Toce_0791 | Toce_0788 | Toce_0791 | Toce_0788 | KEGG: amt:Amet_2095 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D). | KEGG: dhd:Dhaf_2572 protein of unknown function DUF1638; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1638). | 0.781 |
Toce_0791 | Toce_2005 | Toce_0791 | Toce_2005 | KEGG: amt:Amet_2095 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D). | KEGG: chy:CHY_0775 hypothetical protein; SPTR: Putative membrane protein; PFAM: Protein of unknown function (DUF1393). | 0.482 |