| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Toce_0100 | Toce_0980 | Toce_0100 | Toce_0980 | Transcriptional regulator, AbrB family; InterPro IPR014213:IPR006339:IPR007159; KEGG: pth:PTH_0119 regulators of stationary/sporulation gene expression; PFAM: SpoVT/AbrB domain protein; SPTR: Regulators of stationary/sporulation gene expression; TIGRFAM: stage V sporulation protein T; transcriptional regulator, AbrB family; PFAM: SpoVT / AbrB like domain; TIGRFAM: looped-hinge helix DNA binding domain, AbrB family; stage V sporulation protein T. | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | 0.803 |
| Toce_0100 | Toce_1300 | Toce_0100 | Toce_1300 | Transcriptional regulator, AbrB family; InterPro IPR014213:IPR006339:IPR007159; KEGG: pth:PTH_0119 regulators of stationary/sporulation gene expression; PFAM: SpoVT/AbrB domain protein; SPTR: Regulators of stationary/sporulation gene expression; TIGRFAM: stage V sporulation protein T; transcriptional regulator, AbrB family; PFAM: SpoVT / AbrB like domain; TIGRFAM: looped-hinge helix DNA binding domain, AbrB family; stage V sporulation protein T. | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.835 |
| Toce_0100 | Toce_1315 | Toce_0100 | Toce_1315 | Transcriptional regulator, AbrB family; InterPro IPR014213:IPR006339:IPR007159; KEGG: pth:PTH_0119 regulators of stationary/sporulation gene expression; PFAM: SpoVT/AbrB domain protein; SPTR: Regulators of stationary/sporulation gene expression; TIGRFAM: stage V sporulation protein T; transcriptional regulator, AbrB family; PFAM: SpoVT / AbrB like domain; TIGRFAM: looped-hinge helix DNA binding domain, AbrB family; stage V sporulation protein T. | KEGG: tit:Thit_1084 hypothetical protein; SPTR: Stage III sporulation protein AH. | 0.797 |
| Toce_0100 | Toce_1318 | Toce_0100 | Toce_1318 | Transcriptional regulator, AbrB family; InterPro IPR014213:IPR006339:IPR007159; KEGG: pth:PTH_0119 regulators of stationary/sporulation gene expression; PFAM: SpoVT/AbrB domain protein; SPTR: Regulators of stationary/sporulation gene expression; TIGRFAM: stage V sporulation protein T; transcriptional regulator, AbrB family; PFAM: SpoVT / AbrB like domain; TIGRFAM: looped-hinge helix DNA binding domain, AbrB family; stage V sporulation protein T. | InterPro IPR014194; KEGG: dae:Dtox_2607 stage III sporulation protein AE; PFAM: Sporulation stage III protein AE; SPTR: Stage III sporulation protein AE; TIGRFAM: stage III sporulation protein AE; PFAM: Stage III sporulation protein AE (spore_III_AE); TIGRFAM: stage III sporulation protein AE. | 0.726 |
| Toce_0100 | Toce_1320 | Toce_0100 | Toce_1320 | Transcriptional regulator, AbrB family; InterPro IPR014213:IPR006339:IPR007159; KEGG: pth:PTH_0119 regulators of stationary/sporulation gene expression; PFAM: SpoVT/AbrB domain protein; SPTR: Regulators of stationary/sporulation gene expression; TIGRFAM: stage V sporulation protein T; transcriptional regulator, AbrB family; PFAM: SpoVT / AbrB like domain; TIGRFAM: looped-hinge helix DNA binding domain, AbrB family; stage V sporulation protein T. | Stage III sporulation protein AC; InterPro IPR009570:IPR005829; KEGG: amt:Amet_2494 stage III sporulation AC family protein; SPTR: Stage III sporulation AC family protein; TIGRFAM: stage III sporulation protein AC; PFAM: Stage III sporulation protein AC/AD protein family; TIGRFAM: stage III sporulation protein AC. | 0.764 |
| Toce_0100 | Toce_1322 | Toce_0100 | Toce_1322 | Transcriptional regulator, AbrB family; InterPro IPR014213:IPR006339:IPR007159; KEGG: pth:PTH_0119 regulators of stationary/sporulation gene expression; PFAM: SpoVT/AbrB domain protein; SPTR: Regulators of stationary/sporulation gene expression; TIGRFAM: stage V sporulation protein T; transcriptional regulator, AbrB family; PFAM: SpoVT / AbrB like domain; TIGRFAM: looped-hinge helix DNA binding domain, AbrB family; stage V sporulation protein T. | Stage III sporulation protein AA; COGs: COG3854 conserved hypothetical protein; InterPro IPR014217:IPR003593; KEGG: tpd:Teth39_1088 AAA ATPase; SMART: AAA ATPase; SPTR: AAA ATPase; TIGRFAM: stage III sporulation protein AA; TIGRFAM: stage III sporulation protein AA. | 0.834 |
| Toce_0100 | Toce_2013 | Toce_0100 | Toce_2013 | Transcriptional regulator, AbrB family; InterPro IPR014213:IPR006339:IPR007159; KEGG: pth:PTH_0119 regulators of stationary/sporulation gene expression; PFAM: SpoVT/AbrB domain protein; SPTR: Regulators of stationary/sporulation gene expression; TIGRFAM: stage V sporulation protein T; transcriptional regulator, AbrB family; PFAM: SpoVT / AbrB like domain; TIGRFAM: looped-hinge helix DNA binding domain, AbrB family; stage V sporulation protein T. | InterPro IPR018356:IPR014208; KEGG: hor:Hore_17740 sporulation stage III transcriptional regulator SpoIIID; SPTR: Sporulation stage III transcriptional regulator SpoIIID; TIGRFAM: sporulation transcriptional regulator SpoIIID; PFAM: Stage III sporulation protein D; TIGRFAM: sporulation transcriptional regulator SpoIIID. | 0.883 |
| Toce_0100 | Toce_2099 | Toce_0100 | Toce_2099 | Transcriptional regulator, AbrB family; InterPro IPR014213:IPR006339:IPR007159; KEGG: pth:PTH_0119 regulators of stationary/sporulation gene expression; PFAM: SpoVT/AbrB domain protein; SPTR: Regulators of stationary/sporulation gene expression; TIGRFAM: stage V sporulation protein T; transcriptional regulator, AbrB family; PFAM: SpoVT / AbrB like domain; TIGRFAM: looped-hinge helix DNA binding domain, AbrB family; stage V sporulation protein T. | Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR001932:IPR006162:IPR014221:IPR010822; KEGG: cce:Ccel_2986 stage II sporulation protein E, protein serine/threonine phosphatase; PFAM: Stage II sporulation E family protein; PRIAM: Phosphoprotein phosphatase; SMART: protein phosphatase 2C domain protein; SPTR: Stage II sporulation protein E, protein serine/threonine phosphatase; TIGRFAM: stage II sporulation protein E; manually curated; PFAM: Stage II sporulation protein E (SpoIIE); TIGRFAM: stage II sporulation protein E. | 0.827 |
| Toce_0100 | Toce_2201 | Toce_0100 | Toce_2201 | Transcriptional regulator, AbrB family; InterPro IPR014213:IPR006339:IPR007159; KEGG: pth:PTH_0119 regulators of stationary/sporulation gene expression; PFAM: SpoVT/AbrB domain protein; SPTR: Regulators of stationary/sporulation gene expression; TIGRFAM: stage V sporulation protein T; transcriptional regulator, AbrB family; PFAM: SpoVT / AbrB like domain; TIGRFAM: looped-hinge helix DNA binding domain, AbrB family; stage V sporulation protein T. | Stage II sporulation protein R; InterPro IPR014202; KEGG: tex:Teth514_0606 hypothetical protein; PFAM: Sporulation stage II protein R; SPTR: Stage II sporulation protein R; TIGRFAM: stage II sporulation protein R; PFAM: Stage II sporulation protein R (spore_II_R); TIGRFAM: stage II sporulation protein R. | 0.846 |
| Toce_0100 | spoIIAB | Toce_0100 | Toce_1268 | Transcriptional regulator, AbrB family; InterPro IPR014213:IPR006339:IPR007159; KEGG: pth:PTH_0119 regulators of stationary/sporulation gene expression; PFAM: SpoVT/AbrB domain protein; SPTR: Regulators of stationary/sporulation gene expression; TIGRFAM: stage V sporulation protein T; transcriptional regulator, AbrB family; PFAM: SpoVT / AbrB like domain; TIGRFAM: looped-hinge helix DNA binding domain, AbrB family; stage V sporulation protein T. | Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.870 |
| Toce_0980 | Toce_0100 | Toce_0980 | Toce_0100 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | Transcriptional regulator, AbrB family; InterPro IPR014213:IPR006339:IPR007159; KEGG: pth:PTH_0119 regulators of stationary/sporulation gene expression; PFAM: SpoVT/AbrB domain protein; SPTR: Regulators of stationary/sporulation gene expression; TIGRFAM: stage V sporulation protein T; transcriptional regulator, AbrB family; PFAM: SpoVT / AbrB like domain; TIGRFAM: looped-hinge helix DNA binding domain, AbrB family; stage V sporulation protein T. | 0.803 |
| Toce_0980 | Toce_1300 | Toce_0980 | Toce_1300 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.868 |
| Toce_0980 | Toce_1315 | Toce_0980 | Toce_1315 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | KEGG: tit:Thit_1084 hypothetical protein; SPTR: Stage III sporulation protein AH. | 0.870 |
| Toce_0980 | Toce_1318 | Toce_0980 | Toce_1318 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | InterPro IPR014194; KEGG: dae:Dtox_2607 stage III sporulation protein AE; PFAM: Sporulation stage III protein AE; SPTR: Stage III sporulation protein AE; TIGRFAM: stage III sporulation protein AE; PFAM: Stage III sporulation protein AE (spore_III_AE); TIGRFAM: stage III sporulation protein AE. | 0.793 |
| Toce_0980 | Toce_1320 | Toce_0980 | Toce_1320 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | Stage III sporulation protein AC; InterPro IPR009570:IPR005829; KEGG: amt:Amet_2494 stage III sporulation AC family protein; SPTR: Stage III sporulation AC family protein; TIGRFAM: stage III sporulation protein AC; PFAM: Stage III sporulation protein AC/AD protein family; TIGRFAM: stage III sporulation protein AC. | 0.863 |
| Toce_0980 | Toce_1322 | Toce_0980 | Toce_1322 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | Stage III sporulation protein AA; COGs: COG3854 conserved hypothetical protein; InterPro IPR014217:IPR003593; KEGG: tpd:Teth39_1088 AAA ATPase; SMART: AAA ATPase; SPTR: AAA ATPase; TIGRFAM: stage III sporulation protein AA; TIGRFAM: stage III sporulation protein AA. | 0.886 |
| Toce_0980 | Toce_2013 | Toce_0980 | Toce_2013 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | InterPro IPR018356:IPR014208; KEGG: hor:Hore_17740 sporulation stage III transcriptional regulator SpoIIID; SPTR: Sporulation stage III transcriptional regulator SpoIIID; TIGRFAM: sporulation transcriptional regulator SpoIIID; PFAM: Stage III sporulation protein D; TIGRFAM: sporulation transcriptional regulator SpoIIID. | 0.894 |
| Toce_0980 | Toce_2099 | Toce_0980 | Toce_2099 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR001932:IPR006162:IPR014221:IPR010822; KEGG: cce:Ccel_2986 stage II sporulation protein E, protein serine/threonine phosphatase; PFAM: Stage II sporulation E family protein; PRIAM: Phosphoprotein phosphatase; SMART: protein phosphatase 2C domain protein; SPTR: Stage II sporulation protein E, protein serine/threonine phosphatase; TIGRFAM: stage II sporulation protein E; manually curated; PFAM: Stage II sporulation protein E (SpoIIE); TIGRFAM: stage II sporulation protein E. | 0.836 |
| Toce_0980 | Toce_2201 | Toce_0980 | Toce_2201 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | Stage II sporulation protein R; InterPro IPR014202; KEGG: tex:Teth514_0606 hypothetical protein; PFAM: Sporulation stage II protein R; SPTR: Stage II sporulation protein R; TIGRFAM: stage II sporulation protein R; PFAM: Stage II sporulation protein R (spore_II_R); TIGRFAM: stage II sporulation protein R. | 0.848 |
| Toce_0980 | spoIIAB | Toce_0980 | Toce_1268 | Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat. | Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.854 |