STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Toce_2029ATP-NAD/AcoX kinase; COGs: COG3199 conserved hypothetical protein; InterPro IPR011391:IPR002504; KEGG: tpd:Teth39_0792 ATP-NAD/AcoX kinase; PFAM: ATP-NAD/AcoX kinase; SPTR: ATP-NAD/AcoX kinase; PFAM: ATP-NAD kinase. (332 aa)    
Predicted Functional Partners:
Toce_2032
Conserved hypothetical protein; InterPro IPR011719; KEGG: tpd:Teth39_0789 hypothetical protein; PFAM: conserved hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Conserved hypothetical protein (Lin0512_fam); TIGRFAM: conserved hypothetical protein.
 
     0.904
Toce_2028
Catalytic domain of components of various dehydrogenase complexes; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR003016:IPR000089:IPR004167:IPR001078; KEGG: tex:Teth514_2030 dehydrogenase catalytic domain-containing protein; PFAM: catalytic domain of components of various dehydrogenase complexes; biotin/lipoyl attachment domain-containing protein; E3 binding domain protein; SPTR: Catalytic domain of components of various dehydrogenase complexes; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 [...]
 
  
 0.863
pdhA-2
Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
  
 0.817
Toce_2030
Transketolase central region; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR005475:IPR005476; KEGG: tex:Teth514_2032 transketolase, central region; PFAM: Transketolase central region; Transketolase domain protein; SPTR: Transketolase, pyridine binding domain protein; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.
 
  
 0.770
Toce_2027
COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR012999:IPR013027:IPR000815:IPR006258:IPR 004099; KEGG: tex:Teth514_2038 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.
  
  
 0.620
Toce_2033
GAF modulated sigma54 specific transcriptional regulator, Fis family; COGs: COG3284 Transcriptional activator of acetoin/glycerol metabolism; InterProIPR000014:IPR003593:IPR002078:IPR020441:IPR 003018:IPR013767:IPR002197; KEGG: tex:Teth514_2035 fis family GAF modulated sigma54 specific transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; GAF domain protein; PAS fold domain protein; helix-turn-helix Fis-type; SMART: AAA ATPase; PAS domain containing protein; SPTR: GAF modulated sigma54 specific transcriptional regulator, Fis family; PFAM: Bacterial reg [...]
 
   
 0.594
Toce_0791
KEGG: amt:Amet_2095 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Uroporphyrinogen decarboxylase (URO-D).
  
     0.439
pdhA
Dehydrogenase E1 component; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
  
 0.420
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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