| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Toce_0035 | Toce_1588 | Toce_0035 | Toce_1588 | SpoIID/LytB domain protein; COGs: COG2385 Sporulation protein and related protein; InterPro IPR014225:IPR013486:IPR013693:IPR002508; KEGG: aoe:Clos_0281 SpoIID/LytB domain-containing protein; PFAM: cell wall hydrolase/autolysin; Stage II sporulation D domain protein; SMART: cell wall hydrolase/autolysin; SPTR: SpoIID/LytB domain; TIGRFAM: SpoIID/LytB domain protein; stage II sporulation protein D; PFAM: N-acetylmuramoyl-L-alanine amidase; Stage II sporulation protein; TIGRFAM: SpoIID/LytB domain; stage II sporulation protein D. | COGs: COG0438 Glycosyltransferase; InterProIPR001296:IPR013216:IPR001173:IPR019734:IPR 013026:IPR000276; KEGG: tnp:Tnap_0554 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; Methyltransferase type 11; glycosyl transferase group 1; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase family 2; PFAM: Methyltransferase domain; Glycosyl transferases group 1; Glycosyl transferase family 2. | 0.437 |
| Toce_0035 | Toce_2054 | Toce_0035 | Toce_2054 | SpoIID/LytB domain protein; COGs: COG2385 Sporulation protein and related protein; InterPro IPR014225:IPR013486:IPR013693:IPR002508; KEGG: aoe:Clos_0281 SpoIID/LytB domain-containing protein; PFAM: cell wall hydrolase/autolysin; Stage II sporulation D domain protein; SMART: cell wall hydrolase/autolysin; SPTR: SpoIID/LytB domain; TIGRFAM: SpoIID/LytB domain protein; stage II sporulation protein D; PFAM: N-acetylmuramoyl-L-alanine amidase; Stage II sporulation protein; TIGRFAM: SpoIID/LytB domain; stage II sporulation protein D. | Hypothetical protein; KEGG: cbr:CBG00233 C. briggsae CBR-TWK-18 protein; SPTR: Predicted protein. | 0.450 |
| Toce_0439 | Toce_2054 | Toce_0439 | Toce_2054 | InterPro IPR012854; KEGG: cth:Cthe_0402 copper amine oxidase-like protein; PFAM: copper amine oxidase domain protein; SPTR: Copper amine oxidase domain protein; PFAM: Copper amine oxidase N-terminal domain. | Hypothetical protein; KEGG: cbr:CBG00233 C. briggsae CBR-TWK-18 protein; SPTR: Predicted protein. | 0.439 |
| Toce_1588 | Toce_0035 | Toce_1588 | Toce_0035 | COGs: COG0438 Glycosyltransferase; InterProIPR001296:IPR013216:IPR001173:IPR019734:IPR 013026:IPR000276; KEGG: tnp:Tnap_0554 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; Methyltransferase type 11; glycosyl transferase group 1; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase family 2; PFAM: Methyltransferase domain; Glycosyl transferases group 1; Glycosyl transferase family 2. | SpoIID/LytB domain protein; COGs: COG2385 Sporulation protein and related protein; InterPro IPR014225:IPR013486:IPR013693:IPR002508; KEGG: aoe:Clos_0281 SpoIID/LytB domain-containing protein; PFAM: cell wall hydrolase/autolysin; Stage II sporulation D domain protein; SMART: cell wall hydrolase/autolysin; SPTR: SpoIID/LytB domain; TIGRFAM: SpoIID/LytB domain protein; stage II sporulation protein D; PFAM: N-acetylmuramoyl-L-alanine amidase; Stage II sporulation protein; TIGRFAM: SpoIID/LytB domain; stage II sporulation protein D. | 0.437 |
| Toce_1588 | Toce_2054 | Toce_1588 | Toce_2054 | COGs: COG0438 Glycosyltransferase; InterProIPR001296:IPR013216:IPR001173:IPR019734:IPR 013026:IPR000276; KEGG: tnp:Tnap_0554 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; Methyltransferase type 11; glycosyl transferase group 1; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase family 2; PFAM: Methyltransferase domain; Glycosyl transferases group 1; Glycosyl transferase family 2. | Hypothetical protein; KEGG: cbr:CBG00233 C. briggsae CBR-TWK-18 protein; SPTR: Predicted protein. | 0.439 |
| Toce_1786 | Toce_1795 | Toce_1786 | Toce_1795 | Cell wall hydrolase/autolysin; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR012854:IPR002508; KEGG: tit:Thit_0595 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; copper amine oxidase domain protein; SMART: cell wall hydrolase/autolysin; SPTR: N-acetylmuramoyl-L-alanine amidase; PFAM: Copper amine oxidase N-terminal domain; N-acetylmuramoyl-L-alanine amidase; Localisation of periplasmic protein complexes; TIGRFAM: N-acetylmuramoyl-L-alanine amidase CwlD. | Cell wall hydrolase/autolysin; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: bmq:BMQ_0173 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin; SPTR: Cell wall hydrolase/autolysin; PFAM: N-acetylmuramoyl-L-alanine amidase; TIGRFAM: N-acetylmuramoyl-L-alanine amidase CwlD. | 0.924 |
| Toce_1786 | Toce_2054 | Toce_1786 | Toce_2054 | Cell wall hydrolase/autolysin; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR012854:IPR002508; KEGG: tit:Thit_0595 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; copper amine oxidase domain protein; SMART: cell wall hydrolase/autolysin; SPTR: N-acetylmuramoyl-L-alanine amidase; PFAM: Copper amine oxidase N-terminal domain; N-acetylmuramoyl-L-alanine amidase; Localisation of periplasmic protein complexes; TIGRFAM: N-acetylmuramoyl-L-alanine amidase CwlD. | Hypothetical protein; KEGG: cbr:CBG00233 C. briggsae CBR-TWK-18 protein; SPTR: Predicted protein. | 0.439 |
| Toce_1795 | Toce_1786 | Toce_1795 | Toce_1786 | Cell wall hydrolase/autolysin; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: bmq:BMQ_0173 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin; SPTR: Cell wall hydrolase/autolysin; PFAM: N-acetylmuramoyl-L-alanine amidase; TIGRFAM: N-acetylmuramoyl-L-alanine amidase CwlD. | Cell wall hydrolase/autolysin; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR012854:IPR002508; KEGG: tit:Thit_0595 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; copper amine oxidase domain protein; SMART: cell wall hydrolase/autolysin; SPTR: N-acetylmuramoyl-L-alanine amidase; PFAM: Copper amine oxidase N-terminal domain; N-acetylmuramoyl-L-alanine amidase; Localisation of periplasmic protein complexes; TIGRFAM: N-acetylmuramoyl-L-alanine amidase CwlD. | 0.924 |
| Toce_1795 | Toce_2054 | Toce_1795 | Toce_2054 | Cell wall hydrolase/autolysin; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: bmq:BMQ_0173 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin; SPTR: Cell wall hydrolase/autolysin; PFAM: N-acetylmuramoyl-L-alanine amidase; TIGRFAM: N-acetylmuramoyl-L-alanine amidase CwlD. | Hypothetical protein; KEGG: cbr:CBG00233 C. briggsae CBR-TWK-18 protein; SPTR: Predicted protein. | 0.439 |
| Toce_1864 | Toce_1865 | Toce_1864 | Toce_1865 | ABC transporter related protein; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439:IPR003593:IPR017871; KEGG: nth:Nther_2084 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter. | Protein of unknown function DUF214; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: nth:Nther_2083 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: Putative uncharacterized protein; PFAM: Predicted permease. | 0.994 |
| Toce_1864 | Toce_2054 | Toce_1864 | Toce_2054 | ABC transporter related protein; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439:IPR003593:IPR017871; KEGG: nth:Nther_2084 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter. | Hypothetical protein; KEGG: cbr:CBG00233 C. briggsae CBR-TWK-18 protein; SPTR: Predicted protein. | 0.580 |
| Toce_1865 | Toce_1864 | Toce_1865 | Toce_1864 | Protein of unknown function DUF214; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: nth:Nther_2083 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: Putative uncharacterized protein; PFAM: Predicted permease. | ABC transporter related protein; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439:IPR003593:IPR017871; KEGG: nth:Nther_2084 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter. | 0.994 |
| Toce_1865 | Toce_2054 | Toce_1865 | Toce_2054 | Protein of unknown function DUF214; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: nth:Nther_2083 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: Putative uncharacterized protein; PFAM: Predicted permease. | Hypothetical protein; KEGG: cbr:CBG00233 C. briggsae CBR-TWK-18 protein; SPTR: Predicted protein. | 0.793 |
| Toce_1865 | Toce_2165 | Toce_1865 | Toce_2165 | Protein of unknown function DUF214; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: nth:Nther_2083 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: Putative uncharacterized protein; PFAM: Predicted permease. | ABC transporter related protein; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593:IPR017871:IPR003439; KEGG: aoe:Clos_2616 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter. | 0.895 |
| Toce_1865 | macB | Toce_1865 | Toce_2171 | Protein of unknown function DUF214; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: nth:Nther_2083 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: Putative uncharacterized protein; PFAM: Predicted permease. | ABC transporter related protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.895 |
| Toce_2054 | Toce_0035 | Toce_2054 | Toce_0035 | Hypothetical protein; KEGG: cbr:CBG00233 C. briggsae CBR-TWK-18 protein; SPTR: Predicted protein. | SpoIID/LytB domain protein; COGs: COG2385 Sporulation protein and related protein; InterPro IPR014225:IPR013486:IPR013693:IPR002508; KEGG: aoe:Clos_0281 SpoIID/LytB domain-containing protein; PFAM: cell wall hydrolase/autolysin; Stage II sporulation D domain protein; SMART: cell wall hydrolase/autolysin; SPTR: SpoIID/LytB domain; TIGRFAM: SpoIID/LytB domain protein; stage II sporulation protein D; PFAM: N-acetylmuramoyl-L-alanine amidase; Stage II sporulation protein; TIGRFAM: SpoIID/LytB domain; stage II sporulation protein D. | 0.450 |
| Toce_2054 | Toce_0439 | Toce_2054 | Toce_0439 | Hypothetical protein; KEGG: cbr:CBG00233 C. briggsae CBR-TWK-18 protein; SPTR: Predicted protein. | InterPro IPR012854; KEGG: cth:Cthe_0402 copper amine oxidase-like protein; PFAM: copper amine oxidase domain protein; SPTR: Copper amine oxidase domain protein; PFAM: Copper amine oxidase N-terminal domain. | 0.439 |
| Toce_2054 | Toce_1588 | Toce_2054 | Toce_1588 | Hypothetical protein; KEGG: cbr:CBG00233 C. briggsae CBR-TWK-18 protein; SPTR: Predicted protein. | COGs: COG0438 Glycosyltransferase; InterProIPR001296:IPR013216:IPR001173:IPR019734:IPR 013026:IPR000276; KEGG: tnp:Tnap_0554 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; Methyltransferase type 11; glycosyl transferase group 1; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase family 2; PFAM: Methyltransferase domain; Glycosyl transferases group 1; Glycosyl transferase family 2. | 0.439 |
| Toce_2054 | Toce_1786 | Toce_2054 | Toce_1786 | Hypothetical protein; KEGG: cbr:CBG00233 C. briggsae CBR-TWK-18 protein; SPTR: Predicted protein. | Cell wall hydrolase/autolysin; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR012854:IPR002508; KEGG: tit:Thit_0595 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; copper amine oxidase domain protein; SMART: cell wall hydrolase/autolysin; SPTR: N-acetylmuramoyl-L-alanine amidase; PFAM: Copper amine oxidase N-terminal domain; N-acetylmuramoyl-L-alanine amidase; Localisation of periplasmic protein complexes; TIGRFAM: N-acetylmuramoyl-L-alanine amidase CwlD. | 0.439 |
| Toce_2054 | Toce_1795 | Toce_2054 | Toce_1795 | Hypothetical protein; KEGG: cbr:CBG00233 C. briggsae CBR-TWK-18 protein; SPTR: Predicted protein. | Cell wall hydrolase/autolysin; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: bmq:BMQ_0173 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin; SPTR: Cell wall hydrolase/autolysin; PFAM: N-acetylmuramoyl-L-alanine amidase; TIGRFAM: N-acetylmuramoyl-L-alanine amidase CwlD. | 0.439 |