Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Toce_2067COGs: COG0394 Protein-tyrosine-phosphatase; InterPro IPR017867:IPR000106; KEGG: dae:Dtox_4179 protein tyrosine phosphatase; PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight; SPTR: Protein tyrosine phosphatase; PFAM: Low molecular weight phosphotyrosine protein phosphatase. (158 aa)    
Predicted Functional Partners:
Toce_2068
Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.
      0.979
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.966
Toce_2066
COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR004785:IPR003500; KEGG: gyc:GYMC61_3427 sugar-phosphate isomerase, RpiB/LacA/LacB family; PFAM: Ribose/galactose isomerase; PRIAM: Ribose-5-phosphate isomerase; SPTR: Ribose 5-phosphate isomerase; TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: Ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase B; ribose 5-phosphate isomerase; sugar-phosphate isomerases, RpiB/LacA/LacB family.
    
 0.963
Toce_1892
COGs: COG0456 Acetyltransferase; InterPro IPR006464:IPR000182; KEGG: bmq:BMQ_0258 ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: Ribosomal-protein (S18)-alanine acetyltransferase; TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: Acetyltransferase (GNAT) family; TIGRFAM: ribosomal-protein-alanine acetyltransferase.
    
 0.722
mcsB
ATP:guanido phosphotransferase; Catalyzes the specific phosphorylation of arginine residues in proteins.
  
  
 0.720
prfA
Bacterial peptide chain release factor 1 (bRF-1); Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.
  
    0.703
prmC
protein-(glutamine-N5) methyltransferase, release factor-specific; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
     
 0.698
Toce_2073
Protein of unknown function DUF1385; COGs: COG3872 metal-dependent protein; InterPro IPR010787; KEGG: nth:Nther_2873 protein of unknown function DUF1385; PFAM: protein of unknown function DUF1385; SPTR: Putative lipoprotein; PFAM: Protein of unknown function (DUF1385).
       0.697
Toce_0060
Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterProIPR005746:IPR013766:IPR006662:IPR017937:IPR 017936; KEGG: rmr:Rmar_0180 thioredoxin; PFAM: Thioredoxin domain; SPTR: Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin; Belongs to the thioredoxin family.
  
 
 0.695
Toce_1622
COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR013766:IPR017936; KEGG: tte:TTE1880 thiol-disulfide isomerase and thioredoxins; PFAM: Thioredoxin domain; SPTR: Thiol-disulfide isomerase and thioredoxins; PFAM: Thioredoxin; TIGRFAM: thioredoxin; Belongs to the thioredoxin family.
  
 
 0.695
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.