Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Toce_2077Radical SAM domain protein; COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR006638:IPR016431:IPR007197; KEGG: tit:Thit_1756 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily. (337 aa)    
Predicted Functional Partners:
Toce_2078
AMMECR1 domain protein; COGs: COG3885 conserved hypothetical protein; InterPro IPR002733:IPR004183; KEGG: tpd:Teth39_0581 hypothetical protein; PFAM: AMMECR1 domain protein; Extradiol ring-cleavage dioxygenase class III protein subunit B; SPTR: AMMECR1 domain protein; PFAM: AMMECR1; Catalytic LigB subunit of aromatic ring-opening dioxygenase; TIGRFAM: conserved hypothetical protein TIGR00296.
 
     0.956
Toce_0217
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG1251 NAD(P)H-nitrite reductase; InterPro IPR013027:IPR000103; KEGG: hmo:HM1_0433 nad(p)h-nitrite reductase, large subunit protein NirB, putative; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase.
  
  
 0.566
Toce_2075
Cation diffusion facilitator family transporter; COGs: COG0053 Co/Zn/Cd cation transporter; InterPro IPR002524; KEGG: cno:NT01CX_1345 cation efflux family protein, putative; PFAM: cation efflux protein; SPTR: Cation efflux family protein, putative; TIGRFAM: cation diffusion facilitator family transporter; PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
       0.539
Toce_2076
GCN5-related N-acetyltransferase; InterPro IPR000182; KEGG: chy:CHY_1870 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: Putative uncharacterized protein; PFAM: Acetyltransferase (GNAT) family.
       0.539
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
   
  
 0.505
Toce_1216
2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.
 
     0.463
Toce_0214
COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR001670:IPR018211; KEGG: dda:Dd703_3240 iron-containing alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: Iron-containing alcohol dehydrogenase; PFAM: Iron-containing alcohol dehydrogenase.
  
  
 0.452
Toce_1548
COGs: COG1454 Alcohol dehydrogenase class IV; InterPro IPR001670; KEGG: tex:Teth514_0145 iron-containing alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: Iron-containing alcohol dehydrogenase; PFAM: Iron-containing alcohol dehydrogenase.
  
  
 0.452
Toce_0242
NADH dehydrogenase (quinone); COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR011538:IPR019554:IPR019575:IPR017900:IPR 017896; KEGG: csc:Csac_0620 NADH dehydrogenase (quinone); PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH dehydrogenase (Quinone); PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; 4Fe-4S binding domain; Respiratory-chain NADH dehydrogenase 51 Kd subunit; [...]
   
  
 0.432
Toce_0536
NADH dehydrogenase (quinone); COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR017896:IPR017900:IPR001949:IPR011538:IPR 019554:IPR019575; KEGG: cce:Ccel_2304 respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SPTR: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; 4Fe-4 [...]
   
  
 0.432
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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