Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Toce_2082Hypothetical protein; KEGG: sme:SMa1718 AdeC4 adenine deaminase; SPTR: Putative uncharacterized protein. (320 aa)    
Predicted Functional Partners:
Toce_2083
tRNA-U20-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
       0.773
coaX
Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
       0.773
Toce_2085
COGs: COG4684 membrane protein; KEGG: tpd:Teth39_0308 membrane protein-like protein; SPTR: Membrane protein-like protein.
       0.773
Toce_2080
KEGG: tte:TTE2375 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.549
Toce_2081
Helix-turn-helix domain protein; InterPro IPR001387; KEGG: mta:Moth_0148 putative transcriptional regulator; PFAM: helix-turn-helix domain protein; SPTR: Putative uncharacterized protein; PFAM: Helix-turn-helix.
       0.549
Toce_2079
Shikimate/quinate 5-dehydrogenase; COGs: COG5322 dehydrogenase; InterPro IPR006151; KEGG: tit:Thit_2042 shikimate/quinate 5-dehydrogenase; PFAM: Shikimate/quinate 5-dehydrogenase; SPTR: Shikimate/quinate 5-dehydrogenase; PFAM: Shikimate / quinate 5-dehydrogenase.
       0.512
Toce_2086
Rubrerythrin; COGs: COG1592 Rubrerythrin; InterPro IPR003251:IPR009040; KEGG: amt:Amet_0750 rubrerythrin; PFAM: Rubrerythrin; SPTR: Rubrerythrin; PFAM: Rubrerythrin.
       0.420
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (14%) [HD]