| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Toce_0905 | Toce_1071 | Toce_0905 | Toce_1071 | Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | Ribosome biogenesis GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 0.734 |
| Toce_0905 | Toce_2111 | Toce_0905 | Toce_2111 | Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | RNA methyltransferase, TrmH family, group 3; COGs: COG0566 rRNA methylase; InterPro IPR004441:IPR013123:IPR001537; KEGG: cth:Cthe_2060 RNA methyltransferase; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; SPTR: RNA methyltransferase, TrmH family, group 3; TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, putative, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.778 |
| Toce_0905 | mnmE | Toce_0905 | Toce_2280 | Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.797 |
| Toce_0905 | rplC | Toce_0905 | Toce_0119 | Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.812 |
| Toce_0905 | rplK | Toce_0905 | Toce_2103 | Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.759 |
| Toce_0905 | rplM | Toce_0905 | Toce_0153 | Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.777 |
| Toce_0905 | rplQ | Toce_0905 | Toce_0148 | Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | COGs: COG0203 Ribosomal protein L17; InterPro IPR000456; KEGG: tit:Thit_1943 ribosomal protein L17; PFAM: ribosomal protein L17; SPTR: Ribosomal protein L17; TIGRFAM: ribosomal protein L17; PFAM: Ribosomal protein L17; TIGRFAM: ribosomal protein L17. | 0.766 |
| Toce_1071 | Toce_0905 | Toce_1071 | Toce_0905 | Ribosome biogenesis GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.734 |
| Toce_1071 | Toce_2111 | Toce_1071 | Toce_2111 | Ribosome biogenesis GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | RNA methyltransferase, TrmH family, group 3; COGs: COG0566 rRNA methylase; InterPro IPR004441:IPR013123:IPR001537; KEGG: cth:Cthe_2060 RNA methyltransferase; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; SPTR: RNA methyltransferase, TrmH family, group 3; TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, putative, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.843 |
| Toce_1071 | mnmE | Toce_1071 | Toce_2280 | Ribosome biogenesis GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.799 |
| Toce_1071 | rplC | Toce_1071 | Toce_0119 | Ribosome biogenesis GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.838 |
| Toce_1071 | rplK | Toce_1071 | Toce_2103 | Ribosome biogenesis GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.825 |
| Toce_1071 | rplM | Toce_1071 | Toce_0153 | Ribosome biogenesis GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.816 |
| Toce_1071 | rplQ | Toce_1071 | Toce_0148 | Ribosome biogenesis GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | COGs: COG0203 Ribosomal protein L17; InterPro IPR000456; KEGG: tit:Thit_1943 ribosomal protein L17; PFAM: ribosomal protein L17; SPTR: Ribosomal protein L17; TIGRFAM: ribosomal protein L17; PFAM: Ribosomal protein L17; TIGRFAM: ribosomal protein L17. | 0.811 |
| Toce_2110 | Toce_2111 | Toce_2110 | Toce_2111 | Protein of unknown function DUF901; COGs: COG3688 RNA-binding protein containing a PIN domain; InterPro IPR010298; KEGG: aoe:Clos_0474 hypothetical protein; PFAM: protein of unknown function DUF901; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF901). | RNA methyltransferase, TrmH family, group 3; COGs: COG0566 rRNA methylase; InterPro IPR004441:IPR013123:IPR001537; KEGG: cth:Cthe_2060 RNA methyltransferase; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; SPTR: RNA methyltransferase, TrmH family, group 3; TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, putative, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.971 |
| Toce_2110 | cysS | Toce_2110 | Toce_2114 | Protein of unknown function DUF901; COGs: COG3688 RNA-binding protein containing a PIN domain; InterPro IPR010298; KEGG: aoe:Clos_0474 hypothetical protein; PFAM: protein of unknown function DUF901; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF901). | COGs: COG0215 Cysteinyl-tRNA synthetase; InterPro IPR015803:IPR002308:IPR015273; KEGG: tit:Thit_1996 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; PRIAM: Cysteine--tRNA ligase; SPTR: Cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.685 |
| Toce_2110 | mrnC | Toce_2110 | Toce_2113 | Protein of unknown function DUF901; COGs: COG3688 RNA-binding protein containing a PIN domain; InterPro IPR010298; KEGG: aoe:Clos_0474 hypothetical protein; PFAM: protein of unknown function DUF901; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF901). | Ribonuclease III; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. | 0.885 |
| Toce_2111 | Toce_0905 | Toce_2111 | Toce_0905 | RNA methyltransferase, TrmH family, group 3; COGs: COG0566 rRNA methylase; InterPro IPR004441:IPR013123:IPR001537; KEGG: cth:Cthe_2060 RNA methyltransferase; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; SPTR: RNA methyltransferase, TrmH family, group 3; TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, putative, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Pseudouridine synthase, RluA family; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.778 |
| Toce_2111 | Toce_1071 | Toce_2111 | Toce_1071 | RNA methyltransferase, TrmH family, group 3; COGs: COG0566 rRNA methylase; InterPro IPR004441:IPR013123:IPR001537; KEGG: cth:Cthe_2060 RNA methyltransferase; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; SPTR: RNA methyltransferase, TrmH family, group 3; TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, putative, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Ribosome biogenesis GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 0.843 |
| Toce_2111 | Toce_2110 | Toce_2111 | Toce_2110 | RNA methyltransferase, TrmH family, group 3; COGs: COG0566 rRNA methylase; InterPro IPR004441:IPR013123:IPR001537; KEGG: cth:Cthe_2060 RNA methyltransferase; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; SPTR: RNA methyltransferase, TrmH family, group 3; TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, putative, group 3; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Protein of unknown function DUF901; COGs: COG3688 RNA-binding protein containing a PIN domain; InterPro IPR010298; KEGG: aoe:Clos_0474 hypothetical protein; PFAM: protein of unknown function DUF901; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF901). | 0.971 |
