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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Toce_2144Lysine exporter protein (LYSE/YGGA); COGs: COG1280 Putative threonine efflux protein; InterPro IPR001123; KEGG: cbe:Cbei_3178 lysine exporter protein LysE/YggA; PFAM: Lysine exporter protein (LYSE/YGGA); SPTR: Lysine exporter protein (LYSE/YGGA); PFAM: LysE type translocator. (194 aa)    
Predicted Functional Partners:
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
    0.494
Toce_2143
KEGG: hor:Hore_20750 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2508).
       0.485
Toce_2142
pro-sigmaK processing inhibitor BofA; InterPro IPR010001; KEGG: amt:Amet_4774 sigmaK-factor processing regulatory BofA; PFAM: sigmaK-factor processing regulatory BofA; SPTR: SigmaK-factor processing regulatory BofA; TIGRFAM: pro-sigmaK processing inhibitor BofA; PFAM: SigmaK-factor processing regulatory protein BofA; TIGRFAM: pro-sigmaK processing inhibitor BofA.
       0.429
Toce_1029
Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
       0.422
pheT
COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR004532:IPR002547:IPR005146:IPR005147:IPR 005121; KEGG: tit:Thit_1516 phenylalanyl-tRNA synthetase, beta subunit; PFAM: B3/4 domain protein; t-RNA-binding domain protein; tRNA synthetase B5; ferredoxin-fold anticodon-binding; PRIAM: Phenylalanine--tRNA ligase; SPTR: Phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetases class II core domain (F); tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; [...]
       0.422
Toce_2078
AMMECR1 domain protein; COGs: COG3885 conserved hypothetical protein; InterPro IPR002733:IPR004183; KEGG: tpd:Teth39_0581 hypothetical protein; PFAM: AMMECR1 domain protein; Extradiol ring-cleavage dioxygenase class III protein subunit B; SPTR: AMMECR1 domain protein; PFAM: AMMECR1; Catalytic LigB subunit of aromatic ring-opening dioxygenase; TIGRFAM: conserved hypothetical protein TIGR00296.
       0.422
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
       0.402
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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