STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Toce_2164Efflux transporter, RND family, MFP subunit; COGs: COG0845 Membrane-fusion protein; InterPro IPR003997:IPR006143:IPR000089; KEGG: aoe:Clos_2615 RND family efflux transporter MFP subunit; PFAM: biotin/lipoyl attachment domain-containing protein; secretion protein HlyD family protein; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: efflux transporter, RND family, MFP subunit; TIGRFAM: RND family efflux transporter, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (577 aa)    
Predicted Functional Partners:
Toce_2163
Protein of unknown function DUF214; COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: aoe:Clos_2614 hypothetical protein; PFAM: protein of unknown function DUF214; SPTR: Putative uncharacterized protein; PFAM: Predicted permease.
 
 
 0.978
Toce_2167
COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: bbe:BBR47_54170 hypothetical protein; PFAM: outer membrane efflux protein; SPTR: Putative uncharacterized protein; PFAM: Outer membrane efflux protein.
 
 
 0.964
Toce_2172
Protein of unknown function DUF214; COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: tit:Thit_0219 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: Putative uncharacterized protein; PFAM: Predicted permease.
 
 
 0.948
Toce_2168
Acriflavin resistance protein; COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR018073:IPR001036; KEGG: hor:Hore_05050 acriflavin resistance protein; PFAM: acriflavin resistance protein; SPTR: Acriflavin resistance protein; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: heavy metal efflux pump (cobalt-zinc-cadmium); The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
 
 0.917
Toce_2165
ABC transporter related protein; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593:IPR017871:IPR003439; KEGG: aoe:Clos_2616 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter.
 
 
 0.907
macB
ABC transporter related protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
 
 0.812
Toce_0197
S-layer domain protein; InterPro IPR001119; KEGG: tit:Thit_0105 S-layer domain protein; PFAM: S-layer domain protein; SPTR: S-layer domain protein; PFAM: S-layer homology domain.
  
 
 
 0.683
Toce_2233
YycH family protein; COGs: COG4863 conserved hypothetical protein; InterPro IPR009996; KEGG: amt:Amet_4755 hypothetical protein; PFAM: YycH family protein; SPTR: Putative uncharacterized protein; PFAM: YycH protein.
  
     0.592
Toce_2169
Efflux transporter, RND family, MFP subunit; COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR003997:IPR006143; KEGG: mta:Moth_2370 secretion protein HlyD; PFAM: secretion protein HlyD family protein; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
   
0.562
Toce_2232
InterPro IPR018604; KEGG: tit:Thit_2308 protein of unknown function YycH; PFAM: Protein of unknown function YycH; SPTR: Putative uncharacterized protein; PFAM: YycH protein.
  
     0.556
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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