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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Toce_2166Transcriptional regulator, TetR family; COGs: COG1309 Transcriptional regulator; InterPro IPR001647; KEGG: swo:Swol_0177 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: Putative transcriptional regulator, TetR family; PFAM: Bacterial regulatory proteins, tetR family. (204 aa)    
Predicted Functional Partners:
Toce_2168
Acriflavin resistance protein; COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR018073:IPR001036; KEGG: hor:Hore_05050 acriflavin resistance protein; PFAM: acriflavin resistance protein; SPTR: Acriflavin resistance protein; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: heavy metal efflux pump (cobalt-zinc-cadmium); The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
     
 0.810
Toce_2167
COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: bbe:BBR47_54170 hypothetical protein; PFAM: outer membrane efflux protein; SPTR: Putative uncharacterized protein; PFAM: Outer membrane efflux protein.
     
 0.737
Toce_2169
Efflux transporter, RND family, MFP subunit; COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR003997:IPR006143; KEGG: mta:Moth_2370 secretion protein HlyD; PFAM: secretion protein HlyD family protein; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
     
 0.714
Toce_2170
Efflux transporter, RND family, MFP subunit; COGs: COG0845 Membrane-fusion protein; InterPro IPR003997:IPR006143:IPR000089; KEGG: tit:Thit_0217 efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; biotin/lipoyl attachment domain-containing protein; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit.
  
  
 0.664
Toce_2165
ABC transporter related protein; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593:IPR017871:IPR003439; KEGG: aoe:Clos_2616 ABC transporter related; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter.
   
 
 0.544
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
  
    0.537
macB
ABC transporter related protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
   
 
 0.519
Toce_1588
COGs: COG0438 Glycosyltransferase; InterProIPR001296:IPR013216:IPR001173:IPR019734:IPR 013026:IPR000276; KEGG: tnp:Tnap_0554 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; Methyltransferase type 11; glycosyl transferase group 1; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase family 2; PFAM: Methyltransferase domain; Glycosyl transferases group 1; Glycosyl transferase family 2.
  
   
 0.495
Toce_2172
Protein of unknown function DUF214; COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: tit:Thit_0219 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: Putative uncharacterized protein; PFAM: Predicted permease.
     
 0.482
Toce_0372
Diguanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160:IPR003018; KEGG: tte:TTE2335 diguanylate cyclase/phosphodiesterase; PFAM: GGDEF domain containing protein; GAF domain protein; PRIAM: Diguanylate kinase; SMART: GGDEF domain containing protein; GAF domain protein; SPTR: Diguanylate cyclase/phosphodiesterase domain 1 (GGDEF); TIGRFAM: diguanylate cyclase; PFAM: GAF domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
   
 
 0.461
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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