STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Toce_2186TrkA-C domain protein; COGs: COG0490 Putative regulatory ligand-binding protein related to C-terminal domains of K+ channels; InterPro IPR000524:IPR006037; KEGG: tex:Teth514_1200 TrkA domain-containing protein; PFAM: TrkA-C domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: TrkA-C domain protein; PFAM: Bacterial regulatory proteins, gntR family; TrkA-C domain. (206 aa)    
Predicted Functional Partners:
Toce_2187
COGs: COG1125 ABC-type proline/glycine betaine transport systems ATPase components; InterProIPR017871:IPR003439:IPR000644:IPR003593:IPR 005892; KEGG: tit:Thit_1623 glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: ABC transporter related; CBS domain containing protein; SMART: AAA ATPase; CBS domain containing protein; SPTR: Glycine betaine/L-proline ABC transporter, ATPase subunit; TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: ABC transporter; CBS domain; TIGRFAM: glycine betaine/L-proline transport ATP binding subunit.
 
  
 0.680
Toce_2189
COGs: COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein); InterPro IPR007210; KEGG: tex:Teth514_1203 substrate-binding region of ABC-type glycine betaine transport system; PFAM: Substrate-binding region of ABC-type glycine betaine transport system; SPTR: Substrate-binding region of ABC-type glycine betaine transport system; PFAM: Substrate binding domain of ABC-type glycine betaine transport system.
 
     0.543
Toce_2188
COGs: COG1174 ABC-type proline/glycine betaine transport systems permease component; InterPro IPR000515; KEGG: tit:Thit_1622 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.
       0.523
Toce_0935
Protein of unknown function DUF34; COGs: COG3323 conserved hypothetical protein; InterPro IPR002678:IPR017221; KEGG: tit:Thit_1543 protein of unknown function DUF34; PFAM: protein of unknown function DUF34; SPTR: Putative uncharacterized protein; manually curated; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: conserved hypothetical protein TIGR00486; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.
   
    0.489
Toce_2185
KEGG: vsa:VSAL_I1269 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.464
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.437
Toce_1942
Protein of unknown function DUF1524 RloF; InterPro IPR004919:IPR011089; KEGG: eta:ETA_13690 hypothetical protein; PFAM: protein of unknown function DUF1524 RloF; protein of unknown function DUF262; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1524); Protein of unknown function DUF262.
  
     0.429
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.