Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
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Toce_2192NLPA lipoprotein; COGs: COG1464 ABC-type metal ion transport system periplasmic component/surface antigen; InterPro IPR004872; KEGG: tpd:Teth39_1334 YaeC family lipoprotein; PFAM: NLPA lipoprotein; SPTR: Lipoprotein, YaeC family; PFAM: NLPA lipoprotein; TIGRFAM: lipoprotein, YaeC family; Belongs to the nlpA lipoprotein family. (278 aa)    
Predicted Functional Partners:
Toce_2191
Binding-protein-dependent transport systems inner membrane component; COGs: COG2011 ABC-type metal ion transport system permease component; InterPro IPR006140:IPR000515; KEGG: tpd:Teth39_1333 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.
 0.999
metN
ABC transporter related protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.
 
 0.998
Toce_2193
Asp/Glu/hydantoin racemase; InterPro IPR018187:IPR015942; KEGG: tpd:Teth39_1335 Asp/Glu racemase; PFAM: Asp/Glu/hydantoin racemase; SPTR: Asp/Glu racemase; PFAM: Asp/Glu/Hydantoin racemase; Belongs to the aspartate/glutamate racemases family.
       0.732
Toce_1790
COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR006235:IPR000277; KEGG: tpd:Teth39_0501 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; PRIAM: Cysteine synthase; SPTR: O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase.
  
    0.723
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
  
  
 0.541
Toce_0086
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR004017:IPR000759:IPR017900; KEGG: vpa:VP1199 putative glutamate synthase, small chain; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Pyridine nucleotide-disulphide oxidoreductase family protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Cysteine-rich domain.
   
  
 0.472
Toce_2189
COGs: COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein); InterPro IPR007210; KEGG: tex:Teth514_1203 substrate-binding region of ABC-type glycine betaine transport system; PFAM: Substrate-binding region of ABC-type glycine betaine transport system; SPTR: Substrate-binding region of ABC-type glycine betaine transport system; PFAM: Substrate binding domain of ABC-type glycine betaine transport system.
  
  
 0.440
Toce_1572
Extracellular solute-binding protein family 3; COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR001638:IPR001320:IPR018313; KEGG: tte:TTE0512 ABC-type amino acid transport system, periplasmic component; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; ionotropic glutamate receptor; SPTR: ABC-type amino acid transport system, periplasmic component; PFAM: Bacterial extracellular solute-binding proteins, family 3.
  
  
 0.424
Toce_0243
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR001041:IPR013027:IPR006963:IPR006656:IPR 000759:IPR017900:IPR006655:IPR017896; KEGG: aoe:Clos_0277 molybdopterin oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; ferredoxin; molybdopterin oxidoreductase Fe4S4 region; molybdopterin oxidoreductase; SPTR: Molybdopterin oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Molybdopterin oxidoreductase; Molybdopterin oxidoreductase Fe4S4 domain; TIGRFAM: glutamate synt [...]
   
    0.416
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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