| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Toce_0086 | Toce_1790 | Toce_0086 | Toce_1790 | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR004017:IPR000759:IPR017900; KEGG: vpa:VP1199 putative glutamate synthase, small chain; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Pyridine nucleotide-disulphide oxidoreductase family protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Cysteine-rich domain. | COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR006235:IPR000277; KEGG: tpd:Teth39_0501 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; PRIAM: Cysteine synthase; SPTR: O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase. | 0.676 |
| Toce_0086 | Toce_2192 | Toce_0086 | Toce_2192 | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR004017:IPR000759:IPR017900; KEGG: vpa:VP1199 putative glutamate synthase, small chain; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Pyridine nucleotide-disulphide oxidoreductase family protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Cysteine-rich domain. | NLPA lipoprotein; COGs: COG1464 ABC-type metal ion transport system periplasmic component/surface antigen; InterPro IPR004872; KEGG: tpd:Teth39_1334 YaeC family lipoprotein; PFAM: NLPA lipoprotein; SPTR: Lipoprotein, YaeC family; PFAM: NLPA lipoprotein; TIGRFAM: lipoprotein, YaeC family; Belongs to the nlpA lipoprotein family. | 0.450 |
| Toce_1790 | Toce_0086 | Toce_1790 | Toce_0086 | COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR006235:IPR000277; KEGG: tpd:Teth39_0501 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; PRIAM: Cysteine synthase; SPTR: O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase. | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR004017:IPR000759:IPR017900; KEGG: vpa:VP1199 putative glutamate synthase, small chain; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Pyridine nucleotide-disulphide oxidoreductase family protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Cysteine-rich domain. | 0.676 |
| Toce_1790 | Toce_2192 | Toce_1790 | Toce_2192 | COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR006235:IPR000277; KEGG: tpd:Teth39_0501 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; PRIAM: Cysteine synthase; SPTR: O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase. | NLPA lipoprotein; COGs: COG1464 ABC-type metal ion transport system periplasmic component/surface antigen; InterPro IPR004872; KEGG: tpd:Teth39_1334 YaeC family lipoprotein; PFAM: NLPA lipoprotein; SPTR: Lipoprotein, YaeC family; PFAM: NLPA lipoprotein; TIGRFAM: lipoprotein, YaeC family; Belongs to the nlpA lipoprotein family. | 0.703 |
| Toce_2191 | Toce_2192 | Toce_2191 | Toce_2192 | Binding-protein-dependent transport systems inner membrane component; COGs: COG2011 ABC-type metal ion transport system permease component; InterPro IPR006140:IPR000515; KEGG: tpd:Teth39_1333 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component. | NLPA lipoprotein; COGs: COG1464 ABC-type metal ion transport system periplasmic component/surface antigen; InterPro IPR004872; KEGG: tpd:Teth39_1334 YaeC family lipoprotein; PFAM: NLPA lipoprotein; SPTR: Lipoprotein, YaeC family; PFAM: NLPA lipoprotein; TIGRFAM: lipoprotein, YaeC family; Belongs to the nlpA lipoprotein family. | 0.999 |
| Toce_2191 | Toce_2193 | Toce_2191 | Toce_2193 | Binding-protein-dependent transport systems inner membrane component; COGs: COG2011 ABC-type metal ion transport system permease component; InterPro IPR006140:IPR000515; KEGG: tpd:Teth39_1333 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component. | Asp/Glu/hydantoin racemase; InterPro IPR018187:IPR015942; KEGG: tpd:Teth39_1335 Asp/Glu racemase; PFAM: Asp/Glu/hydantoin racemase; SPTR: Asp/Glu racemase; PFAM: Asp/Glu/Hydantoin racemase; Belongs to the aspartate/glutamate racemases family. | 0.627 |
| Toce_2191 | metN | Toce_2191 | Toce_2190 | Binding-protein-dependent transport systems inner membrane component; COGs: COG2011 ABC-type metal ion transport system permease component; InterPro IPR006140:IPR000515; KEGG: tpd:Teth39_1333 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component. | ABC transporter related protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.999 |
| Toce_2192 | Toce_0086 | Toce_2192 | Toce_0086 | NLPA lipoprotein; COGs: COG1464 ABC-type metal ion transport system periplasmic component/surface antigen; InterPro IPR004872; KEGG: tpd:Teth39_1334 YaeC family lipoprotein; PFAM: NLPA lipoprotein; SPTR: Lipoprotein, YaeC family; PFAM: NLPA lipoprotein; TIGRFAM: lipoprotein, YaeC family; Belongs to the nlpA lipoprotein family. | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR004017:IPR000759:IPR017900; KEGG: vpa:VP1199 putative glutamate synthase, small chain; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Pyridine nucleotide-disulphide oxidoreductase family protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Cysteine-rich domain. | 0.450 |
| Toce_2192 | Toce_1790 | Toce_2192 | Toce_1790 | NLPA lipoprotein; COGs: COG1464 ABC-type metal ion transport system periplasmic component/surface antigen; InterPro IPR004872; KEGG: tpd:Teth39_1334 YaeC family lipoprotein; PFAM: NLPA lipoprotein; SPTR: Lipoprotein, YaeC family; PFAM: NLPA lipoprotein; TIGRFAM: lipoprotein, YaeC family; Belongs to the nlpA lipoprotein family. | COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR006235:IPR000277; KEGG: tpd:Teth39_0501 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; PRIAM: Cysteine synthase; SPTR: O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase. | 0.703 |
| Toce_2192 | Toce_2191 | Toce_2192 | Toce_2191 | NLPA lipoprotein; COGs: COG1464 ABC-type metal ion transport system periplasmic component/surface antigen; InterPro IPR004872; KEGG: tpd:Teth39_1334 YaeC family lipoprotein; PFAM: NLPA lipoprotein; SPTR: Lipoprotein, YaeC family; PFAM: NLPA lipoprotein; TIGRFAM: lipoprotein, YaeC family; Belongs to the nlpA lipoprotein family. | Binding-protein-dependent transport systems inner membrane component; COGs: COG2011 ABC-type metal ion transport system permease component; InterPro IPR006140:IPR000515; KEGG: tpd:Teth39_1333 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component. | 0.999 |
| Toce_2192 | Toce_2193 | Toce_2192 | Toce_2193 | NLPA lipoprotein; COGs: COG1464 ABC-type metal ion transport system periplasmic component/surface antigen; InterPro IPR004872; KEGG: tpd:Teth39_1334 YaeC family lipoprotein; PFAM: NLPA lipoprotein; SPTR: Lipoprotein, YaeC family; PFAM: NLPA lipoprotein; TIGRFAM: lipoprotein, YaeC family; Belongs to the nlpA lipoprotein family. | Asp/Glu/hydantoin racemase; InterPro IPR018187:IPR015942; KEGG: tpd:Teth39_1335 Asp/Glu racemase; PFAM: Asp/Glu/hydantoin racemase; SPTR: Asp/Glu racemase; PFAM: Asp/Glu/Hydantoin racemase; Belongs to the aspartate/glutamate racemases family. | 0.734 |
| Toce_2192 | metG | Toce_2192 | Toce_0028 | NLPA lipoprotein; COGs: COG1464 ABC-type metal ion transport system periplasmic component/surface antigen; InterPro IPR004872; KEGG: tpd:Teth39_1334 YaeC family lipoprotein; PFAM: NLPA lipoprotein; SPTR: Lipoprotein, YaeC family; PFAM: NLPA lipoprotein; TIGRFAM: lipoprotein, YaeC family; Belongs to the nlpA lipoprotein family. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.449 |
| Toce_2192 | metK | Toce_2192 | Toce_0367 | NLPA lipoprotein; COGs: COG1464 ABC-type metal ion transport system periplasmic component/surface antigen; InterPro IPR004872; KEGG: tpd:Teth39_1334 YaeC family lipoprotein; PFAM: NLPA lipoprotein; SPTR: Lipoprotein, YaeC family; PFAM: NLPA lipoprotein; TIGRFAM: lipoprotein, YaeC family; Belongs to the nlpA lipoprotein family. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.489 |
| Toce_2192 | metN | Toce_2192 | Toce_2190 | NLPA lipoprotein; COGs: COG1464 ABC-type metal ion transport system periplasmic component/surface antigen; InterPro IPR004872; KEGG: tpd:Teth39_1334 YaeC family lipoprotein; PFAM: NLPA lipoprotein; SPTR: Lipoprotein, YaeC family; PFAM: NLPA lipoprotein; TIGRFAM: lipoprotein, YaeC family; Belongs to the nlpA lipoprotein family. | ABC transporter related protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.999 |
| Toce_2193 | Toce_2191 | Toce_2193 | Toce_2191 | Asp/Glu/hydantoin racemase; InterPro IPR018187:IPR015942; KEGG: tpd:Teth39_1335 Asp/Glu racemase; PFAM: Asp/Glu/hydantoin racemase; SPTR: Asp/Glu racemase; PFAM: Asp/Glu/Hydantoin racemase; Belongs to the aspartate/glutamate racemases family. | Binding-protein-dependent transport systems inner membrane component; COGs: COG2011 ABC-type metal ion transport system permease component; InterPro IPR006140:IPR000515; KEGG: tpd:Teth39_1333 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component. | 0.627 |
| Toce_2193 | Toce_2192 | Toce_2193 | Toce_2192 | Asp/Glu/hydantoin racemase; InterPro IPR018187:IPR015942; KEGG: tpd:Teth39_1335 Asp/Glu racemase; PFAM: Asp/Glu/hydantoin racemase; SPTR: Asp/Glu racemase; PFAM: Asp/Glu/Hydantoin racemase; Belongs to the aspartate/glutamate racemases family. | NLPA lipoprotein; COGs: COG1464 ABC-type metal ion transport system periplasmic component/surface antigen; InterPro IPR004872; KEGG: tpd:Teth39_1334 YaeC family lipoprotein; PFAM: NLPA lipoprotein; SPTR: Lipoprotein, YaeC family; PFAM: NLPA lipoprotein; TIGRFAM: lipoprotein, YaeC family; Belongs to the nlpA lipoprotein family. | 0.734 |
| Toce_2193 | metN | Toce_2193 | Toce_2190 | Asp/Glu/hydantoin racemase; InterPro IPR018187:IPR015942; KEGG: tpd:Teth39_1335 Asp/Glu racemase; PFAM: Asp/Glu/hydantoin racemase; SPTR: Asp/Glu racemase; PFAM: Asp/Glu/Hydantoin racemase; Belongs to the aspartate/glutamate racemases family. | ABC transporter related protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.627 |
| metG | Toce_2192 | Toce_0028 | Toce_2192 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | NLPA lipoprotein; COGs: COG1464 ABC-type metal ion transport system periplasmic component/surface antigen; InterPro IPR004872; KEGG: tpd:Teth39_1334 YaeC family lipoprotein; PFAM: NLPA lipoprotein; SPTR: Lipoprotein, YaeC family; PFAM: NLPA lipoprotein; TIGRFAM: lipoprotein, YaeC family; Belongs to the nlpA lipoprotein family. | 0.449 |
| metG | metK | Toce_0028 | Toce_0367 | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.711 |
| metK | Toce_2192 | Toce_0367 | Toce_2192 | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | NLPA lipoprotein; COGs: COG1464 ABC-type metal ion transport system periplasmic component/surface antigen; InterPro IPR004872; KEGG: tpd:Teth39_1334 YaeC family lipoprotein; PFAM: NLPA lipoprotein; SPTR: Lipoprotein, YaeC family; PFAM: NLPA lipoprotein; TIGRFAM: lipoprotein, YaeC family; Belongs to the nlpA lipoprotein family. | 0.489 |