| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Toce_0040 | Toce_2197 | Toce_0040 | Toce_2197 | Spore coat assembly protein SafA; InterPro IPR014248:IPR018392:IPR002482; KEGG: hor:Hore_21410 peptidoglycan-binding LysM; PFAM: Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM; SPTR: Peptidoglycan-binding LysM; TIGRFAM: spore coat assembly protein SafA; PFAM: LysM domain; TIGRFAM: spore coat assembly protein SafA. | Peptidoglycan-binding domain 1 protein; COGs: COG1520 FOG: WD40-like repeat; InterPro IPR018391:IPR002477:IPR002372; KEGG: chl:Chy400_4120 serine/threonine protein kinase; PFAM: Peptidoglycan-binding domain 1 protein; Pyrrolo-quinoline quinone; SPTR: Similar to beta-propeller protein YxaL; PFAM: Putative peptidoglycan binding domain; PQQ enzyme repeat. | 0.513 |
| Toce_0271 | Toce_2197 | Toce_0271 | Toce_2197 | InterPro IPR011701; KEGG: dge:Dgeo_1065 major facilitator transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily. | Peptidoglycan-binding domain 1 protein; COGs: COG1520 FOG: WD40-like repeat; InterPro IPR018391:IPR002477:IPR002372; KEGG: chl:Chy400_4120 serine/threonine protein kinase; PFAM: Peptidoglycan-binding domain 1 protein; Pyrrolo-quinoline quinone; SPTR: Similar to beta-propeller protein YxaL; PFAM: Putative peptidoglycan binding domain; PQQ enzyme repeat. | 0.500 |
| Toce_1168 | Toce_1588 | Toce_1168 | Toce_1588 | TPR repeat-containing protein; COGs: COG3063 Tfp pilus assembly protein PilF; InterPro IPR019734:IPR001440:IPR013026; KEGG: mth:MTH72 O-linked GlcNAc transferase; PFAM: TPR repeat-containing protein; SPTR: O-linked GlcNAc transferase; PFAM: Coatomer epsilon subunit; Tetratricopeptide repeat. | COGs: COG0438 Glycosyltransferase; InterProIPR001296:IPR013216:IPR001173:IPR019734:IPR 013026:IPR000276; KEGG: tnp:Tnap_0554 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; Methyltransferase type 11; glycosyl transferase group 1; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase family 2; PFAM: Methyltransferase domain; Glycosyl transferases group 1; Glycosyl transferase family 2. | 0.822 |
| Toce_1168 | Toce_2197 | Toce_1168 | Toce_2197 | TPR repeat-containing protein; COGs: COG3063 Tfp pilus assembly protein PilF; InterPro IPR019734:IPR001440:IPR013026; KEGG: mth:MTH72 O-linked GlcNAc transferase; PFAM: TPR repeat-containing protein; SPTR: O-linked GlcNAc transferase; PFAM: Coatomer epsilon subunit; Tetratricopeptide repeat. | Peptidoglycan-binding domain 1 protein; COGs: COG1520 FOG: WD40-like repeat; InterPro IPR018391:IPR002477:IPR002372; KEGG: chl:Chy400_4120 serine/threonine protein kinase; PFAM: Peptidoglycan-binding domain 1 protein; Pyrrolo-quinoline quinone; SPTR: Similar to beta-propeller protein YxaL; PFAM: Putative peptidoglycan binding domain; PQQ enzyme repeat. | 0.493 |
| Toce_1250 | Toce_1588 | Toce_1250 | Toce_1588 | Membrane-associated zinc metalloprotease; COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR004387:IPR008915:IPR001478; KEGG: tte:TTE1401 membrane-associated Zn-dependent protease 1; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Predicted membrane-associated Zn-dependent protease 1; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP. | COGs: COG0438 Glycosyltransferase; InterProIPR001296:IPR013216:IPR001173:IPR019734:IPR 013026:IPR000276; KEGG: tnp:Tnap_0554 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; Methyltransferase type 11; glycosyl transferase group 1; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase family 2; PFAM: Methyltransferase domain; Glycosyl transferases group 1; Glycosyl transferase family 2. | 0.434 |
| Toce_1250 | Toce_2197 | Toce_1250 | Toce_2197 | Membrane-associated zinc metalloprotease; COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR004387:IPR008915:IPR001478; KEGG: tte:TTE1401 membrane-associated Zn-dependent protease 1; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Predicted membrane-associated Zn-dependent protease 1; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP. | Peptidoglycan-binding domain 1 protein; COGs: COG1520 FOG: WD40-like repeat; InterPro IPR018391:IPR002477:IPR002372; KEGG: chl:Chy400_4120 serine/threonine protein kinase; PFAM: Peptidoglycan-binding domain 1 protein; Pyrrolo-quinoline quinone; SPTR: Similar to beta-propeller protein YxaL; PFAM: Putative peptidoglycan binding domain; PQQ enzyme repeat. | 0.510 |
| Toce_1250 | ftsZ | Toce_1250 | Toce_0959 | Membrane-associated zinc metalloprotease; COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR004387:IPR008915:IPR001478; KEGG: tte:TTE1401 membrane-associated Zn-dependent protease 1; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Predicted membrane-associated Zn-dependent protease 1; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.443 |
| Toce_1250 | prsA | Toce_1250 | Toce_1076 | Membrane-associated zinc metalloprotease; COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR004387:IPR008915:IPR001478; KEGG: tte:TTE1401 membrane-associated Zn-dependent protease 1; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Predicted membrane-associated Zn-dependent protease 1; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP. | PpiC-type peptidyl-prolyl cis-trans isomerase; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins. | 0.431 |
| Toce_1588 | Toce_1168 | Toce_1588 | Toce_1168 | COGs: COG0438 Glycosyltransferase; InterProIPR001296:IPR013216:IPR001173:IPR019734:IPR 013026:IPR000276; KEGG: tnp:Tnap_0554 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; Methyltransferase type 11; glycosyl transferase group 1; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase family 2; PFAM: Methyltransferase domain; Glycosyl transferases group 1; Glycosyl transferase family 2. | TPR repeat-containing protein; COGs: COG3063 Tfp pilus assembly protein PilF; InterPro IPR019734:IPR001440:IPR013026; KEGG: mth:MTH72 O-linked GlcNAc transferase; PFAM: TPR repeat-containing protein; SPTR: O-linked GlcNAc transferase; PFAM: Coatomer epsilon subunit; Tetratricopeptide repeat. | 0.822 |
| Toce_1588 | Toce_1250 | Toce_1588 | Toce_1250 | COGs: COG0438 Glycosyltransferase; InterProIPR001296:IPR013216:IPR001173:IPR019734:IPR 013026:IPR000276; KEGG: tnp:Tnap_0554 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; Methyltransferase type 11; glycosyl transferase group 1; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase family 2; PFAM: Methyltransferase domain; Glycosyl transferases group 1; Glycosyl transferase family 2. | Membrane-associated zinc metalloprotease; COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR004387:IPR008915:IPR001478; KEGG: tte:TTE1401 membrane-associated Zn-dependent protease 1; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Predicted membrane-associated Zn-dependent protease 1; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP. | 0.434 |
| Toce_1588 | Toce_2197 | Toce_1588 | Toce_2197 | COGs: COG0438 Glycosyltransferase; InterProIPR001296:IPR013216:IPR001173:IPR019734:IPR 013026:IPR000276; KEGG: tnp:Tnap_0554 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; Methyltransferase type 11; glycosyl transferase group 1; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase family 2; PFAM: Methyltransferase domain; Glycosyl transferases group 1; Glycosyl transferase family 2. | Peptidoglycan-binding domain 1 protein; COGs: COG1520 FOG: WD40-like repeat; InterPro IPR018391:IPR002477:IPR002372; KEGG: chl:Chy400_4120 serine/threonine protein kinase; PFAM: Peptidoglycan-binding domain 1 protein; Pyrrolo-quinoline quinone; SPTR: Similar to beta-propeller protein YxaL; PFAM: Putative peptidoglycan binding domain; PQQ enzyme repeat. | 0.592 |
| Toce_1588 | ftsZ | Toce_1588 | Toce_0959 | COGs: COG0438 Glycosyltransferase; InterProIPR001296:IPR013216:IPR001173:IPR019734:IPR 013026:IPR000276; KEGG: tnp:Tnap_0554 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; Methyltransferase type 11; glycosyl transferase group 1; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase family 2; PFAM: Methyltransferase domain; Glycosyl transferases group 1; Glycosyl transferase family 2. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.475 |
| Toce_1588 | ispH | Toce_1588 | Toce_1156 | COGs: COG0438 Glycosyltransferase; InterProIPR001296:IPR013216:IPR001173:IPR019734:IPR 013026:IPR000276; KEGG: tnp:Tnap_0554 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; Methyltransferase type 11; glycosyl transferase group 1; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase family 2; PFAM: Methyltransferase domain; Glycosyl transferases group 1; Glycosyl transferase family 2. | Hydroxymethylbutenyl pyrophosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.699 |
| Toce_1731 | Toce_2197 | Toce_1731 | Toce_2197 | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG1252 NADH dehydrogenase FAD-containing subunit; InterPro IPR013027:IPR011637; KEGG: hor:Hore_14860 NADH dehydrogenase, FAD-containing subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; DoxX family protein; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; DoxX. | Peptidoglycan-binding domain 1 protein; COGs: COG1520 FOG: WD40-like repeat; InterPro IPR018391:IPR002477:IPR002372; KEGG: chl:Chy400_4120 serine/threonine protein kinase; PFAM: Peptidoglycan-binding domain 1 protein; Pyrrolo-quinoline quinone; SPTR: Similar to beta-propeller protein YxaL; PFAM: Putative peptidoglycan binding domain; PQQ enzyme repeat. | 0.501 |
| Toce_2197 | Toce_0040 | Toce_2197 | Toce_0040 | Peptidoglycan-binding domain 1 protein; COGs: COG1520 FOG: WD40-like repeat; InterPro IPR018391:IPR002477:IPR002372; KEGG: chl:Chy400_4120 serine/threonine protein kinase; PFAM: Peptidoglycan-binding domain 1 protein; Pyrrolo-quinoline quinone; SPTR: Similar to beta-propeller protein YxaL; PFAM: Putative peptidoglycan binding domain; PQQ enzyme repeat. | Spore coat assembly protein SafA; InterPro IPR014248:IPR018392:IPR002482; KEGG: hor:Hore_21410 peptidoglycan-binding LysM; PFAM: Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM; SPTR: Peptidoglycan-binding LysM; TIGRFAM: spore coat assembly protein SafA; PFAM: LysM domain; TIGRFAM: spore coat assembly protein SafA. | 0.513 |
| Toce_2197 | Toce_0271 | Toce_2197 | Toce_0271 | Peptidoglycan-binding domain 1 protein; COGs: COG1520 FOG: WD40-like repeat; InterPro IPR018391:IPR002477:IPR002372; KEGG: chl:Chy400_4120 serine/threonine protein kinase; PFAM: Peptidoglycan-binding domain 1 protein; Pyrrolo-quinoline quinone; SPTR: Similar to beta-propeller protein YxaL; PFAM: Putative peptidoglycan binding domain; PQQ enzyme repeat. | InterPro IPR011701; KEGG: dge:Dgeo_1065 major facilitator transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily. | 0.500 |
| Toce_2197 | Toce_1168 | Toce_2197 | Toce_1168 | Peptidoglycan-binding domain 1 protein; COGs: COG1520 FOG: WD40-like repeat; InterPro IPR018391:IPR002477:IPR002372; KEGG: chl:Chy400_4120 serine/threonine protein kinase; PFAM: Peptidoglycan-binding domain 1 protein; Pyrrolo-quinoline quinone; SPTR: Similar to beta-propeller protein YxaL; PFAM: Putative peptidoglycan binding domain; PQQ enzyme repeat. | TPR repeat-containing protein; COGs: COG3063 Tfp pilus assembly protein PilF; InterPro IPR019734:IPR001440:IPR013026; KEGG: mth:MTH72 O-linked GlcNAc transferase; PFAM: TPR repeat-containing protein; SPTR: O-linked GlcNAc transferase; PFAM: Coatomer epsilon subunit; Tetratricopeptide repeat. | 0.493 |
| Toce_2197 | Toce_1250 | Toce_2197 | Toce_1250 | Peptidoglycan-binding domain 1 protein; COGs: COG1520 FOG: WD40-like repeat; InterPro IPR018391:IPR002477:IPR002372; KEGG: chl:Chy400_4120 serine/threonine protein kinase; PFAM: Peptidoglycan-binding domain 1 protein; Pyrrolo-quinoline quinone; SPTR: Similar to beta-propeller protein YxaL; PFAM: Putative peptidoglycan binding domain; PQQ enzyme repeat. | Membrane-associated zinc metalloprotease; COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR004387:IPR008915:IPR001478; KEGG: tte:TTE1401 membrane-associated Zn-dependent protease 1; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Predicted membrane-associated Zn-dependent protease 1; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP. | 0.510 |
| Toce_2197 | Toce_1588 | Toce_2197 | Toce_1588 | Peptidoglycan-binding domain 1 protein; COGs: COG1520 FOG: WD40-like repeat; InterPro IPR018391:IPR002477:IPR002372; KEGG: chl:Chy400_4120 serine/threonine protein kinase; PFAM: Peptidoglycan-binding domain 1 protein; Pyrrolo-quinoline quinone; SPTR: Similar to beta-propeller protein YxaL; PFAM: Putative peptidoglycan binding domain; PQQ enzyme repeat. | COGs: COG0438 Glycosyltransferase; InterProIPR001296:IPR013216:IPR001173:IPR019734:IPR 013026:IPR000276; KEGG: tnp:Tnap_0554 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; Methyltransferase type 11; glycosyl transferase group 1; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase family 2; PFAM: Methyltransferase domain; Glycosyl transferases group 1; Glycosyl transferase family 2. | 0.592 |
| Toce_2197 | Toce_1731 | Toce_2197 | Toce_1731 | Peptidoglycan-binding domain 1 protein; COGs: COG1520 FOG: WD40-like repeat; InterPro IPR018391:IPR002477:IPR002372; KEGG: chl:Chy400_4120 serine/threonine protein kinase; PFAM: Peptidoglycan-binding domain 1 protein; Pyrrolo-quinoline quinone; SPTR: Similar to beta-propeller protein YxaL; PFAM: Putative peptidoglycan binding domain; PQQ enzyme repeat. | FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG1252 NADH dehydrogenase FAD-containing subunit; InterPro IPR013027:IPR011637; KEGG: hor:Hore_14860 NADH dehydrogenase, FAD-containing subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; DoxX family protein; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; DoxX. | 0.501 |