STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Toce_2211Protein of unknown function DUF6 transmembrane; COGs: COG2510 membrane protein; InterPro IPR000620; KEGG: aoe:Clos_0838 hypothetical protein; PFAM: protein of unknown function DUF6 transmembrane; SPTR: Putative uncharacterized protein; PFAM: EamA-like transporter family. (138 aa)    
Predicted Functional Partners:
Toce_2210
Transcriptional regulator, GntR family; COGs: COG1802 Transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: cce:Ccel_2175 transcriptional regulator, GntR family; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; FCD domain.
       0.512
Toce_0479
tRNA pseudouridine synthase D TruD; COGs: COG0585 conserved hypothetical protein; InterPro IPR011760:IPR020119:IPR001656; KEGG: csc:Csac_1232 tRNA pseudouridine synthase D, TruD; PFAM: tRNA pseudouridine synthase D TruD; SPTR: tRNA pseudouridine synthase D, TruD; PFAM: tRNA pseudouridine synthase D (TruD); TIGRFAM: conserved hypothetical protein TIGR00094.
  
     0.510
bpsA
Protein of unknown function DUF43; Involved in the biosynthesis of branched-chain polyamines, which support the growth of thermophiles under high-temperature conditions. Catalyzes the sequential condensation of spermidine with the aminopropyl groups of decarboxylated S-adenosylmethionines to produce N(4)-bis(aminopropyl)spermidine via N(4)-aminopropylspermidine.
  
     0.439
hslO
Hsp33 protein; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress.
  
    0.422
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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