| node1 | node2 | node1 annotation | node2 annotation | score |
| Toce_0199 | Toce_1159 | COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: bcl:ABC3884 stage 0 sporulation protein F; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain. | MCP methyltransferase, CheR-type; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterPro IPR000780; KEGG: amt:Amet_2623 protein-glutamate O-methyltransferase; PFAM: MCP methyltransferase CheR-type; PRIAM: Protein-glutamate O-methyltransferase; SMART: MCP methyltransferase CheR-type; SPTR: Protein-glutamate O-methyltransferase; PFAM: CheR methyltransferase, SAM binding domain; CheR methyltransferase, all-alpha domain. | 0.570 |
| Toce_0199 | Toce_2235 | COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: bcl:ABC3884 stage 0 sporulation protein F; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain. | COGs: COG5002 Signal transduction histidine kinase; InterProIPR005467:IPR000014:IPR003660:IPR003661:IPR 003594:IPR004358:IPR013767; KEGG: aoe:Clos_2783 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS domain containing protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: HAMP domain; Histid [...] | 0.752 |
| Toce_0285 | Toce_2235 | Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: dae:Dtox_2625 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. | COGs: COG5002 Signal transduction histidine kinase; InterProIPR005467:IPR000014:IPR003660:IPR003661:IPR 003594:IPR004358:IPR013767; KEGG: aoe:Clos_2783 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS domain containing protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: HAMP domain; Histid [...] | 0.914 |
| Toce_0967 | Toce_2235 | Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: chy:CHY_2047 DNA-binding response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: DNA-binding response regulator; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal; TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB. | COGs: COG5002 Signal transduction histidine kinase; InterProIPR005467:IPR000014:IPR003660:IPR003661:IPR 003594:IPR004358:IPR013767; KEGG: aoe:Clos_2783 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS domain containing protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: HAMP domain; Histid [...] | 0.984 |
| Toce_1159 | Toce_0199 | MCP methyltransferase, CheR-type; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterPro IPR000780; KEGG: amt:Amet_2623 protein-glutamate O-methyltransferase; PFAM: MCP methyltransferase CheR-type; PRIAM: Protein-glutamate O-methyltransferase; SMART: MCP methyltransferase CheR-type; SPTR: Protein-glutamate O-methyltransferase; PFAM: CheR methyltransferase, SAM binding domain; CheR methyltransferase, all-alpha domain. | COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: bcl:ABC3884 stage 0 sporulation protein F; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain. | 0.570 |
| Toce_1159 | Toce_2235 | MCP methyltransferase, CheR-type; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterPro IPR000780; KEGG: amt:Amet_2623 protein-glutamate O-methyltransferase; PFAM: MCP methyltransferase CheR-type; PRIAM: Protein-glutamate O-methyltransferase; SMART: MCP methyltransferase CheR-type; SPTR: Protein-glutamate O-methyltransferase; PFAM: CheR methyltransferase, SAM binding domain; CheR methyltransferase, all-alpha domain. | COGs: COG5002 Signal transduction histidine kinase; InterProIPR005467:IPR000014:IPR003660:IPR003661:IPR 003594:IPR004358:IPR013767; KEGG: aoe:Clos_2783 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS domain containing protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: HAMP domain; Histid [...] | 0.904 |
| Toce_1455 | Toce_2235 | Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: mta:Moth_0827 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. | COGs: COG5002 Signal transduction histidine kinase; InterProIPR005467:IPR000014:IPR003660:IPR003661:IPR 003594:IPR004358:IPR013767; KEGG: aoe:Clos_2783 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS domain containing protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: HAMP domain; Histid [...] | 0.881 |
| Toce_2003 | Toce_2235 | Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: chy:CHY_2567 DNA-binding response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: DNA-binding response regulator; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. | COGs: COG5002 Signal transduction histidine kinase; InterProIPR005467:IPR000014:IPR003660:IPR003661:IPR 003594:IPR004358:IPR013767; KEGG: aoe:Clos_2783 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS domain containing protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: HAMP domain; Histid [...] | 0.908 |
| Toce_2231 | Toce_2232 | InterPro IPR012854; KEGG: dae:Dtox_3690 copper amine oxidase domain protein; PFAM: copper amine oxidase domain protein; SPTR: Copper amine oxidase domain protein; PFAM: Copper amine oxidase N-terminal domain. | InterPro IPR018604; KEGG: tit:Thit_2308 protein of unknown function YycH; PFAM: Protein of unknown function YycH; SPTR: Putative uncharacterized protein; PFAM: YycH protein. | 0.838 |
| Toce_2231 | Toce_2233 | InterPro IPR012854; KEGG: dae:Dtox_3690 copper amine oxidase domain protein; PFAM: copper amine oxidase domain protein; SPTR: Copper amine oxidase domain protein; PFAM: Copper amine oxidase N-terminal domain. | YycH family protein; COGs: COG4863 conserved hypothetical protein; InterPro IPR009996; KEGG: amt:Amet_4755 hypothetical protein; PFAM: YycH family protein; SPTR: Putative uncharacterized protein; PFAM: YycH protein. | 0.741 |
| Toce_2231 | Toce_2235 | InterPro IPR012854; KEGG: dae:Dtox_3690 copper amine oxidase domain protein; PFAM: copper amine oxidase domain protein; SPTR: Copper amine oxidase domain protein; PFAM: Copper amine oxidase N-terminal domain. | COGs: COG5002 Signal transduction histidine kinase; InterProIPR005467:IPR000014:IPR003660:IPR003661:IPR 003594:IPR004358:IPR013767; KEGG: aoe:Clos_2783 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS domain containing protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: HAMP domain; Histid [...] | 0.680 |
| Toce_2231 | Toce_2236 | InterPro IPR012854; KEGG: dae:Dtox_3690 copper amine oxidase domain protein; PFAM: copper amine oxidase domain protein; SPTR: Copper amine oxidase domain protein; PFAM: Copper amine oxidase N-terminal domain. | Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: cth:Cthe_2333 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. | 0.458 |
| Toce_2232 | Toce_2231 | InterPro IPR018604; KEGG: tit:Thit_2308 protein of unknown function YycH; PFAM: Protein of unknown function YycH; SPTR: Putative uncharacterized protein; PFAM: YycH protein. | InterPro IPR012854; KEGG: dae:Dtox_3690 copper amine oxidase domain protein; PFAM: copper amine oxidase domain protein; SPTR: Copper amine oxidase domain protein; PFAM: Copper amine oxidase N-terminal domain. | 0.838 |
| Toce_2232 | Toce_2233 | InterPro IPR018604; KEGG: tit:Thit_2308 protein of unknown function YycH; PFAM: Protein of unknown function YycH; SPTR: Putative uncharacterized protein; PFAM: YycH protein. | YycH family protein; COGs: COG4863 conserved hypothetical protein; InterPro IPR009996; KEGG: amt:Amet_4755 hypothetical protein; PFAM: YycH family protein; SPTR: Putative uncharacterized protein; PFAM: YycH protein. | 0.976 |
| Toce_2232 | Toce_2235 | InterPro IPR018604; KEGG: tit:Thit_2308 protein of unknown function YycH; PFAM: Protein of unknown function YycH; SPTR: Putative uncharacterized protein; PFAM: YycH protein. | COGs: COG5002 Signal transduction histidine kinase; InterProIPR005467:IPR000014:IPR003660:IPR003661:IPR 003594:IPR004358:IPR013767; KEGG: aoe:Clos_2783 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS domain containing protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: HAMP domain; Histid [...] | 0.803 |
| Toce_2232 | Toce_2236 | InterPro IPR018604; KEGG: tit:Thit_2308 protein of unknown function YycH; PFAM: Protein of unknown function YycH; SPTR: Putative uncharacterized protein; PFAM: YycH protein. | Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: cth:Cthe_2333 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. | 0.597 |
| Toce_2233 | Toce_2231 | YycH family protein; COGs: COG4863 conserved hypothetical protein; InterPro IPR009996; KEGG: amt:Amet_4755 hypothetical protein; PFAM: YycH family protein; SPTR: Putative uncharacterized protein; PFAM: YycH protein. | InterPro IPR012854; KEGG: dae:Dtox_3690 copper amine oxidase domain protein; PFAM: copper amine oxidase domain protein; SPTR: Copper amine oxidase domain protein; PFAM: Copper amine oxidase N-terminal domain. | 0.741 |
| Toce_2233 | Toce_2232 | YycH family protein; COGs: COG4863 conserved hypothetical protein; InterPro IPR009996; KEGG: amt:Amet_4755 hypothetical protein; PFAM: YycH family protein; SPTR: Putative uncharacterized protein; PFAM: YycH protein. | InterPro IPR018604; KEGG: tit:Thit_2308 protein of unknown function YycH; PFAM: Protein of unknown function YycH; SPTR: Putative uncharacterized protein; PFAM: YycH protein. | 0.976 |
| Toce_2233 | Toce_2235 | YycH family protein; COGs: COG4863 conserved hypothetical protein; InterPro IPR009996; KEGG: amt:Amet_4755 hypothetical protein; PFAM: YycH family protein; SPTR: Putative uncharacterized protein; PFAM: YycH protein. | COGs: COG5002 Signal transduction histidine kinase; InterProIPR005467:IPR000014:IPR003660:IPR003661:IPR 003594:IPR004358:IPR013767; KEGG: aoe:Clos_2783 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS domain containing protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: HAMP domain; Histid [...] | 0.803 |
| Toce_2233 | Toce_2236 | YycH family protein; COGs: COG4863 conserved hypothetical protein; InterPro IPR009996; KEGG: amt:Amet_4755 hypothetical protein; PFAM: YycH family protein; SPTR: Putative uncharacterized protein; PFAM: YycH protein. | Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: cth:Cthe_2333 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal. | 0.562 |