Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Toce_2259COGs: COG0668 Small-conductance mechanosensitive channel; InterPro IPR006685; KEGG: amt:Amet_0029 MscS mechanosensitive ion channel; PFAM: MscS Mechanosensitive ion channel; SPTR: MscS Mechanosensitive ion channel; PFAM: Mechanosensitive ion channel. (284 aa)    
Predicted Functional Partners:
Toce_2258
Protein of unknown function DUF951; COGs: COG4481 conserved hypothetical protein; InterPro IPR009296; KEGG: cth:Cthe_2512 hypothetical protein; PFAM: protein of unknown function DUF951; SPTR: Putative uncharacterized protein; PFAM: Bacterial protein of unknown function (DUF951).
       0.826
Toce_2260
Selenium metabolism protein YedF; InterPro IPR001455:IPR019870; KEGG: tte:TTE1883 transcriptional regulator; PFAM: SirA family protein; SPTR: Predicted Transcriptional regulator; TIGRFAM: selenium metabolism protein YedF; PFAM: SirA-like protein; TIGRFAM: selenium metabolism protein YedF; Belongs to the sulfur carrier protein TusA family.
       0.786
rpsF
SSU ribosomal protein S6P; Binds together with S18 to 16S ribosomal RNA.
       0.660
Toce_2256
COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424:IPR011344; KEGG: nth:Nther_2915 single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: Single-stranded DNA-binding protein; TIGRFAM: single-strand binding protein; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb).
       0.648
Toce_2261
Colicin V production protein; InterPro IPR003825; KEGG: pth:PTH_2906 hypothetical protein; PFAM: Colicin V production protein; SPTR: Colicin V production protein; PFAM: Colicin V production protein.
       0.634
rpsR
SSU ribosomal protein S18P; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.
  
    0.633
Toce_2250
Transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR018335:IPR000595:IPR012318:IPR001808; KEGG: aoe:Clos_2132 Crp/FNR family transcriptional regulator; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp; SPTR: Transcriptional regulator, Crp/Fnr family; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain.
  
  
 0.557
Toce_2254
COGs: COG4241 membrane protein; InterPro IPR018710; KEGG: aco:Amico_1419 protein of unknown function DUF2232, membrane; PFAM: Protein of unknown function DUF2232, membrane; SPTR: Membrane protein-like; PFAM: Predicted membrane protein (DUF2232).
       0.544
rplI
LSU ribosomal protein L9P; Binds to the 23S rRNA.
       0.536
Toce_2253
COGs: COG3887 signaling protein consisting of a modified GGDEF domain and a DHH domain; InterPro IPR000160:IPR001667:IPR003156; KEGG: aoe:Clos_2799 phosphoesterase domain-containing protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase RecJ domain protein; PFAM: DHH family; DHHA1 domain.
       0.529
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (6%) [HD]