| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Toce_2250 | Toce_2253 | Toce_2250 | Toce_2253 | Transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR018335:IPR000595:IPR012318:IPR001808; KEGG: aoe:Clos_2132 Crp/FNR family transcriptional regulator; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp; SPTR: Transcriptional regulator, Crp/Fnr family; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain. | COGs: COG3887 signaling protein consisting of a modified GGDEF domain and a DHH domain; InterPro IPR000160:IPR001667:IPR003156; KEGG: aoe:Clos_2799 phosphoesterase domain-containing protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase RecJ domain protein; PFAM: DHH family; DHHA1 domain. | 0.709 |
| Toce_2250 | Toce_2254 | Toce_2250 | Toce_2254 | Transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR018335:IPR000595:IPR012318:IPR001808; KEGG: aoe:Clos_2132 Crp/FNR family transcriptional regulator; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp; SPTR: Transcriptional regulator, Crp/Fnr family; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain. | COGs: COG4241 membrane protein; InterPro IPR018710; KEGG: aco:Amico_1419 protein of unknown function DUF2232, membrane; PFAM: Protein of unknown function DUF2232, membrane; SPTR: Membrane protein-like; PFAM: Predicted membrane protein (DUF2232). | 0.675 |
| Toce_2250 | Toce_2256 | Toce_2250 | Toce_2256 | Transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR018335:IPR000595:IPR012318:IPR001808; KEGG: aoe:Clos_2132 Crp/FNR family transcriptional regulator; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp; SPTR: Transcriptional regulator, Crp/Fnr family; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain. | COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424:IPR011344; KEGG: nth:Nther_2915 single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: Single-stranded DNA-binding protein; TIGRFAM: single-strand binding protein; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb). | 0.511 |
| Toce_2250 | Toce_2258 | Toce_2250 | Toce_2258 | Transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR018335:IPR000595:IPR012318:IPR001808; KEGG: aoe:Clos_2132 Crp/FNR family transcriptional regulator; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp; SPTR: Transcriptional regulator, Crp/Fnr family; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain. | Protein of unknown function DUF951; COGs: COG4481 conserved hypothetical protein; InterPro IPR009296; KEGG: cth:Cthe_2512 hypothetical protein; PFAM: protein of unknown function DUF951; SPTR: Putative uncharacterized protein; PFAM: Bacterial protein of unknown function (DUF951). | 0.434 |
| Toce_2250 | Toce_2259 | Toce_2250 | Toce_2259 | Transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR018335:IPR000595:IPR012318:IPR001808; KEGG: aoe:Clos_2132 Crp/FNR family transcriptional regulator; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp; SPTR: Transcriptional regulator, Crp/Fnr family; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain. | COGs: COG0668 Small-conductance mechanosensitive channel; InterPro IPR006685; KEGG: amt:Amet_0029 MscS mechanosensitive ion channel; PFAM: MscS Mechanosensitive ion channel; SPTR: MscS Mechanosensitive ion channel; PFAM: Mechanosensitive ion channel. | 0.557 |
| Toce_2250 | rplI | Toce_2250 | Toce_2252 | Transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR018335:IPR000595:IPR012318:IPR001808; KEGG: aoe:Clos_2132 Crp/FNR family transcriptional regulator; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp; SPTR: Transcriptional regulator, Crp/Fnr family; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain. | LSU ribosomal protein L9P; Binds to the 23S rRNA. | 0.709 |
| Toce_2250 | rpsF | Toce_2250 | Toce_2257 | Transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR018335:IPR000595:IPR012318:IPR001808; KEGG: aoe:Clos_2132 Crp/FNR family transcriptional regulator; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp; SPTR: Transcriptional regulator, Crp/Fnr family; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain. | SSU ribosomal protein S6P; Binds together with S18 to 16S ribosomal RNA. | 0.560 |
| Toce_2250 | rpsR | Toce_2250 | Toce_2255 | Transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR018335:IPR000595:IPR012318:IPR001808; KEGG: aoe:Clos_2132 Crp/FNR family transcriptional regulator; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp; SPTR: Transcriptional regulator, Crp/Fnr family; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain. | SSU ribosomal protein S18P; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. | 0.559 |
| Toce_2253 | Toce_2250 | Toce_2253 | Toce_2250 | COGs: COG3887 signaling protein consisting of a modified GGDEF domain and a DHH domain; InterPro IPR000160:IPR001667:IPR003156; KEGG: aoe:Clos_2799 phosphoesterase domain-containing protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase RecJ domain protein; PFAM: DHH family; DHHA1 domain. | Transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR018335:IPR000595:IPR012318:IPR001808; KEGG: aoe:Clos_2132 Crp/FNR family transcriptional regulator; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp; SPTR: Transcriptional regulator, Crp/Fnr family; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain. | 0.709 |
| Toce_2253 | Toce_2254 | Toce_2253 | Toce_2254 | COGs: COG3887 signaling protein consisting of a modified GGDEF domain and a DHH domain; InterPro IPR000160:IPR001667:IPR003156; KEGG: aoe:Clos_2799 phosphoesterase domain-containing protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase RecJ domain protein; PFAM: DHH family; DHHA1 domain. | COGs: COG4241 membrane protein; InterPro IPR018710; KEGG: aco:Amico_1419 protein of unknown function DUF2232, membrane; PFAM: Protein of unknown function DUF2232, membrane; SPTR: Membrane protein-like; PFAM: Predicted membrane protein (DUF2232). | 0.845 |
| Toce_2253 | Toce_2256 | Toce_2253 | Toce_2256 | COGs: COG3887 signaling protein consisting of a modified GGDEF domain and a DHH domain; InterPro IPR000160:IPR001667:IPR003156; KEGG: aoe:Clos_2799 phosphoesterase domain-containing protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase RecJ domain protein; PFAM: DHH family; DHHA1 domain. | COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424:IPR011344; KEGG: nth:Nther_2915 single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: Single-stranded DNA-binding protein; TIGRFAM: single-strand binding protein; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb). | 0.647 |
| Toce_2253 | Toce_2258 | Toce_2253 | Toce_2258 | COGs: COG3887 signaling protein consisting of a modified GGDEF domain and a DHH domain; InterPro IPR000160:IPR001667:IPR003156; KEGG: aoe:Clos_2799 phosphoesterase domain-containing protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase RecJ domain protein; PFAM: DHH family; DHHA1 domain. | Protein of unknown function DUF951; COGs: COG4481 conserved hypothetical protein; InterPro IPR009296; KEGG: cth:Cthe_2512 hypothetical protein; PFAM: protein of unknown function DUF951; SPTR: Putative uncharacterized protein; PFAM: Bacterial protein of unknown function (DUF951). | 0.715 |
| Toce_2253 | Toce_2259 | Toce_2253 | Toce_2259 | COGs: COG3887 signaling protein consisting of a modified GGDEF domain and a DHH domain; InterPro IPR000160:IPR001667:IPR003156; KEGG: aoe:Clos_2799 phosphoesterase domain-containing protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase RecJ domain protein; PFAM: DHH family; DHHA1 domain. | COGs: COG0668 Small-conductance mechanosensitive channel; InterPro IPR006685; KEGG: amt:Amet_0029 MscS mechanosensitive ion channel; PFAM: MscS Mechanosensitive ion channel; SPTR: MscS Mechanosensitive ion channel; PFAM: Mechanosensitive ion channel. | 0.529 |
| Toce_2253 | Toce_2260 | Toce_2253 | Toce_2260 | COGs: COG3887 signaling protein consisting of a modified GGDEF domain and a DHH domain; InterPro IPR000160:IPR001667:IPR003156; KEGG: aoe:Clos_2799 phosphoesterase domain-containing protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase RecJ domain protein; PFAM: DHH family; DHHA1 domain. | Selenium metabolism protein YedF; InterPro IPR001455:IPR019870; KEGG: tte:TTE1883 transcriptional regulator; PFAM: SirA family protein; SPTR: Predicted Transcriptional regulator; TIGRFAM: selenium metabolism protein YedF; PFAM: SirA-like protein; TIGRFAM: selenium metabolism protein YedF; Belongs to the sulfur carrier protein TusA family. | 0.438 |
| Toce_2253 | rplI | Toce_2253 | Toce_2252 | COGs: COG3887 signaling protein consisting of a modified GGDEF domain and a DHH domain; InterPro IPR000160:IPR001667:IPR003156; KEGG: aoe:Clos_2799 phosphoesterase domain-containing protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase RecJ domain protein; PFAM: DHH family; DHHA1 domain. | LSU ribosomal protein L9P; Binds to the 23S rRNA. | 0.988 |
| Toce_2253 | rpsF | Toce_2253 | Toce_2257 | COGs: COG3887 signaling protein consisting of a modified GGDEF domain and a DHH domain; InterPro IPR000160:IPR001667:IPR003156; KEGG: aoe:Clos_2799 phosphoesterase domain-containing protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase RecJ domain protein; PFAM: DHH family; DHHA1 domain. | SSU ribosomal protein S6P; Binds together with S18 to 16S ribosomal RNA. | 0.635 |
| Toce_2253 | rpsR | Toce_2253 | Toce_2255 | COGs: COG3887 signaling protein consisting of a modified GGDEF domain and a DHH domain; InterPro IPR000160:IPR001667:IPR003156; KEGG: aoe:Clos_2799 phosphoesterase domain-containing protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase RecJ domain protein; PFAM: DHH family; DHHA1 domain. | SSU ribosomal protein S18P; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. | 0.674 |
| Toce_2254 | Toce_2250 | Toce_2254 | Toce_2250 | COGs: COG4241 membrane protein; InterPro IPR018710; KEGG: aco:Amico_1419 protein of unknown function DUF2232, membrane; PFAM: Protein of unknown function DUF2232, membrane; SPTR: Membrane protein-like; PFAM: Predicted membrane protein (DUF2232). | Transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR018335:IPR000595:IPR012318:IPR001808; KEGG: aoe:Clos_2132 Crp/FNR family transcriptional regulator; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp; SPTR: Transcriptional regulator, Crp/Fnr family; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain. | 0.675 |
| Toce_2254 | Toce_2253 | Toce_2254 | Toce_2253 | COGs: COG4241 membrane protein; InterPro IPR018710; KEGG: aco:Amico_1419 protein of unknown function DUF2232, membrane; PFAM: Protein of unknown function DUF2232, membrane; SPTR: Membrane protein-like; PFAM: Predicted membrane protein (DUF2232). | COGs: COG3887 signaling protein consisting of a modified GGDEF domain and a DHH domain; InterPro IPR000160:IPR001667:IPR003156; KEGG: aoe:Clos_2799 phosphoesterase domain-containing protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase RecJ domain protein; PFAM: DHH family; DHHA1 domain. | 0.845 |
| Toce_2254 | Toce_2256 | Toce_2254 | Toce_2256 | COGs: COG4241 membrane protein; InterPro IPR018710; KEGG: aco:Amico_1419 protein of unknown function DUF2232, membrane; PFAM: Protein of unknown function DUF2232, membrane; SPTR: Membrane protein-like; PFAM: Predicted membrane protein (DUF2232). | COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424:IPR011344; KEGG: nth:Nther_2915 single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: Single-stranded DNA-binding protein; TIGRFAM: single-strand binding protein; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb). | 0.671 |