Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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Toce_2260Selenium metabolism protein YedF; InterPro IPR001455:IPR019870; KEGG: tte:TTE1883 transcriptional regulator; PFAM: SirA family protein; SPTR: Predicted Transcriptional regulator; TIGRFAM: selenium metabolism protein YedF; PFAM: SirA-like protein; TIGRFAM: selenium metabolism protein YedF; Belongs to the sulfur carrier protein TusA family. (201 aa)    
Predicted Functional Partners:
selD
Selenophosphate synthase; Synthesizes selenophosphate from selenide and ATP.
 
   
 0.868
Toce_2258
Protein of unknown function DUF951; COGs: COG4481 conserved hypothetical protein; InterPro IPR009296; KEGG: cth:Cthe_2512 hypothetical protein; PFAM: protein of unknown function DUF951; SPTR: Putative uncharacterized protein; PFAM: Bacterial protein of unknown function (DUF951).
       0.786
Toce_2259
COGs: COG0668 Small-conductance mechanosensitive channel; InterPro IPR006685; KEGG: amt:Amet_0029 MscS mechanosensitive ion channel; PFAM: MscS Mechanosensitive ion channel; SPTR: MscS Mechanosensitive ion channel; PFAM: Mechanosensitive ion channel.
       0.786
iscS
Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
   
 
 0.776
Toce_1465
Aminotransferase class V; COGs: COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR000192:IPR016454:IPR020578; KEGG: tte:TTE1663 cysteine sulfinate desulfinase/cysteine desulfurase; PFAM: aminotransferase class V; SPTR: Aminotransferase class V; PFAM: Aminotransferase class-V.
   
 
 0.776
Toce_2271
Cysteine desulfurase family protein; COGs: COG0520 Selenocysteine lyase; InterPro IPR010969:IPR000192; KEGG: tte:TTE2789 selenocysteine lyase; PFAM: aminotransferase class V; SPTR: Selenocysteine lyase; TIGRFAM: cysteine desulfurase family protein; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase family protein.
 
 
 
 0.753
Toce_0775
COGs: COG3276 Selenocysteine-specific translation elongation factor; InterProIPR005225:IPR004535:IPR000795:IPR004161:IPR 015190:IPR015191; KEGG: pth:PTH_1427 selenocysteine-specific translation elongation factor; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; Elongation factor SelB winged helix 2; Elongation factor SelB winged helix 3; PRIAM: Sulfate adenylyltransferase; SPTR: Selenocysteine-specific translation elongation factor; TIGRFAM: selenocysteine-specific translation elongation factor; small GTP-binding protein; PFAM: Elongation factor Tu dom [...]
 
   
 0.734
Toce_1716
COGs: COG1775 Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit BcrC/BadD/HgdB; InterPro IPR010327; KEGG: cbf:CLI_3383 putative R-2-hydroxyglutaryl-CoA dehydratase subunit; PFAM: 2-hydroxyglutaryl-CoA dehydratase D-component; SPTR: Putative uncharacterized protein; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component.
 
    0.731
selA
L-seryl-tRNA selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.
 
  
 0.649
Toce_2261
Colicin V production protein; InterPro IPR003825; KEGG: pth:PTH_2906 hypothetical protein; PFAM: Colicin V production protein; SPTR: Colicin V production protein; PFAM: Colicin V production protein.
       0.643
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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