Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Toce_2268Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: tte:TTE0841 membrane proteins related to metalloendopeptidase; PFAM: Peptidase M23; SPTR: M23 peptidase domain protein; PFAM: Peptidase family M23. (304 aa)    
Predicted Functional Partners:
Toce_2267
Protein of unknown function DUF583; COGs: COG1664 Integral membrane protein CcmA involved in cell shape determination; InterPro IPR007607; KEGG: tit:Thit_0787 protein of unknown function DUF583; PFAM: protein of unknown function DUF583; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function, DUF583.
 
   
 0.885
Toce_1110
COGs: COG1776 Chemotaxis protein CheC inhibitor of MCP methylation; InterPro IPR001172:IPR007597:IPR001543:IPR012826; KEGG: tte:TTE1429 flagellar motor switch protein; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein; SPTR: Chemotaxis protein CheC, inhibitor of MCP methylation; TIGRFAM: flagellar motor switch protein FliN; PFAM: Surface presentation of antigens (SPOA); CheC-like family; TIGRFAM: flagellar motor switch protein FliN.
   
   0.690
Toce_1390
Penicillin-binding protein, 1A family; COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR011816:IPR001264:IPR001460:IPR002119; KEGG: chy:CHY_1563 1A family penicillin-binding protein; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; SPTR: Penicillin-binding protein, 1A family; TIGRFAM: penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family.
  
  
 0.680
Toce_2269
KEGG: cbl:CLK_3121 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.675
Toce_2266
Diacylglycerol kinase catalytic region; COGs: COG1597 Sphingosine kinase; InterPro IPR001206:IPR005218; KEGG: diacylglycerol kinase catalytic region; PFAM: diacylglycerol kinase catalytic region; SMART: diacylglycerol kinase catalytic region; SPTR: Diacylglycerol kinase catalytic region; PFAM: Diacylglycerol kinase catalytic domain; TIGRFAM: conserved protein of unknown function cotranscribed with Bmr (bmrU).
       0.646
Toce_2264
InterPro IPR005370; KEGG: cce:Ccel_3466 protein of unknown function UPF0180; PFAM: protein of unknown function UPF0180; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised protein family (UPF0180).
       0.593
Toce_2265
KEGG: aoe:Clos_2863 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.591
Toce_2270
Protein of unknown function DUF554; COGs: COG1811 Uncharacterized membrane protein possible Na+ channel or pump; InterPro IPR007563; KEGG: dhd:Dhaf_4952 protein of unknown function DUF554; PFAM: protein of unknown function DUF554; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF554).
       0.577
Toce_2271
Cysteine desulfurase family protein; COGs: COG0520 Selenocysteine lyase; InterPro IPR010969:IPR000192; KEGG: tte:TTE2789 selenocysteine lyase; PFAM: aminotransferase class V; SPTR: Selenocysteine lyase; TIGRFAM: cysteine desulfurase family protein; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase family protein.
       0.496
Toce_1378
SpoIID/LytB domain protein; COGs: COG2385 Sporulation protein and related protein; InterPro IPR013486:IPR013693; KEGG: tit:Thit_1008 SpoIID/LytB domain protein; PFAM: Stage II sporulation D domain protein; SPTR: SpoIID/LytB domain protein; TIGRFAM: SpoIID/LytB domain protein; PFAM: Stage II sporulation protein; TIGRFAM: SpoIID/LytB domain.
 
   
 0.461
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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