Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Toce_2271Cysteine desulfurase family protein; COGs: COG0520 Selenocysteine lyase; InterPro IPR010969:IPR000192; KEGG: tte:TTE2789 selenocysteine lyase; PFAM: aminotransferase class V; SPTR: Selenocysteine lyase; TIGRFAM: cysteine desulfurase family protein; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase family protein. (381 aa)    
Predicted Functional Partners:
Toce_1131
FeS cluster assembly scaffold protein NifU; COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR002871:IPR017787; KEGG: chy:CHY_2198 putative FeS assembly protein; PFAM: nitrogen-fixing NifU domain protein; SPTR: Putative FeS assembly protein; TIGRFAM: FeS cluster assembly scaffold protein NifU; PFAM: NifU-like N terminal domain; TIGRFAM: FeS cluster assembly scaffold IscU; FeS cluster assembly scaffold protein NifU, Clostridium type.
  
 
 0.990
Toce_0538
FeS cluster assembly scaffold protein NifU; COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR017787:IPR002871; KEGG: mta:Moth_1651 nitrogen-fixing NifU-like; PFAM: nitrogen-fixing NifU domain protein; SPTR: Nitrogen-fixing NifU-like; TIGRFAM: FeS cluster assembly scaffold protein NifU; PFAM: NifU-like N terminal domain; TIGRFAM: FeS cluster assembly scaffold protein NifU, Clostridium type.
  
 
 0.958
Toce_2260
Selenium metabolism protein YedF; InterPro IPR001455:IPR019870; KEGG: tte:TTE1883 transcriptional regulator; PFAM: SirA family protein; SPTR: Predicted Transcriptional regulator; TIGRFAM: selenium metabolism protein YedF; PFAM: SirA-like protein; TIGRFAM: selenium metabolism protein YedF; Belongs to the sulfur carrier protein TusA family.
 
 
 
 0.753
Toce_2270
Protein of unknown function DUF554; COGs: COG1811 Uncharacterized membrane protein possible Na+ channel or pump; InterPro IPR007563; KEGG: dhd:Dhaf_4952 protein of unknown function DUF554; PFAM: protein of unknown function DUF554; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF554).
       0.723
Toce_2269
KEGG: cbl:CLK_3121 hypothetical protein; SPTR: Putative uncharacterized protein.
     
 0.668
selD
Selenophosphate synthase; Synthesizes selenophosphate from selenide and ATP.
   
 0.586
Toce_2272
Radical SAM domain protein; COGs: COG0502 Biotin synthase; InterPro IPR006638:IPR005244:IPR007197; KEGG: amt:Amet_4104 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily; Protein of unknown function (DUF3343).
     
 0.565
Toce_2273
Iron-only hydrogenase maturation protein HydG; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR007197:IPR010722; KEGG: tpd:Teth39_1703 thiamine biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; SPTR: Biotin and thiamin synthesis associated; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: thiazole biosynthesis protein ThiH.
     
 0.533
Toce_2268
Peptidase M23; COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: tte:TTE0841 membrane proteins related to metalloendopeptidase; PFAM: Peptidase M23; SPTR: M23 peptidase domain protein; PFAM: Peptidase family M23.
       0.496
Toce_2267
Protein of unknown function DUF583; COGs: COG1664 Integral membrane protein CcmA involved in cell shape determination; InterPro IPR007607; KEGG: tit:Thit_0787 protein of unknown function DUF583; PFAM: protein of unknown function DUF583; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function, DUF583.
       0.490
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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