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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Toce_2272Radical SAM domain protein; COGs: COG0502 Biotin synthase; InterPro IPR006638:IPR005244:IPR007197; KEGG: amt:Amet_4104 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily; Protein of unknown function (DUF3343). (426 aa)    
Predicted Functional Partners:
Toce_1972
Iron-only hydrogenase maturation protein HydF; COGs: COG1160 GTPase; InterPro IPR001806:IPR005225:IPR002917; KEGG: tpd:Teth39_0245 small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; SPTR: Small GTP-binding protein; TIGRFAM: small GTP-binding protein; PFAM: GTPase of unknown function; TIGRFAM: small GTP-binding protein domain.
   
 0.989
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
 
 0.977
Toce_2273
Iron-only hydrogenase maturation protein HydG; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR007197:IPR010722; KEGG: tpd:Teth39_1703 thiamine biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; SPTR: Biotin and thiamin synthesis associated; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: thiazole biosynthesis protein ThiH.
 
  
0.931
Toce_0697
NAD(P)-dependent iron-only hydrogenase catalytic subunit; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR001041:IPR017896:IPR013352:IPR017900:IPR 019574:IPR004108:IPR003149; KEGG: csc:Csac_1864 hydrogenase, Fe-only; PFAM: hydrogenase large subunit domain protein; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; iron hydrogenase small subunit; SPTR: Hydrogenase, Fe-only; TIGRFAM: hydrogenase, Fe-only; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Iron only hydrogenase large subunit, C-terminal domain; NADH-ubiquinone oxidor [...]
 
  
 0.878
Toce_1010
KEGG: tte:TTE1595 hypothetical protein; SPTR: Putative uncharacterized protein.
 
  
 0.849
Toce_0786
Hydrogenase, Fe-only; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR017896:IPR013352:IPR017900:IPR004108:IPR 003149; KEGG: sth:STH3293 iron hydrogenase; PFAM: hydrogenase large subunit domain protein; iron hydrogenase small subunit; PRIAM: Ferredoxin hydrogenase; SPTR: Iron hydrogenase; TIGRFAM: hydrogenase, Fe-only; PFAM: Iron only hydrogenase large subunit, C-terminal domain; Iron hydrogenase small subunit; TIGRFAM: hydrogenases, Fe-only.
 
  
 0.784
Toce_0537
NAD(P)-dependent iron-only hydrogenase catalytic subunit; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR001041:IPR017896:IPR017900:IPR000283:IPR 013352:IPR019574:IPR004108:IPR003149; KEGG: hor:Hore_01810 NADH dehydrogenase I subunit G; PFAM: hydrogenase large subunit domain protein; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; iron hydrogenase small subunit; SPTR: NADH dehydrogenase I subunit G; TIGRFAM: hydrogenase, Fe-only; PFAM: Iron only hydrogenase large subunit, C-terminal domain; NADH-ubiquinone oxidoreductase-G i [...]
 
  
 0.754
Toce_0243
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR001041:IPR013027:IPR006963:IPR006656:IPR 000759:IPR017900:IPR006655:IPR017896; KEGG: aoe:Clos_0277 molybdopterin oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; ferredoxin; molybdopterin oxidoreductase Fe4S4 region; molybdopterin oxidoreductase; SPTR: Molybdopterin oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Molybdopterin oxidoreductase; Molybdopterin oxidoreductase Fe4S4 domain; TIGRFAM: glutamate synt [...]
     
 0.727
Toce_0733
BioY protein; COGs: COG1268 conserved hypothetical protein; InterPro IPR003784; KEGG: tte:TTE0777 uncharacterized ACR; PFAM: BioY protein; SPTR: Uncharacterized ACR; PFAM: BioY family.
  
  
 0.687
Toce_1471
COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterPro IPR004108:IPR017896:IPR017900; KEGG: dae:Dtox_1708 hydrogenase large subunit domain protein; PFAM: hydrogenase large subunit domain protein; SPTR: Hydrogenase large subunit domain protein; PFAM: Iron only hydrogenase large subunit, C-terminal domain; 4Fe-4S binding domain.
 
  
 0.679
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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