Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Toce_2273Iron-only hydrogenase maturation protein HydG; COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR007197:IPR010722; KEGG: tpd:Teth39_1703 thiamine biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; SPTR: Biotin and thiamin synthesis associated; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: thiazole biosynthesis protein ThiH. (476 aa)    
Predicted Functional Partners:
Toce_1972
Iron-only hydrogenase maturation protein HydF; COGs: COG1160 GTPase; InterPro IPR001806:IPR005225:IPR002917; KEGG: tpd:Teth39_0245 small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; SPTR: Small GTP-binding protein; TIGRFAM: small GTP-binding protein; PFAM: GTPase of unknown function; TIGRFAM: small GTP-binding protein domain.
  
 0.970
Toce_2272
Radical SAM domain protein; COGs: COG0502 Biotin synthase; InterPro IPR006638:IPR005244:IPR007197; KEGG: amt:Amet_4104 radical SAM domain-containing protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily; Protein of unknown function (DUF3343).
 
  
0.924
thiE
Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.897
Toce_1817
thiamineS protein; InterPro IPR003749; KEGG: tit:Thit_0461 thiamineS protein; PFAM: thiamineS protein; SPTR: ThiamineS protein; PFAM: ThiS family.
  
  
 0.795
Toce_1092
Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
   
    0.791
Toce_1541
Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR010822:IPR001932; KEGG: mta:Moth_0392 serine phosphatase; PFAM: Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; SPTR: Serine phosphatase; PFAM: Stage II sporulation protein E (SpoIIE).
   
    0.791
Toce_1010
KEGG: tte:TTE1595 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.790
Toce_0697
NAD(P)-dependent iron-only hydrogenase catalytic subunit; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR001041:IPR017896:IPR013352:IPR017900:IPR 019574:IPR004108:IPR003149; KEGG: csc:Csac_1864 hydrogenase, Fe-only; PFAM: hydrogenase large subunit domain protein; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; iron hydrogenase small subunit; SPTR: Hydrogenase, Fe-only; TIGRFAM: hydrogenase, Fe-only; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Iron only hydrogenase large subunit, C-terminal domain; NADH-ubiquinone oxidor [...]
 
   
 0.776
Toce_0786
Hydrogenase, Fe-only; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR017896:IPR013352:IPR017900:IPR004108:IPR 003149; KEGG: sth:STH3293 iron hydrogenase; PFAM: hydrogenase large subunit domain protein; iron hydrogenase small subunit; PRIAM: Ferredoxin hydrogenase; SPTR: Iron hydrogenase; TIGRFAM: hydrogenase, Fe-only; PFAM: Iron only hydrogenase large subunit, C-terminal domain; Iron hydrogenase small subunit; TIGRFAM: hydrogenases, Fe-only.
 
   
 0.721
Toce_1540
Anti-anti-sigma factor; InterPro IPR003658:IPR002645; KEGG: mta:Moth_0393 anti-sigma-factor antagonist domain-containing protein; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma-factor antagonist (STAS) domain protein; TIGRFAM: anti-anti-sigma factor; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor.
  
    0.721
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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