close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Toce_2274COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089:IPR000683; KEGG: tit:Thit_0641 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; oxidoreductase domain protein; SMART: chemotaxis sensory transducer; SPTR: Methyl-accepting chemotaxis sensory transducer; manually curated; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Methyl-accepting chemotaxis protein (MCP) signaling domain. (286 aa)    
Predicted Functional Partners:
Toce_1121
CheA signal transduction histidine kinase; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR008207:IPR003594:IPR002545:IPR004358:IPR 010808:IPR004105:IPR005467; KEGG: tpd:Teth39_1232 CheA signal transduction histidine kinase; PFAM: CheW domain protein; P2 response regulator binding domain protein; Hpt domain protein; Signal transducing histidine kinase homodimeric; ATP-binding region ATPase domain protein; SMART: CheW domain protein; Hpt domain protein; ATP-binding region ATPase domain protein; SPTR: CheA signal transduction histidine kinase; PFAM: CheW- [...]
 
 
 0.981
Toce_0470
CheW protein; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: tte:TTE0700 chemotaxis signal transduction protein; PFAM: CheW domain protein; SMART: CheW domain protein; SPTR: Chemotaxis signal transduction protein; PFAM: CheW-like domain.
 
 
 0.966
Toce_1122
CheW protein; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: nth:Nther_1419 CheW protein; PFAM: CheW domain protein; SMART: CheW domain protein; SPTR: CheW protein; PFAM: CheW-like domain.
 
 
 0.966
Toce_1159
MCP methyltransferase, CheR-type; COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterPro IPR000780; KEGG: amt:Amet_2623 protein-glutamate O-methyltransferase; PFAM: MCP methyltransferase CheR-type; PRIAM: Protein-glutamate O-methyltransferase; SMART: MCP methyltransferase CheR-type; SPTR: Protein-glutamate O-methyltransferase; PFAM: CheR methyltransferase, SAM binding domain; CheR methyltransferase, all-alpha domain.
 
 
 0.894
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 
 0.876
cheD
CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
 
 0.778
Toce_1110
COGs: COG1776 Chemotaxis protein CheC inhibitor of MCP methylation; InterPro IPR001172:IPR007597:IPR001543:IPR012826; KEGG: tte:TTE1429 flagellar motor switch protein; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein; SPTR: Chemotaxis protein CheC, inhibitor of MCP methylation; TIGRFAM: flagellar motor switch protein FliN; PFAM: Surface presentation of antigens (SPOA); CheC-like family; TIGRFAM: flagellar motor switch protein FliN.
  
 
 0.696
Toce_0372
Diguanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160:IPR003018; KEGG: tte:TTE2335 diguanylate cyclase/phosphodiesterase; PFAM: GGDEF domain containing protein; GAF domain protein; PRIAM: Diguanylate kinase; SMART: GGDEF domain containing protein; GAF domain protein; SPTR: Diguanylate cyclase/phosphodiesterase domain 1 (GGDEF); TIGRFAM: diguanylate cyclase; PFAM: GAF domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
  
 
 0.612
Toce_2276
COGs: COG1192 ATPase involved in chromosome partitioning; KEGG: cth:Cthe_2377 chromosome segregation ATPase; SPTR: Chromosome segregation ATPase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain.
  
  
 0.591
Toce_0460
Response regulator receiver protein; COGs: COG0784 FOG: CheY-like receiver; InterPro IPR001789:IPR013972; KEGG: cbe:Cbei_4174 response regulator receiver; PFAM: YcbB domain protein; response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver; PFAM: Response regulator receiver domain; YcbB domain.
 
 
 0.576
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (34%) [HD]