| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Toce_2275 | Toce_2276 | Toce_2275 | Toce_2276 | Chromosome segregation DNA-binding protein; COGs: COG1475 transcriptional regulator protein; InterPro IPR003115:IPR004437; KEGG: tpd:Teth39_2284 ParB-like partition protein; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: ParB-like partition protein; TIGRFAM: parB-like partition protein; PFAM: Helix-turn-helix; ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins; Belongs to the ParB family. | COGs: COG1192 ATPase involved in chromosome partitioning; KEGG: cth:Cthe_2377 chromosome segregation ATPase; SPTR: Chromosome segregation ATPase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain. | 0.999 |
| Toce_2275 | Toce_2277 | Toce_2275 | Toce_2277 | Chromosome segregation DNA-binding protein; COGs: COG1475 transcriptional regulator protein; InterPro IPR003115:IPR004437; KEGG: tpd:Teth39_2284 ParB-like partition protein; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: ParB-like partition protein; TIGRFAM: parB-like partition protein; PFAM: Helix-turn-helix; ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins; Belongs to the ParB family. | ParB family protein; COGs: COG1475 transcriptional regulator protein; InterPro IPR003115:IPR004437; KEGG: tte:TTE2792 transcriptional regulator; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: Predicted Transcriptional regulator; TIGRFAM: parB-like partition protein; PFAM: ParB-like nuclease domain; KorB domain; TIGRFAM: ParB-like partition proteins; Belongs to the ParB family. | 0.896 |
| Toce_2275 | Toce_2282 | Toce_2275 | Toce_2282 | Chromosome segregation DNA-binding protein; COGs: COG1475 transcriptional regulator protein; InterPro IPR003115:IPR004437; KEGG: tpd:Teth39_2284 ParB-like partition protein; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: ParB-like partition protein; TIGRFAM: parB-like partition protein; PFAM: Helix-turn-helix; ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins; Belongs to the ParB family. | Membrane protein insertase, YidC/Oxa1 family; COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR001708:IPR020001; KEGG: tpd:Teth39_2292 60 kDa inner membrane insertion protein; PFAM: 60 kDa inner membrane insertion protein; SPTR: 60 kDa inner membrane insertion protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family; PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain. | 0.685 |
| Toce_2275 | dnaA | Toce_2275 | Toce_0001 | Chromosome segregation DNA-binding protein; COGs: COG1475 transcriptional regulator protein; InterPro IPR003115:IPR004437; KEGG: tpd:Teth39_2284 ParB-like partition protein; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: ParB-like partition protein; TIGRFAM: parB-like partition protein; PFAM: Helix-turn-helix; ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins; Belongs to the ParB family. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.697 |
| Toce_2275 | rsmG | Toce_2275 | Toce_2278 | Chromosome segregation DNA-binding protein; COGs: COG1475 transcriptional regulator protein; InterPro IPR003115:IPR004437; KEGG: tpd:Teth39_2284 ParB-like partition protein; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: ParB-like partition protein; TIGRFAM: parB-like partition protein; PFAM: Helix-turn-helix; ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins; Belongs to the ParB family. | Methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | 0.874 |
| Toce_2275 | topA | Toce_2275 | Toce_1085 | Chromosome segregation DNA-binding protein; COGs: COG1475 transcriptional regulator protein; InterPro IPR003115:IPR004437; KEGG: tpd:Teth39_2284 ParB-like partition protein; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: ParB-like partition protein; TIGRFAM: parB-like partition protein; PFAM: Helix-turn-helix; ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins; Belongs to the ParB family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.600 |
| Toce_2276 | Toce_2275 | Toce_2276 | Toce_2275 | COGs: COG1192 ATPase involved in chromosome partitioning; KEGG: cth:Cthe_2377 chromosome segregation ATPase; SPTR: Chromosome segregation ATPase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain. | Chromosome segregation DNA-binding protein; COGs: COG1475 transcriptional regulator protein; InterPro IPR003115:IPR004437; KEGG: tpd:Teth39_2284 ParB-like partition protein; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: ParB-like partition protein; TIGRFAM: parB-like partition protein; PFAM: Helix-turn-helix; ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins; Belongs to the ParB family. | 0.999 |
| Toce_2276 | Toce_2277 | Toce_2276 | Toce_2277 | COGs: COG1192 ATPase involved in chromosome partitioning; KEGG: cth:Cthe_2377 chromosome segregation ATPase; SPTR: Chromosome segregation ATPase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain. | ParB family protein; COGs: COG1475 transcriptional regulator protein; InterPro IPR003115:IPR004437; KEGG: tte:TTE2792 transcriptional regulator; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: Predicted Transcriptional regulator; TIGRFAM: parB-like partition protein; PFAM: ParB-like nuclease domain; KorB domain; TIGRFAM: ParB-like partition proteins; Belongs to the ParB family. | 0.993 |
| Toce_2276 | Toce_2282 | Toce_2276 | Toce_2282 | COGs: COG1192 ATPase involved in chromosome partitioning; KEGG: cth:Cthe_2377 chromosome segregation ATPase; SPTR: Chromosome segregation ATPase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain. | Membrane protein insertase, YidC/Oxa1 family; COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR001708:IPR020001; KEGG: tpd:Teth39_2292 60 kDa inner membrane insertion protein; PFAM: 60 kDa inner membrane insertion protein; SPTR: 60 kDa inner membrane insertion protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family; PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain. | 0.669 |
| Toce_2276 | birA | Toce_2276 | Toce_0887 | COGs: COG1192 ATPase involved in chromosome partitioning; KEGG: cth:Cthe_2377 chromosome segregation ATPase; SPTR: Chromosome segregation ATPase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.767 |
| Toce_2276 | dnaA | Toce_2276 | Toce_0001 | COGs: COG1192 ATPase involved in chromosome partitioning; KEGG: cth:Cthe_2377 chromosome segregation ATPase; SPTR: Chromosome segregation ATPase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.739 |
| Toce_2276 | ffh | Toce_2276 | Toce_1065 | COGs: COG1192 ATPase involved in chromosome partitioning; KEGG: cth:Cthe_2377 chromosome segregation ATPase; SPTR: Chromosome segregation ATPase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain. | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.649 |
| Toce_2276 | guaB | Toce_2276 | Toce_2129 | COGs: COG1192 ATPase involved in chromosome partitioning; KEGG: cth:Cthe_2377 chromosome segregation ATPase; SPTR: Chromosome segregation ATPase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.610 |
| Toce_2276 | ribBA | Toce_2276 | Toce_1693 | COGs: COG1192 ATPase involved in chromosome partitioning; KEGG: cth:Cthe_2377 chromosome segregation ATPase; SPTR: Chromosome segregation ATPase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.642 |
| Toce_2276 | rsmG | Toce_2276 | Toce_2278 | COGs: COG1192 ATPase involved in chromosome partitioning; KEGG: cth:Cthe_2377 chromosome segregation ATPase; SPTR: Chromosome segregation ATPase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain. | Methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. | 0.889 |
| Toce_2276 | topA | Toce_2276 | Toce_1085 | COGs: COG1192 ATPase involved in chromosome partitioning; KEGG: cth:Cthe_2377 chromosome segregation ATPase; SPTR: Chromosome segregation ATPase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.762 |
| Toce_2277 | Toce_2275 | Toce_2277 | Toce_2275 | ParB family protein; COGs: COG1475 transcriptional regulator protein; InterPro IPR003115:IPR004437; KEGG: tte:TTE2792 transcriptional regulator; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: Predicted Transcriptional regulator; TIGRFAM: parB-like partition protein; PFAM: ParB-like nuclease domain; KorB domain; TIGRFAM: ParB-like partition proteins; Belongs to the ParB family. | Chromosome segregation DNA-binding protein; COGs: COG1475 transcriptional regulator protein; InterPro IPR003115:IPR004437; KEGG: tpd:Teth39_2284 ParB-like partition protein; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: ParB-like partition protein; TIGRFAM: parB-like partition protein; PFAM: Helix-turn-helix; ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins; Belongs to the ParB family. | 0.896 |
| Toce_2277 | Toce_2276 | Toce_2277 | Toce_2276 | ParB family protein; COGs: COG1475 transcriptional regulator protein; InterPro IPR003115:IPR004437; KEGG: tte:TTE2792 transcriptional regulator; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: Predicted Transcriptional regulator; TIGRFAM: parB-like partition protein; PFAM: ParB-like nuclease domain; KorB domain; TIGRFAM: ParB-like partition proteins; Belongs to the ParB family. | COGs: COG1192 ATPase involved in chromosome partitioning; KEGG: cth:Cthe_2377 chromosome segregation ATPase; SPTR: Chromosome segregation ATPase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain. | 0.993 |
| Toce_2277 | Toce_2282 | Toce_2277 | Toce_2282 | ParB family protein; COGs: COG1475 transcriptional regulator protein; InterPro IPR003115:IPR004437; KEGG: tte:TTE2792 transcriptional regulator; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: Predicted Transcriptional regulator; TIGRFAM: parB-like partition protein; PFAM: ParB-like nuclease domain; KorB domain; TIGRFAM: ParB-like partition proteins; Belongs to the ParB family. | Membrane protein insertase, YidC/Oxa1 family; COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR001708:IPR020001; KEGG: tpd:Teth39_2292 60 kDa inner membrane insertion protein; PFAM: 60 kDa inner membrane insertion protein; SPTR: 60 kDa inner membrane insertion protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family; PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain. | 0.764 |
| Toce_2277 | dnaA | Toce_2277 | Toce_0001 | ParB family protein; COGs: COG1475 transcriptional regulator protein; InterPro IPR003115:IPR004437; KEGG: tte:TTE2792 transcriptional regulator; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: Predicted Transcriptional regulator; TIGRFAM: parB-like partition protein; PFAM: ParB-like nuclease domain; KorB domain; TIGRFAM: ParB-like partition proteins; Belongs to the ParB family. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.539 |