STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Toce_2281Single-stranded nucleic acid binding R3H domain protein; COGs: COG1847 RNA-binding protein; InterPro IPR001374:IPR004087; KEGG: pth:PTH_2918 RNA binding protein; PFAM: single-stranded nucleic acid binding R3H domain protein; SMART: single-stranded nucleic acid binding R3H domain protein; KH domain protein; SPTR: Predicted RNA binding protein; PFAM: R3H domain. (210 aa)    
Predicted Functional Partners:
Toce_1067
COGs: COG1837 RNA-binding protein (contains KH domain); InterPro IPR004088:IPR020627; KEGG: nth:Nther_1370 RNA-binding protein (KH domain); SPTR: RNA-binding protein (KH domain); PFAM: KH domain; Belongs to the UPF0109 family.
  
 
 0.975
Toce_2282
Membrane protein insertase, YidC/Oxa1 family; COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR001708:IPR020001; KEGG: tpd:Teth39_2292 60 kDa inner membrane insertion protein; PFAM: 60 kDa inner membrane insertion protein; SPTR: 60 kDa inner membrane insertion protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family; PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain.
  
  
 0.965
rsmG
Methyltransferase GidB; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.
  
  
 0.935
rnpA
Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
 
  
 0.925
Toce_2283
Protein of unknown function DUF37; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
  
    0.906
mnmE
tRNA modification GTPase trmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
     
 0.808
Toce_0752
COGs: COG1530 Ribonuclease G and E; InterProIPR003029:IPR002792:IPR004659:IPR018247:IPR 000463:IPR019307; KEGG: sth:STH426 ribonuclease G; PFAM: RNA-binding protein AU-1/Ribonuclease E/G; RNA binding S1 domain protein; deoxyribonuclease/rho motif-related TRAM; SPTR: Ribonuclease G; TIGRFAM: ribonuclease, Rne/Rng family; PFAM: Ribonuclease E/G family; TRAM domain; S1 RNA binding domain; TIGRFAM: ribonuclease, Rne/Rng family.
   
 
 0.796
mnmG
Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family.
     
 0.760
rpmH
LSU ribosomal protein L34P; InterPro IPR000271; KEGG: tte:TTE2802 50S ribosomal protein L34; PFAM: ribosomal protein L34; SPTR: 50S ribosomal protein L34; TIGRFAM: ribosomal protein L34; manually curated; PFAM: Ribosomal protein L34; TIGRFAM: ribosomal protein L34, bacterial type; Belongs to the bacterial ribosomal protein bL34 family.
     
 0.716
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
   
  
 0.670
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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