STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEG78801.1KEGG: amt:Amet_0948 hypothetical protein. (184 aa)    
Predicted Functional Partners:
mprF
Conserved hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
 
    0.953
EEG78800.1
TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein HSR1-related; nucleoside recognition domain protein; KEGG: amt:Amet_0947 small GTP-binding protein.
 
     0.924
EEG77520.1
PFAM: iron-containing alcohol dehydrogenase; KEGG: vei:Veis_2143 iron-containing alcohol dehydrogenase.
  
 0.913
EEG76645.1
PFAM: iron-containing alcohol dehydrogenase; KEGG: pth:PTH_0606 alcohol dehydrogenase.
  
 0.913
EEG77522.1
PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: ter:Tery_2707 glycosyl transferase, family 2.
  
 0.842
EEG76163.1
PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: chy:CHY_1609 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase/isomerase family protein.
  
 
 0.766
EEG78799.1
PFAM: FeoA family protein; KEGG: amt:Amet_0946 FeoA family protein.
       0.749
EEG77107.1
PFAM: VanZ family protein; KEGG: amt:Amet_0776 VanZ family protein.
  
     0.696
EEG77034.1
PFAM: extracellular solute-binding protein family 1; KEGG: amt:Amet_4629 extracellular solute-binding protein, family 1.
  
     0.680
EEG76279.1
PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: bld:BLi01923 L-threonine 3-dehydrogenase.
  
 0.664
Your Current Organism:
Dethiobacter alkaliphilus
NCBI taxonomy Id: 555088
Other names: D. alkaliphilus AHT 1, Dethiobacter alkaliphilus AHT 1, Dethiobacter alkaliphilus DSM 19026, Dethiobacter alkaliphilus str. AHT 1, Dethiobacter alkaliphilus strain AHT 1
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